Results 71 to 80 of about 3,287 (210)

Successful pregnancy with tripterygium glycoside-induced premature ovarian insufficiency: a case report

open access: yesJournal of International Medical Research, 2019
Premature ovarian insufficiency is characterized by reduced ovarian function in a young woman, resulting in an earlier menopause compared with women with normal ovarian function.
Yuan Yang, Xiao-Ling Ma, Xue-Hong Zhang
doaj   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

open access: yesAdvanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova   +4 more
wiley   +1 more source

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12‐Related Developmental Disorders

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken   +4 more
wiley   +1 more source

Optimization and verification of high‐fat diet formulation for establishing a rat model of obesity‐related precocious puberty

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We identified 45% HFD as the optimal formulation to establish a juvenile rat model of obesity‐related precocious puberty. It elicits robust phenotypic (early vaginal opening, obesity), histological (advanced ovarian development), and endocrine (elevated HPG axis hormones) alterations, with leptin‐mediated GnRH secretion as a core mechanistic driver ...
Jiayi Gong   +5 more
wiley   +1 more source

Novel treatment approach to the premature ovarian failure in women of reproductive age with pelvic inflammatory disease [PDF]

open access: yesРМЖ. Мать и дитя, 2019
Novel treatment approach to the premature ovarian failure in women of reproductive age with pelvic inflammatory disease N.A. Burova1, T.A. Selezneva2, O.V.
N.A. Burova   +2 more
doaj  

Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe   +3 more
wiley   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell   +3 more
wiley   +1 more source

Classical music restored fertility status in rat model of premature ovarian failure [PDF]

open access: green, 2022
Nahideh Nazdikbin   +8 more
openalex   +1 more source

A Case of Pregnancy Following Treatment of Ovarian Failure with Persian Medicine: A Case Report

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2021
BACKGROUND AND OBJECTIVE: Premature ovarian failure, with a prevalence of 1% in women under the age of 40, leads to serious health problems for women of childbearing age.
M Mohajeranirad, SA Latifi, M Salehi
doaj  

PREMATURE OVARIAN FAILURE (POF)

open access: yesMaturitas, 2009
Last 5-10 years, more and more scientists globally consider use of Hormonal Replacement Therapy HRT in women with POF, despite the cause of this event. Objectives: To develop proper management for POF patients. Methods: Statistical, sociological, medical.
openaire   +2 more sources

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