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Mechanisms of Premature Menopause
Endocrinology and Metabolism Clinics of North America, 2005Premature menopause is characterized by amenorrhea, elevated circulating gonadotropin levels, and low circulating estrogen levels in women under the age of 40 years. Although hormonal values are similar to those found during the menopausal transition and after menopause, it is clear that women with this disorder differ in important ways from normal ...
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1976
It is not possible to provide a completely satisfactory definition of the premature menopause. Ideally the definition should be based on accurate epidemiological studies so that its timing could be stated, in years, as two standard deviations less than the (appropriate) population’s mean age at the final cessation of menstruation.
H. S. Jacobs, M. A. F. Murray
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It is not possible to provide a completely satisfactory definition of the premature menopause. Ideally the definition should be based on accurate epidemiological studies so that its timing could be stated, in years, as two standard deviations less than the (appropriate) population’s mean age at the final cessation of menstruation.
H. S. Jacobs, M. A. F. Murray
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Premature menopause increases cardiovascular risk
Climacteric, 2009Premature menopause and bilateral oophorectomy in young women are associated with an increased incidence of cardiovascular disease, myocardial infarction and overall mortality. Observational studies suggest an interval of 5-10 years between loss of ovarian function and the increased risk of cardiovascular disease.
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Bilateral oophorectomy and premature menopause
The American Journal of Medicine, 2005The ovary is a complex metabolic organ. The follicles produce both androgens and estrogens, whereas the stromal tissue synthesizes androgens only. When menopause occurs, both androgen and estrogen levels decrease. The postmenopausal ovary remains a source of endogenous androgens that are converted to estrogen.
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Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1993
This article describes the different etiologies and clinical aspects of precocious menopause as well as the investigations necessary to differentiate between a syndrome of resistant ovaries and pituitary tumors. Therapeutic aspects such as estrogen substitution and oocyte donation are discussed.
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This article describes the different etiologies and clinical aspects of precocious menopause as well as the investigations necessary to differentiate between a syndrome of resistant ovaries and pituitary tumors. Therapeutic aspects such as estrogen substitution and oocyte donation are discussed.
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Premature ovarian insufficiency, early menopause, and induced menopause
Best Practice & Research Clinical Endocrinology & MetabolismPremature ovarian insufficiency (POI) is a condition in which there is a decline in ovarian function in women who are younger than 40 years resulting in a hypo-oestrogenic state with elevated gonadotrophins and oligomenorrhoea/amenorrhoea. This leads to short term complications of menopausal symptoms and long-term effects on bone and cardiovascular ...
Haitham, Hamoda, Angela, Sharma
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BMJ, 2008
Grant’s blanket statement,1 based on the WISDOM study,2 that “it would be irresponsible to think that any …
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Grant’s blanket statement,1 based on the WISDOM study,2 that “it would be irresponsible to think that any …
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Premature menopause management.
Australian family physician, 1992Premature menopause is most commonly iatrogenic, but may be due to an autoimmune or other ovarian disorder, or it may be idiopathic. The diagnosis is established by a raised serum FSH. Fertility can only be reliably achieved using donor oocytes; otherwise oestrogen replacement therapy should be offered.
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