Results 171 to 180 of about 44,110 (224)

A premature termination codon mutation in the onion <i>AcCER2</i> gene is associated with both glossy leaves and thrip resistance. [PDF]

Hortic Res
Lei P, Pan M, Kang S, Zeng P, Ma Y, Peng Y, Ma X, Chen W, He L, Yang H, Li W, Zhang S, Hui L, Cai J.   +13 more
europepmc   +1 more source

Influence of MC1R Gene Variants on Coat Color of Indicine Cattle Breeds

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Indicine cattle display a broad range of coat colors, representing a relevant and breed‐defining trait required for registration in breeder association. Among the genes involved in pigmentation, MC1R stands out for modulating the synthesis of melanin‐related proteins and remains poorly explored in indicine cattle breeds. Therefore, we aimed to
Silel V. S. A. Maciel, Ingrid P. P. Oliveira, Beatriz B. Senes, Carolaine J. S. Santana, Jackeline S. Alves, Edilane A. da Silva, Fernando O. Franco, Bárbara C. F. da Silva, Fernando C. Cairo, Frederico C. Cairo, Aníbal E. Vercesi‐Filho, Raphael B. Costa, Gregório M. F. de Camargo   +12 more
wiley   +1 more source

CHAMP1 premature termination codon mutations found in individuals with intellectual disability cause a homologous recombination defect through haploinsufficiency. [PDF]

Sci Rep
Yoshizaki Y, Ouchi Y, Kurniawan D, Yumoto E, Yoneyama Y, Rizqullah FR, Sato H, Sarholz MH, Natsume T, Kanemaki MT, Ikeda M, Ui A, Iemura K, Tanaka K.   +13 more
europepmc   +1 more source

From Multiple Congenital Anomalies to Pituitary Gland Malformation: Wide Spectrum of Clinical Features in a Family With FOXA2 Variant

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1452-1457, June 2026.
ABSTRACT FOXA2 (hepatocyte nuclear factor‐3β, HNF‐3β) encodes a transcriptional activator involved in early embryogenesis, particularly in the patterning and differentiation of midline structures such as the neural tube, foregut, and pituitary gland. Its role in human pathogenesis was first suspected when patients with deletion of chromosome 20p11.2 ...
Christopher Connolly, Hemant A. Parmar, Lauren Hipp, Tomoyasu Higashimoto   +3 more
wiley   +1 more source

An antiviral jacalin‐like lectin gene contributes to nonhost resistance and host determination of potexviruses among Brassicaceae

New Phytologist, Volume 250, Issue 5, Page 3283-3298, June 2026.
Summary Plant resistance influences the host range of pathogens; however, the mechanism driving this influence remains poorly understood. Brassicaceae species are not natural hosts of potexviruses, for reasons that have not yet been determined. This study investigated the molecular basis of nonhost resistance (NHR) to potexviruses in the Brassicaceae ...
Takumi Suzuki, Kazuya Ishikawa, Akira Yusa, Nozomu Iwabuchi, Kan Kimura, Tetsuya Yoshida, Mari Ota, Masato Suzuki, Masanobu Nishikawa, Kensaku Maejima, Shigetou Namba, Yasuyuki Yamaji   +11 more
wiley   +1 more source

Comparative Analysis Reveals the Adaptive Evolution of Olfactory System in the Swamp Eel (Monopterus albus) Based on the Chromosome‐Level Genome

Ecology and Evolution, Volume 16, Issue 5, May 2026.
A total of 629 gene families were identified to expand in the swamp eel, with five (OLFR, GNAL, PRKG1, NCALD, and PDE1) distributed in olfactory transduction (KEGG map04740). A total of 318 OR genes (289 functional genes, 10 partial genes, and 19 pseudogenes) were annotated in the swamp eel genome, significantly surpassing other fish species.
Chuang Zhou, Zhongyi Wang, Chenhao Zhang, Zhaobin Song   +3 more
wiley   +1 more source

Adapted Live SARS‐CoV‐2 Vaccine Elicits Rapid Mucosal Immunity, Protects From Disease, and Reduces Shedding of XBB.1.5

European Journal of Immunology, Volume 56, Issue 5, May 2026.
An attenuated live vaccine (OTS‐300) expressing the XBB.1.5 Spike provided rapid and complete protection against homologous challenge in the hamster model, accompanied by fast systemic and mucosal antibody responses and markedly reduced transmission compared with XBB.1.5 mRNA vaccination.
Jana Kochmann, Tobias Britzke, Nico Joël Halwe, Lorenz Ulrich, Angele Breithaupt, G. Tuba Barut, Nadine Ebert, Bettina Salome Trüeb, Volker Thiel, Anca Dorhoi, Martin Beer, Donata Hoffmann, Björn Corleis, Jacob Schön   +13 more
wiley   +1 more source

Aminoacyl‐tRNA Synthetases: Variant Classification, Functional Assays, and Emerging Therapeutic Strategies

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Aminoacyl‐tRNA synthetases (aaRS) are essential enzymes that charge tRNAs with their corresponding amino acids, playing a critical role in protein synthesis. All 37 nuclear‐encoded ARS genes, comprising both cytosolic (ARS1) and mitochondrial (ARS2) isoforms, have now been linked to human disease.
M. I. Mendes, D. E. Smith, V. Spek, A. M. Bosch, W. E. Corpeleijn, M. Engelen, S. A. Fuchs, A. Hadchouel, I. U. Heinemann, R. H. Houtkooper, E. M. M. Hoytema van Konijnenburg, S. Kemp, M. Langeveld, C. D. M. Karnebeek, A. Pop, V. M. Siu, N. I. Wolf, G. S. Salomons   +17 more
wiley   +1 more source

RNA Modifications: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 5, May 2026.
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao, Tingwen Xiang, Chuan Yang, Xiaohua Wang, Gang Huang, Fei Luo, Zhao Xie, Yueqi Chen   +7 more
wiley   +1 more source