Results 51 to 60 of about 2,087,459 (277)

Ovarian aging and premature ovarian failure

Journal of the Turkish German Gynecological Association, 2014
Physiological reproductive aging occurs as a result of a decrease in the number and quality of oocytes in ovarian cortex follicles. Although the reason for the decrease in the quality of the pool and follicular oocytes is not fully understood, endocrine, paracrine, genetic, and metabolic factors are thought to be effective.
Yavuz Emre, Sükür, Içten Balık, Kıvançlı, Batuhan, Ozmen   +2 more
openaire   +2 more sources

GYNAECOGRAPHY IN PREMATURE OVARIAN FAILURE AND OVARIAN DYSGENESIS [PDF]

Obstetrical & Gynecological Survey, 1969
Gynaecography—the radiological visualization of the internal female genitalia after pneumoperitoneum—is a safe and simple procedure. When taken in conjunction with the clinical and laboratory findings the results of gynaecography are often a sufficient basis for diagnosis and a plan of management in women presenting with menstrual irregularity or ...
L, Kreel, J, Ginsburg, M F, Green
openaire   +2 more sources

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Premature ovarian failure: problems and prospects (literature review)

Клинический разбор в общей медицине
Relevance. Premature ovarian failure is a condition characterized by loss of ovarian function in women under 40 years of age, occurring against the background of dysfunction or depletion of ovarian follicles, which leads to oligo/amenorrhea ...
Tatyana Yu. Pestrikova, Tatyana I. Yurasova   +1 more
doaj   +1 more source

CSB-PGBD3 Mutations Cause Premature Ovarian Failure. [PDF]

PLoS Genetics, 2015
Premature ovarian failure (POF) is a rare, heterogeneous disorder characterized by cessation of menstruation occurring before the age of 40 years. Genetic etiology is responsible for perhaps 25% of cases, but most cases are sporadic and unexplained.
Yingying Qin, Ting Guo, Guangyu Li, Tie-Shan Tang, Shidou Zhao, Xue Jiao, Juanjuan Gong, Fei Gao, Caixia Guo, Joe Leigh Simpson, Zi-Jiang Chen   +10 more
doaj   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Risk factors for ovarian failure in patients with systemic lupus erythematosus

Brazilian Journal of Medical and Biological Research, 2001
The aim of the present study was to identify the risk factors for ovarian failure in patients with systemic lupus erythematosus. Seventy-one women aged 17 to 45 years with systemic lupus erythematosus were studied.
M.M.C. Medeiros, V.A.L. Silveira, A.P.T. Menezes, R.C. Carvalho   +3 more
doaj   +1 more source

Paternal Sperm Gnas‐ICR Epigenetic Programming Contributes to PPP‐Like Phenotypes in Female Offspring

Advanced Science, EarlyView.
A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang, Lu Chen, Tiancheng Wu, Yating Li, Hui Wang   +4 more
wiley   +1 more source

Factors influencing premature ovarian insufficiency: a systematic review and meta-analysis

Journal of Obstetrics and Gynaecology
Background Premature ovarian insufficiency (POI) has multiple contributing factors. This study aims to systematically evaluate these factors and their mechanisms, identify high-risk groups, support early intervention, and provide a basis for future ...
Shuling Lin, Shanyan Chen, Qin Zhang
doaj   +1 more source

Interference of ATP‐Binding Cassette Transporter by Functional Nano‐Delivery System for High Efficiency Management of Insecticide‐Resistant Nilaparvata lugens

Advanced Science, EarlyView.
A ZIF‐90 nanocarrier delivers dinotefuran and suppresses NlABCG3 and NlABCH1 in resistant Nilaparvata lugens. This system combines pH/ATP‐triggered release with enhanced foliar retention, improving efficacy while sparing honeybees and promoting rice growth, offering a promising resistance‐breaking strategy.
Chengshuai He, Hejun Ren, Shuo Zhang, Jikang Cheng, Hui Zhang, Jiao Liu, Sijie Wang, Congfen Gao, Yanchao Zhang, Yunhao Gao   +9 more
wiley   +1 more source