Results 81 to 90 of about 763 (215)

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Fetuses exposed to an episode of threatened preterm labor delivered at or near term show signs of cardiac remodeling

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To evaluate whether fetuses exposed to threatened preterm labor (PTL) without intra‐amniotic infection or inflammation (IAI), who were born ≥ 34 weeks' gestation, show signs of cardiac remodeling and dysfunction at admission and 4 weeks after the episode of threatened PTL.
C. Murillo, M. Palacio, C. Rueda, M. Larroya, D. Boada, J. Ponce, M. Guilleumes, O. Gómez, S. Ferrero, E. Gratacós, F. Crispi, T. Cobo   +11 more
wiley   +1 more source

Does the use of probiotics in pregnant women with premature rupture of membranes improve the maternal and perinatal outcome?

DST, 2018
Introduction: Premature rupture of membranes (PROM) is a condition that affects 8–10% of all pregnancies, and contributes with 20–40% of preterm deliveries.
Denise Vasconcelos de Moraes, José Eleutério Junior, Camylla Santos de Souza   +2 more
doaj  

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Reproductive Challenges of the Ageing Female: A Comprehensive Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Changes in societal norms over the last few decades have resulted in novel family planning trends, notably delayed childbearing and increased maternal age at the birth of the first child. Despite advances in reproductive medicine, ageing poses significant challenges.
Sofia Bitzika, Meletios P. Nigdelis, Angelos Daniilidis, Erich‐Franz Solomayer, Irene Lambrinoudaki, Efstratios M. Kolibianakis, Dimitrios G. Goulis   +6 more
wiley   +1 more source

[Premature rupture of fetal membranes and chorioamnionitis].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1994
The article presents a survey of preterm rupture of the amniotic membranes at term (more than 1 hour prior to uterine contractions) and preterm (< 37 weeks). The diagnosis of rupture can be suspected from the history alone in 90% of the cases, and confirmed by inspection.
K, Haram, H O, Daugaard
openaire   +1 more source

High Versus Low Transvaginal Cerclage and Pregnancy Outcomes: A Secondary Analysis of the C‐STICH Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To compare pregnancy outcomes following high versus low vaginal cerclage in women at high risk of preterm birth. Design Secondary analysis of a multi‐centre randomised control trial. Setting Obstetric units across the UK. Sample Women participating in the C‐STICH trial who received a transvaginal cerclage. Methods Cerclage height was
Laura van der Krogt, Nicole Pilarski, Victoria Hodgetts Morton, Alexandra Emms, Philip Toozs‐Hobson, Lee Middleton, Andrew Shennan, Catherine A. Moakes   +7 more
wiley   +1 more source

Maternal and fetal outcome of preterm premature rupture of membranes in less than 37 weeks of gestation in a tertiary care hospital - A prospective observational study

National Journal of Physiology, Pharmacy and Pharmacology
Background: Preterm premature rupture of membrane (PPROM) is the spontaneous rupture of fetal membranes before the onset of labor and before 37 weeks of gestation. This prospective study was done to know the materno-fetal outcome in the same.
Jatoth Madhavi Bai, Vasantha Kumari K P, Jaimie T Jacob, Lakshmi Vinodh S   +3 more
doaj   +1 more source

Genotype‐directed therapy for non–small cell lung cancer diagnosed during pregnancy: A pooled analysis of seven cases from the Cancer and Pregnancy Registry with maternal and neonatal outcomes and review of the literature

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this retrospective case series from a single database of pregnant women with cancer, seven were diagnosed with non‐small cell lung cancer (NSCLC). Chemotherapy and in some cases also biomarker‐directed therapy during pregnancy were associated with disease control allowing delivery closer to term and resulting in improved maternal outcomes compared ...
Reed Firestone, Elyce Cardonick
wiley   +1 more source

Survey of Pregnancy Outcome in Preterm Premature Rupture of Membranes with Amniotic Fluid Index <5 and ≥5

Oman Medical Journal, 2010
Objectives: Preterm premature rupture of membranes (PPROM) is among the most important causes of perinatal morbidity and mortality. The aim of this study is to survey the pregnancy outcomes in preterm premature rupture of membranes with an amniotic fluid
Fatemeh Tavassoli, Marzieh Ghasemi, Ashraf Mohamadzade, Jamileh Sharifian   +3 more
doaj