Results 61 to 70 of about 1,479 (196)

Outcomes of Patients With Familial Central Precocious Puberty due to Mutations of MKRN3 Gene After Treatment With Gonadotropin‐Releasing Hormone Agonist

International Journal of Endocrinology, Volume 2025, Issue 1, 2025.
Objective To assess the therapeutic effects of gonadotropin‐releasing hormone agonist (GnRHa) on children with familial central precocious puberty (FCPP) due to Makorin ring finger Protein 3 (MKRN3) gene mutations. Methods Children with central precocious puberty (CPP) who were admitted to the Pediatric Endocrinology Department of Shanghai Ruijin ...
Ziwei Chen, Wenying Li, Junqi Wang, Zhiya Dong, Chuanyin Li, Wei Wang, Ronggui Hu, Xiaoyu Ma, Yuan Xiao, Wenli Lu, Suraiya Saleem   +10 more
wiley   +1 more source

Society for endocrinology guideline for understanding, diagnosing and treating female hypogonadism

Clinical Endocrinology, Volume 101, Issue 5, Page 409-442, November 2024.
Abstract Female hypogonadism (FH) is a relatively common endocrine disorder in women of premenopausal age, but there are significant uncertainties and wide variation in its management. Most current guidelines are monospecialty and only address premature ovarian insufficiency (POI); some allude to management in very brief and general terms, and most ...
Channa N. Jayasena, Kerri Devine, Katie Barber, Alexander N. Comninos, Gerard S. Conway, Anna Crown, Melanie C. Davies, Ann Ewart, Leighton J. Seal, Arlene Smyth, Helen E. Turner, Lisa Webber, Richard A. Anderson, Richard Quinton   +13 more
wiley   +1 more source

Disorders of puberty and neurodevelopment: A shared etiology?

Annals of the New York Academy of Sciences, Volume 1541, Issue 1, Page 83-99, November 2024.
Disorders of puberty result primarily from dysregulation of gonadotropin‐releasing hormone secretion in the hypothalamus. Studies have uncovered associations between pubertal timing and neurodevelopment. This review discusses the overlap between the brain circuitry controlling puberty and behavior, highlights neurodevelopmental conditions with ...
Jordan E. Read, Alexandru Vasile‐Tudorache, Angel Newsome, María José Lorente, Carmen Agustín‐Pavón, Sasha R. Howard   +5 more
wiley   +1 more source

Gonadotropins and prolactin pituitary reserve in premature thelarche [PDF]

The Journal of Pediatrics, 1977
info:eu-repo/semantics ...
Caufriez, Anne, Wolter, Renee Adrienne, Govaerts, M., L'Hermite, Marc, Robyn, Claude   +4 more
openaire   +2 more sources

Leptin, ghrelin, nesfatin-1, and orexin-A plasma levels in girls with premature thelarche

, 2022
Purpose Reducing the mean age of puberty onset in recent years has crucial public health, clinical, and social implications. This study aimed to evaluate the serum levels of appetite-related peptides (leptin, ghrelin, nesfatin-1, and orexin-A) and ...
Zengin, H. Y., Almasi, N., Rad, N. Heidarzadeh, Koc, N., FİSUNOĞLU, MEHMET, Ucakturk, S. A., Mazman, D. Iskender   +6 more
core   +1 more source

Emergence of the natural history of Myhre syndrome: 47 patients evaluated in the Massachusetts General Hospital Myhre Syndrome Clinic (2016–2023)

