Early menopause: A hazard to a woman's health [PDF]
Early menopause or premature ovarian insufficiency (POI) is a common cause of infertility in women and affects about one per cent of young women. This disorder has significant psychological sequelae and major health implications.
Castelo-Branco Flores, Camil +1 more
core +1 more source
Risk factors for ovarian failure in patients with systemic lupus erythematosus
The aim of the present study was to identify the risk factors for ovarian failure in patients with systemic lupus erythematosus. Seventy-one women aged 17 to 45 years with systemic lupus erythematosus were studied.
M.M.C. Medeiros +3 more
doaj +1 more source
Clinical and laboratory criteria for occult form of premature ovarian failure [PDF]
Purpose of the study. To develop clinical and laboratory criteria characteristic of the occult (hidden) form of premature ovarian failure. Material and methods.
L A Marchenko, R I Mashaeva
doaj +1 more source
Ovarian Reserve in Women Treated for Acute Lymphocytic Leukemia or Acute Myeloid Leukemia with Chemotherapy, but Not Stem Cell Transplantation [PDF]
Purpose: It is well known that chemotherapy regimens may have a negative effect on ovarian reserve, leading to amenorrhea or premature ovarian failure. There are little data regarding the effects of leukemia chemotherapy on ovarian reserve, specifically ...
Correia, Katharine Fischer Berry +4 more
core +3 more sources
Factors influencing premature ovarian insufficiency: a systematic review and meta-analysis
Background Premature ovarian insufficiency (POI) has multiple contributing factors. This study aims to systematically evaluate these factors and their mechanisms, identify high-risk groups, support early intervention, and provide a basis for future ...
Shuling Lin, Shanyan Chen, Qin Zhang
doaj +1 more source
MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex. [PDF]
MCM8-9 complex is required for homologous recombination (HR)-mediated repair of double-strand breaks (DSBs). Here we report that MCM8-9 is required for DNA resection by MRN (MRE11-RAD50-NBS1) at DSBs to generate ssDNA.
Dutta, Anindya +6 more
core +1 more source
A Consanguinity Related Autosomal Translocation which Leads to Premature Ovarian Failure [PDF]
The premature ovarian failures with underlying chromosomal abnormalities are normally X-linked, although their associations with the autosomal and the Robertsonian translocations are also possible.
Mot Yee Yik +3 more
doaj +1 more source
Ovarian aging and premature ovarian failure
Physiological reproductive aging occurs as a result of a decrease in the number and quality of oocytes in ovarian cortex follicles. Although the reason for the decrease in the quality of the pool and follicular oocytes is not fully understood, endocrine, paracrine, genetic, and metabolic factors are thought to be effective.
Yavuz Emre, Sükür +2 more
openaire +2 more sources
Pathogenesis and Causes of Premature Ovarian Failure: An Update [PDF]
Premature ovarian failure (POF) affects 1% of young women. This condition has significant psychological sequelae and major health implications. POF seriously interferes with fertility and family planning. Diverse etiologies are associated with POF.
Mahbod Ebrahimi, Firoozeh Akbari Asbagh
doaj
Qin et al. report that an agonistic antibody targeting the BDNF receptor TrkB promotes follicle development and oocyte maturation, and reverse ovarian deficits and infertility in aged and cyclophosphamide-induced premature ovarian failure model mice.
Xunsi Qin +6 more
doaj +1 more source

