Results 41 to 50 of about 2,087,459 (277)

Changes in expression of TNF alpha and its receptors mRNAs in oocytes and granulosa cells in mice with experimental immune ovarian failure [PDF]

open access: yes, 2014
Purpose: To investigate the expression of TNF- α and its receptors (types I and II) at mRNA level in oocytes and granulose cells as well as to study effect of TNF-α on follicular cell death in mice with experimental immune ovarian failure induced by ...
Grushka, Nataliya   +4 more
core   +1 more source

Premature ovarian failure in twins: case report [PDF]

open access: yes, 2016
Premature ovarian failure (POF)is a serious life-changing condition that affects young women, remains an enigma and the researchers’ challenge.
Wanyoike-Gichuhi, J.   +3 more
core   +1 more source

Inhibin and premature ovarian failure [PDF]

open access: yesHuman Reproduction Update, 2009
Elucidation of the causes of premature ovarian failure (POF) is difficult due to the heterogeneity of the condition. Inhibin is a potential candidate gene for POF based on its dual actions on FSH secretion by the pituitary and gametogenesis in the gonads.
A L, Chand, C A, Harrison, A N, Shelling
openaire   +2 more sources

Premature menopause and autoimmune primary ovarian insufficiency in two international multi-center cohorts

open access: yesEndocrine Connections, 2022
Objective: To investigate markers of premature menopause (
Elinor Chelsom Vogt   +23 more
doaj   +1 more source

Primary ovarian leiomyoma in young woman with premature ovarian failure [PDF]

open access: yes, 2018
Authors present a rare case of primary ovarian leiomyoma in a young female with premature ovarian failure. A 39-year-old female with premature ovarian failure presented with large unilateral adnexal mass, with mildly elevated CA-125 levels, underwent ...
Nangia, Anita   +2 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro   +6 more
wiley   +1 more source

Premature ovarian failure

open access: yes, 1977
Twelve cases of premature ovarian failure (POF) are described. The clinical, hormonal, histopathologic and cytogenetic studies of each patient have been presented.
Peter, J.   +7 more
core   +2 more sources

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

open access: yesArthritis Care &Research, EarlyView.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci   +25 more
wiley   +1 more source

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

open access: yesAngewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen   +3 more
wiley   +2 more sources

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