American Journal of Medical Genetics Part A, Volume 194, Issue 10, October 2024.
Abstract Myhre syndrome is an increasingly diagnosed ultrarare condition caused by recurrent germline autosomal dominant de novo variants in SMAD4. Detailed multispecialty evaluations performed at the Massachusetts General Hospital (MGH) Myhre Syndrome Clinic (2016–2023) and by collaborating specialists have facilitated deep phenotyping, genotyping and
Angela E. Lin, Eleanor R. Scimone, Robyn P. Thom, Duraisamy Balaguru, T. Bernard Kinane, Peter P. Moschovis, Michael S. Cohen, Weizhen Tan, Cole D. Hague, Katelyn Dannheim, Lynne L. Levitsky, Evelyn Lilly, Daniel V. DiGiacomo, Kara M. Masse, Sarah M. Kadzielski, Claire A. Zar‐Kessler, Leo C. Ginns, Ann M. Neumeyer, Mary K. Colvin, Jack S. Elder, Christopher P. Learn, Hongmei Mou, Kathryn M. Weagle, Karen A. Buch, William E. Butler, Kenda Alhadid, Patricia L. Musolino, Sadia Sultana, Dhrubajyoti Bandyopadhyay, Otto Rapalino, Zachary S. Peacock, Elizabeth L. Chou, Gena Heidary, Aaron T. Dorfman, Shaine A. Morris, James D. Bergin, Jonathan H. Rayment, Lisa A. Schimmenti, Mark E. Lindsay, MGH Myhre Syndrome Study Group, Luisa Paredes Acosta, Jennifer A. Bassetti, Sarah Bowdin, Joy A. Bress, Joseph A. Camarda, Joanne S. Chiu, C. Eduardo Corrales, Gregory Costain, Mary Beth P. Dinulos, Rajiv Devanagondi, Emily S. Doherty, John Dykes, Ann‐Christine Duhaime, Robert F. English, Elizabeth Fieg, Nora D. B. Friedman, Carl P. Garabedian, Samantha Glowacki, Barbara R. Gottlieb, Mary Hope Griffin, Frances J. Hayes, Stephanie R. Hicks, Alicia M. Hinze, Brigette A. Jason, Joel Krier, Kristen Lindgren, Michael Lyons, Adnan Majid, Hannah C. Mannem, Marie McDonald, Vinod Misra, Amy Morgan, Barbara J. Nath, Michele Ploutz, Eloise J. Prijoles, Margaret B. Pulsifer, Alicia M. Quesnel, Farrah Rajabi, Mersedeh Rohanizadegan, Ana Maria Rosales, Holly Rothermel, Edith Schussler, Elizabeth A. Sellars, Joseph Shieh, Stephanie Sherrill, Heidi Taska‐Tench, Matthew Thompson, George E. Tiller, Stephanie E. Vallee, David Viskochil, Stephanie Ware, Rachel C. Whooten, Samuel Yang, Elaine H. Zackai, Dala Zakaria   +94 more
wiley   +1 more source

Serum levels of polybrominated diphenyl ethers in girls with premature thelarche

, 2016
Polybrominated diphenyl ethers (PBDEs) are widely used as flame retardants and have shown endocrine disruption properties in experimental studies. The aim of this study was to investigate the association between the exposure to PBDEs and alterations of ...
Deodati, A, Germani, D, Mancini, FR, Busani, L, Maranghi, F, Puglianiello, A, Cianfarani, S, Baldari, F, Tassinari, R, Sallemi, A, Mantovani, A   +10 more
core   +1 more source

Identification of southern Taiwan genetic variants in thyroid dyshormonogenesis through whole‐exome sequencing

The Kaohsiung Journal of Medical Sciences, Volume 40, Issue 8, Page 744-756, August 2024.
Abstract Thyroid dyshormonogenesis (TDH) is responsible for 15%–25% of congenital hypothyroidism (CH) cases. Pathogenetic variants of this common inherited endocrine disorders vary geographically. Unraveling the genetic underpinnings of TDH is essential for genetic counseling and precise therapeutic strategies.
Ching‐Chao Tsai, Yu‐Ming Chang, Yen‐Yin Chou, Shou‐Yen Chen, Yu‐Wen Pan, Meng‐Che Tsai   +5 more
wiley   +1 more source

Girls with idiopathic central precocious puberty did not display substatial changes in body mass index after treatment with gonadotropin‐releasing hormone analogues

Acta Paediatrica, Volume 113, Issue 7, Page 1602-1611, July 2024.
Abstract Aim To evaluate changes in body mass index (BMI) in girls during and after treatment for idiopathic central precocious puberty (iCPP). Methods We studied 123 girls receiving gonadotropin‐releasing hormone analogue (GnRHa)treatment for iCPP from 2009 to 2019.
Cecilie Skaarup Uldbjerg, Youn‐Hee Lim, Christoffer Højrup Renault, Dorte Hansen, Anders Juul, Elvira Vaclavik Bräuner, Rikke Beck Jensen   +6 more
wiley   +1 more source

Differentiation of Idiopathic Central Precocious Puberty from Premature Thelarche using Principal Component Analysis

, 2023
ContextNonprogressive premature thelarche (PT) is a self-limiting variant of early puberty, while idiopathic central precocious puberty (ICPP) is a disorder that causes progressive development of secondary sexual characteristics and often requires ...
Andre Greger Madsen, Cleemann Wang, Amanda, Katharina M Main, Christiansen, Peter, Rikke Beck Jensen, Main, Katharina M., Amanda Cleemann Wang, Anders Juul, Peter Christiansen, Madsen, Andre Greger, Cleemann, Line Hartvig, Trine Holm Johannsen, Juul, Anders, Casper P Hagen, Hagen, Casper P., Line Hartvig Cleemann, Johannsen, Trine Holm, Jensen, Rikke Beck   +17 more
core   +1 more source