Results 181 to 190 of about 418,363 (219)
Ataluren and similar compounds (specific therapies for premature termination codon class I mutations) for cystic fibrosis. [PDF]
Aslam AA +3 more
europepmc +1 more source
Characterization of carABpyrB operon and role of pyrE in Francisella novicida biofilm
Pyrimidine biosynthesis links metabolism to biofilm regulation in Francisella novicida. During nutrient limitation, reduced pyrimidine availability shifts metabolism from uracil salvage to de novo synthesis, increasing biofilm formation. Mutants in carABpyrB exhibit uracil‐dependent growth defects and elevated biofilm:growth ratios, revealing ...
Katie C. Sprinkel +2 more
wiley +1 more source
The mediator subunit SlMED25 and the co‐repressor SlSPX2 competitively bind the N‐terminal domain of the phosphate starvation response transcription factor SlPHR3 in tomato to form a sensitive molecular switch, which dynamically modulates phosphate starvation responses and maintains phosphate homeostasis, offering valuable targets for breeding low ...
Mingtong Zhai +10 more
wiley +1 more source
The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba +14 more
wiley +1 more source
Abstract A recent study showed that female medaka lacking the estrogen receptor gene esr2b are unreceptive to male courtship and instead court other females. In this study, we investigated the brain transcriptome of esr2b‐deficient females to explore the underlying mechanisms of this behavioral phenotype, and identified npyb, one of the two ...
Yuki Homan +9 more
wiley +1 more source
A chloroplast‐associated STAY‐GREEN protein, NtSGRL1, acts as a negative regulator of antiviral immunity in tobacco. Disruption of NtSGRL1 enhances resistance to diverse plant viruses and reveals a previously unrecognized link between chloroplast regulation and immune signalling.
Ming Gu +10 more
wiley +1 more source
The miR167–ARF8 module coordinates stamen–pistil development and fruit set in tomato
SlMIR167a is the functionally prominent SlMIR167 gene in tomato fruit development. Summary Auxin is an important regulator of reproductive development. The families of the AUXIN RESPONSE FACTOR (ARF) genes, important components of the auxin signal, have expanded in flowering plants.
Nave Man +7 more
wiley +1 more source
Durum Wheat cv. Svevo Reference Genome Rel.2.0: A Comprehensive Tool for Wheat Genomics
ABSTRACT Advancements in plant genome sequencing and assembly have enabled the production of increasingly accurate and contiguous genome sequences. Here, we present the chromosome‐level assembly of the durum wheat (Triticum turgidum L. ssp. durum, cv. Svevo) reference genome produced using accurate long‐reads, optical mapping and Hi‐C. The new assembly
Elisabetta Mazzucotelli +71 more
wiley +1 more source
Genomic Confirmation of HLA-A*02:94N By Next-Generation Sequencing. [PDF]
Merschman J +4 more
europepmc +1 more source
The CaM1‐CBP60b‐MYB77 Transcriptional Cascade Regulates K+ Homeostasis and Salt Tolerance in Barley
ABSTRACT Soil salinity is a major abiotic stress that threatens global crop productivity. Calcium (Ca2+) is a pivotal second messenger in plant stress signalling, but how Ca2+ sensors such as calmodulin (CaM) transcriptionally control ion homeostasis and salt tolerance remains largely understood in crops.
Yunfeng Xu +18 more
wiley +1 more source

