Results 51 to 60 of about 665,097 (197)

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Effectiveness of Cetrorelix for the Prevention of Premature Luteinizing Hormone Surge during Controlled Ovarian Stimulation Using Letrozole and Gonadotropins: A Randomized Trial

, 2009
OBJECTIVE: To evaluate the effectiveness of a GnRH antagonist in preventing premature LH surge under a letrozole and gonadotropin protocol. DESIGN: Prospective, randomized clinical trial. SETTING: A teaching hospital and tertiary medical center.
LEE, TSUNG-HSIEN;LIN, YU-HUNG;SEOW, KOK -MIN;HWANG, JIANN-LOUNG;TZENG, CHII-RUEY;YANG, YU-SHIH, 李宗賢;林禹宏;蕭國明;黃建榮;曾啟瑞;楊友仕   +1 more
core   +1 more source

Decrease in preovulatory serum estradiol is a valuable marker for predicting premature ovulation in natural/unstimulated in vitro fertilization cycle

Journal of Ovarian Research, 2018
Background Premature ovulation occurs at a high rate in natural-cycle in vitro fertilization (IVF), and cycle cancellation further hampers the overall efficiency of the procedure.
Xuefeng Lu, Shuzin Khor, Qianqian Zhu, Lihua Sun, Yun Wang, Qiuju Chen, Ling Wu, Yonglun Fu, Hui Tian, Qifeng Lyu, Renfei Cai, Yanping Kuang   +11 more
doaj   +1 more source

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

Advanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang, Yuan Liu, Huan Peng, Yu Ni, Zhengqiao Jiang, Chenxuan Yu, Xincheng Zhang, Huayu Kang, Yanchao Liu, Juan Chen, Kai Zhao, Lin Han, Xin Zou, Kai Shu, Xiaochuan Wang, Jian‐Zhi Wang, Ting Lei, Chao Gan, Jianfeng Liu, Huaqiu Zhang   +19 more
wiley   +1 more source

Successful outcome of a pregnancy derived from premature ovulation in a gonadotropin‐releasing hormone antagonist protocol: A case report

Clinical Case Reports, 2021
In the gonadotropin‐releasing hormone (GnRH) antagonist protocol, it is necessary to reinforce contraceptive guidance assuming that luteinizing hormone surge is not detected by measurement of serum level and ovulation is not suppressed by GnRH antagonist.
Daichi Inoue, Yoshimasa Asada, Tomoko Ando   +2 more
doaj   +1 more source

Decoupling Quasi‐Solid‐State Sulfur Conversion Mechanisms in Weakly Solvating and Locally High Concentration Electrolytes

Advanced Energy Materials, EarlyView.
Weakly solvating CME–TTE and localized high‐concentration G2–TTE electrolytes redirect lithium–sulfur chemistry toward quasi‐solid‐state conversion through distinct coordination environments. Molecular dynamics and multimodal electrochemical and spectroscopic measurements show that G2–TTE couples multidentate solvent coordination, anion participation ...
Boyi Pang, Huanxin Li, Liam Bird, Yiming Guo, Bochen Li, Xiaoxia Guo, Roby Soni, Yi Zeng, Paul R. Shearing, Thomas S. Miller, Rhodri Jervis, Alexander J. Kibler, James B. Robinson   +12 more
wiley   +1 more source

Follicular Hormonal Changes and Oocyte Quality in Heifers That Exhibited an LH Surge, no LH Surge, or in Which the LH Surge Was Suppressed With Progestin [PDF]

, 1993
The mechanisms that control follicular development, oocyte maturation and ovulation, are complex and poorly understood in farm animals. Superovulation via gonadotrophin stimulation of the ovaries provides a model to study follicular development and ...
Ferrell, Calvin L., Jenkins, Thomas G.
core  

Evaluation of LH secretory dynamics during the rat proestrous LH surge

, 1999
The preovulatory luteinizing hormone (LH) surge results from the integration of complex interactions among gonadal steroids and hypothalamic and pituitary hormones. To evaluate changes in LH secretory dynamics that occur during the rat LH surge, we have
Lisa A. Kolp, Frank J. Strobl, Johannes D. Veldhuis, Kathleen M. Hoeger   +3 more
core   +1 more source

Personalized multimodal physiological modeling of menstrual cycle dynamics using endocrine, metabolic and wearable signals

Journal of Intelligent Medicine, EarlyView.
Abstract Menstrual cycle tracking remains challenged by the limited physiological scope and inconsistent generalizability of existing wearable‐based approaches, which often rely on individual sensing modalities that incompletely capture the complexity of menstrual physiology.
Ejay Nsugbe, Georgianna Lin
wiley   +1 more source

Efficacy of Progestin Primed Ovarian Stimulation versus GnRH Antagonist Protocols in Clomiphene Resistant PCOS Undergoing ICSI Cycles. Randomized Controlled Trial (RCT) aa [PDF]

Minia Journal of Medical Research
Background: Polycystic ovary syndrome (PCOS) is one of the endocrine disorders and anovulatory cycles of reproductive age women, it represents 70% of anovulation.
Mohamed Abdel Hameed, Ayman Abdel Megeed, Reham Taha, Manar Elsayed Amin   +3 more
doaj   +1 more source