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Clinical Genetics, Volume 110, Issue 1, Page 64-72, July 2026.Biallelic SLC20A1 loss‐of‐function variant causes a previously unrecognized multisystem developmental disorder. We report the first homozygous case presenting with tetralogy of Fallot, renal agenesis, polydactyly, and growth impairment. Transcriptome analysis of patient‐derived fibroblasts suggests significant dysregulation of pathways critical for ...
Eugénie Koumakis +9 more
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Management of premature ventricular complexes
Heart, 2021### Learning objectives Premature ventricular complexes (PVCs) are the most common arrhythmias in daily practice. At the cellular level, ventricular myocytes spontaneously depolarise to create an extrasystole ‘out of sync’ with the cardiac cycle.1 The prevalence depends on the characteristics and comorbidities of the population, the method by which ...
Koji Higuchi, Mandeep Bhargava
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Premature Ventricular Complexes and Premature Ventricular Complex Induced Cardiomyopathy
Current Problems in Cardiology, 2015Presentation, prognosis, and management of premature ventricular complexes (PVCs) vary significantly among patients and depend on PVC characteristics as well as patient comorbidities. Presentation can range from incidental discovery in an asymptomatic patient to debilitating heart failure.
Rakesh, Latchamsetty, Frank, Bogun
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Ethmozine for ventricular premature complexes
The American Journal of Cardiology, 1986Twenty patients with an average of more than 30 ventricular premature complexes (VPCs) per hour were treated with ethmozine. Eighteen had either not responded or had adverse reactions to at least 1 other antiarrhythmic drug. Patients were treated with 200 to 300 mg 3 times daily (8.25 to 11.7 mg/kg) and were followed for up to 6 months.
K, Gear +7 more
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Are those Premature Ventricular Complexes?!
The American Journal of Emergency Medicine, 2014Ventricular parasystole has been known to be a benign rhythm. We present a case of a 53-year-old man with chest pain and ventricular parasystole on electrocardiogram upon initial presentation. He was admitted and found to have normal serial cardiac enzymes and nuclear stress testing. He was discharged home with primary care follow-up. We highlight this
Randeep, Thiara +2 more
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Premature Ventricular Complexes as a Trigger for Ventricular Fibrillation
Revista Española de Cardiología (English Edition), 2010The mechanisms that trigger ventricular fibrillation (VF) are poorly understood. The aim of this study was to analyze the initiation of VF in electrograms stored in implantable cardioverter-defibrillators (ICDs).We analyzed ICD electrograms from patients who had suffered at least one episode of VF.Of 250 patients with ICDs, 13 (10 male and 3 female ...
Juan José, Sánchez Muñoz +6 more
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