Dydrogesterone and Letrozole Combination for the Treatment of Endometriosis: A Mechanism-Based Therapeutic Approach [PDF]
Endometriosis is a complex, estrogen-dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology.
Santosh Kumar Rai +3 more
doaj +2 more sources
Effectiveness of oral dydrogesterone compared to placebo in reducing the risk of preterm birth: a systematic review and meta-analysis [PDF]
Background Preterm birth remains a major contributor to neonatal morbidity and mortality worldwide. Oral dydrogesterone is used in some clinical settings for preterm birth prevention, despite uncertainty regarding its effectiveness.
Sohieb Hedawy +6 more
doaj +2 more sources
Effect of hysteroscopic cold‑knife resection combined with dydrogesterone therapy on natural conception outcomes in women with endometrial polyps [PDF]
Introduction: This study was conducted to explore the impact of hysteroscopic cold-knife resection (HCKR) combined with dydrogesterone on natural conception in patients with endometrial polyps (EPs).
Bingxue Xu, Shan Xu, Weiwei Guo
doaj +2 more sources
Efficacy and safety of dydrogesterone monotherapy versus estradiol–dydrogesterone combination therapy in perimenopausal women: a real-world cohort study [PDF]
ObjectiveTo compare the 12-week effectiveness and safety of dydrogesterone monotherapy versus estradiol–dydrogesterone (E2/DYD) combination therapy in women with perimenopausal symptoms in a real-world clinical setting.MethodsThis retrospective cohort ...
Shuaiting Liu, Yuhui Zeng, Zhen Huang
doaj +2 more sources
Efficacy and safety of estradiol/dydrogesterone combined with escitalopram in the treatment of anxiety and depression in perimenopausal women: a randomized controlled trial [PDF]
BackgroundTo investigate the efficacy and underlying mechanisms of a combined therapy of estradiol/dydrogesterone and escitalopram in treating perimenopausal anxiety and depression.MethodsA total of 195 patients were randomized to receive escitalopram ...
Shufang Wu +36 more
doaj +2 more sources
Age-stratified analysis of euploidy rates in Progestin-Primed Ovarian Stimulation (PPOS) utilizing micronized progesterone or dydrogesterone versus GnRH analogues [PDF]
Purposes This study aims to analyze the euploidy rates of PPOS utilizing micronized progesterone and dydrogesterone in comparison to conventional controlled ovarian stimulation (COS) protocols in pre-implantation genetic testing for aneuploidy (PGT-A ...
Rang Liu +8 more
doaj +2 more sources
Gu Ben An Tai decoction combined with dydrogesterone for early threatened abortion secondary to spleen and kidney deficiency: a retrospective observational study [PDF]
Background In this retrospective observational study, we aimed to evaluate the clinical efficacy and safety of Gu Ben An Tai Decoction (GBATD) combined with dydrogesterone for treating threatened abortion (TA).
Xuebing Li +5 more
doaj +2 more sources
Background: Despite some progress has been made in the pathogenesis and treatment of threatened miscarriage (TM), conventional treatment remains suboptimal.
Kai Chen +5 more
doaj +1 more source
ObjectiveThe need of luteal support after FET is no longer to be proven. Different routes of progesterone administration are available with interindividual differences in metabolization and serum progesterone levels, the latter being highly correlated ...
Virginie Simon +11 more
doaj +1 more source
Background Allylestrenol is an oral progestogen being increasingly used for luteal phase support in assisted reproductive techniques. However, evidence of the clinical efficacy of allylestrenol in luteal phase support is lacking.
Yuexin Yu +7 more
doaj +1 more source

