Results 51 to 60 of about 1,479 (196)

Premature thelarche from phenotype to genotype [PDF]

, 2008
Premature thelarche is a benign condition, which has been described as a "variant of puberty". Early breast development is especially prevalent during the first year of life, when the gonadal axis is usually active.
Codner Dujovne, Ethel, Román, Rossana
core  

Predicted Adult Height Remained Normal in Children With Premature Adrenarche Despite Advanced Bone Age

Acta Paediatrica, Volume 114, Issue 12, Page 3258-3266, December 2025.
ABSTRACT Aim Aetiological factors affecting the phenotype of adrenarche are largely unknown. This study investigated the phenotypic variability of premature adrenarche. Methods In this cross‐sectional retrospective registry study, data on 91 mainly Caucasian children diagnosed with premature adrenarche were retrieved from patient records.
Eetu Kanniainen, Jarmo Jääskeläinen, Jani Liimatta   +2 more
wiley   +1 more source

Biocultural synthesis of adolescence: a roadmap to advance the field Synthèse bioculturelle de l'adolescence : une feuille de route pour faire avancer la recherche

Journal of the Royal Anthropological Institute, Volume 31, Issue S2, Page 95-117, September 2025.
Adolescence is an expansive, dynamic period within the life course, covering a broad age range (10‐24 years) and a cascade of biological and cultural changes. However, biocultural approaches to adolescence have been less well developed within existing research compared to child and adult counterparts.
Delaney Glass, Emily Emmott
wiley   +1 more source

Precocious Puberty and Benign Variants in Female Children: Etiology, Diagnostic Challenges, and Clinical Management

Endocrines
Precocious puberty, defined as the onset of secondary sexual characteristics before age 8 in girls, presents a diagnostic challenge in distinguishing between normal variants and pathological conditions requiring intervention.
Roberto Paparella, Arianna Bei, Lorenzo Brilli, Vittorio Maglione, Francesca Tarani, Marcello Niceta, Ida Pucarelli, Luigi Tarani   +7 more
doaj   +1 more source

A de novo KMT2D mutation in a girl with Kabuki syndrome associated with endocrine symptoms: a case report

BMC Medical Genetics, 2018
Background Kabuki syndrome is characterized by distinctive facial features and varying degrees of growth retardation. It leads to malformations in skeletal, urogenital and cardiac structures; moreover, endocrine conditions such as premature thelarche ...
Jung-Eun Moon, Su-Jeong Lee, Cheol Woo Ko   +2 more
doaj   +1 more source

Significance of serum neurokinin B and kisspeptin levels in the differential diagnosis of premature thelarche and idiopathic central precocious puberty.

, 2015
The aim of the present study was to investigate the diagnostic role of serum neurokinin B level and its relationship with kisspeptin and leptin, which are known to be involved in the initiation of pubertal process.
BÖBER, ECE, Calan, ÖZLEM, ABACI, AYHAN, Anik, Ahmet, DÜNDAR, BUMİN NURİ, Catli, Gonul, KÜME, TUNCAY   +6 more
core   +1 more source

Optimizing care for MRKH patients: From malformation screening to uterus transplantation eligibility

Acta Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 3, Page 514-521, March 2025.
38% of women with MRKH syndrome are inadequately explored for associated malformations. Early assessment of ovarian reserve is necessary at diagnosis in women with MRKH syndrome. MRKH syndrome may have a familial and hereditary dimension. Abstract Introduction Mayer‐Rokitansky‐Küster‐Hauser (MRKH) syndrome with utero‐vaginal aplasia is the most severe ...
Auriane Cospain, Ludivine Dion, Maud Bidet, Krystel Nyangoh Timoh, Chloé Quelin, Isis Carton, Alinoe Lavillaureix, Karine Morcel, Paul Rollier, Laurent Pasquier, Bénédicte Nouyou, Sylvie Odent, Daniel Guerrier, Erika Launay, Marc‐Antoine Belaud Rotureau, Mélanie Fradin, Sylvie Jaillard, Vincent Lavoué   +17 more
wiley   +1 more source

Duplication of the Pituitary Gland (DPG)-Plus Syndrome Associated With Midline Anomalies and Precocious Puberty: A Case Report and Review of the Literature

Frontiers in Endocrinology, 2021
Duplication of the pituitary gland (DPG)-plus syndrome is a very rare developmental disorder with few cases described in the literature and characterized by multiple midline and central nervous system malformations.
Giovanni Prezioso, Maddalena Petraroli, Michela Bergonzani, Giusy Davino, Marialuisa Labate, Francesca Ormitti, Marilena Anghinoni, Enrico Sesenna, Susanna Esposito   +8 more
doaj   +1 more source

Associations between birth characteristics, pubertal timing and adult height

Acta Paediatrica, Volume 114, Issue 3, Page 526-535, March 2025.
Abstract Aim This study investigated the association between gestational age and birth size with pubertal timing, measured as peak height velocity, and adult height. Methods This retrospective, population‐based study was conducted in Sweden in 2023. A sub‐group of the 1974 and 1990 GrowUp Gothenburg cohorts was used (n = 4700, 50% males).
Carin Skogastierna, Nazli Kalay, Diana Swolin‐Eide, Anton Holmgren   +3 more
wiley   +1 more source

Metabolic characteristics and pathogenesis of precocious puberty in girls: the role of perfluorinated compounds

BMC Medicine, 2023
Background Precocious puberty (PP) in girls is traditionally defined as the onset of breast development before the age of 8 years. The specific biomarkers of premature thelarche (PT) and central precocious puberty (CPP) girls are uncertain, and little is
Jinxia Wu, Jing Chen, Rong Huang, Hongwei Zhu, Lin Che, Yanyan Lin, Yajie Chang, Guiping Shen, Jianghua Feng   +8 more
doaj   +1 more source