Results 41 to 50 of about 1,479 (196)

The role of kisspeptin and MKRN3 in the diagnosis of central precocious puberty in girls

open access: yesEndocrine Connections, 2021
Objective: To evaluate the characteristics and significance of serum kissp eptin and makorin ring finger protein 3 (MKRN3) levels for the diagnosis o f central precocious puberty (CPP) in girls.
Mei Li   +5 more
doaj   +1 more source

Activating GNAS1 gene mutations in patients with premature thelarche [PDF]

open access: yes, 2004
Objective To identify GNAS1 gene mutations in girls with exaggerated and/or chronic fluctuating thelarche for at least 1-year duration with no other signs of precocious puberty, skeletal dysplasia, or typical skin lesions of McCune-Albright syndrome ...
Cassorla Goluboff, Fernando   +5 more
core   +1 more source

Increase of Consultations for Premature Thelarche and the Post-Diagnostic of Precocious and Accelerated Puberty in Pediatric Endocrinology in Alava, due to the Confinement Measures Endured in 2019 due to the COVID-19 Pandemic

open access: yes, 2022
Introduction: Due to the COVID 19 pandemic and home confinement measures, many of our routine and daily habits have been both affected and modified.
Leyre Aurora Vilella San Martin
core   +1 more source

Vascular health and exercise in females throughout the lifespan: Exploring puberty, pregnancy and menopause

open access: yesExperimental Physiology, Volume 111, Issue 6, Page 2840-2859, 1 June 2026.
Abstract This narrative review highlights the impact of exercise on vascular health in females over the lifespan with an emphasis on puberty, pregnancy and menopause. These events encompass substantial changes in sex hormone levels, particularly oestrogens and progesterone.
Kathleen B. Miller   +2 more
wiley   +1 more source

Clinical data and basal gonadotropins in the diagnosis of central precocious puberty in girls

open access: yesEndocrine Connections, 2021
Objective: The objective of this study was to analyze whether some auxological characteristics or a single basal gonadotropin measurement will be sufficient to distinguish the prepubertal from pubertal status.
Teodoro Durá-Travé   +5 more
doaj   +1 more source

Review of the Literature on Current Changes in the Timing of Pubertal Development and the Incomplete Forms of Early Puberty

open access: yesFrontiers in Pediatrics, 2019
Puberty is a sensitive period of life characterized by the appearance of secondary sex characteristics which leads to a complete sexual maturation. It physiologically starts between the age of 8 and 13 years in girls and 9 and 14 years in boys.
Giovanni Farello   +4 more
doaj   +1 more source

Assessing Pubertal Timing, Duration, and Related Characteristics in ASXL‐Related Disorders: A Cross‐Sectional Caregiver Survey Analysis

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 1, Page 35-58, January 2026.
ABSTRACT Limited studies have been conducted on pubertal development in populations with pre‐existing medical conditions. More than 20‐fold increased risk of early puberty has been reported in neurodevelopmental disorders; however, this is a heterogeneous group.
Amanda Piring   +4 more
wiley   +1 more source

Medicinal Plants for Acne Vulgaris: An Evidence‐Based Review of Treatments Promoted by Social Media

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 1, January 2026.
ABSTRACT Background Acne vulgaris refers to a chronic inflammatory state of the pilosebaceous follicles that affects the majority of adolescents. Treatments encompass topical agents and systemic therapies. Nowadays, we encounter a growing tendency to use herbal remedies, which raises concerns about misinformation disseminated by digital platforms.
Mohammad Mahdi Parvizi   +6 more
wiley   +1 more source

Premature Thelarche Cases Attending Well-Child Care Surveillance Unit

open access: yes, 2011
Objective: Early sexual maturation has been attributed to some environmental factors in recent years. Therefore, we aimed to evaluate the cases with premature thelarche.
Darendeliler, Fatma Feyza   +3 more
core   +1 more source

Novel Nonsense Mutation in SMARCD2 Gene Results in Dysplasia of All Myeloid Cell Lines

open access: yeseJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Introduction Specific granule deficiency type II (SGD2) is a rare heterogeneous congenital disease characterized by early‐onset life‐threatening infections. SGD2 is caused by autosomal recessive mutations in the SMARCD2 gene. Methods Prenatal screening in our patient revealed a novel homozygous nonsense mutation in SMARCD2 (c.208C>T, p.Gln70*).
Michelle A. E. Brouwer   +6 more
wiley   +1 more source

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