Results 101 to 110 of about 554,391 (236)

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

Effect of Flecainide on Multifocal Ectopic Purkinje-Related Premature Contractions in an R814W SCN5A Carrier

JACC: Case Reports
Multifocal ectopic Purkinje-related premature contraction (MEPPC) is an autosomal dominant SCN5A channelopathy characterized by frequent multiform premature ventricular contractions originating from the His-Purkinje system.
Hisham Ahamed, MD, DM, Arun Gopi, MD, DM
doaj   +1 more source

Large Language Model‐Based Localization of Premature Ventricular Contraction Origins: A Retrospective Diagnostic Accuracy Study

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Accurate localization of premature ventricular contraction (PVC) origin from 12‐lead electrocardiography (ECG) is important for procedural planning in catheter ablation. Although convolutional neural network (CNN)‐based models have shown promising diagnostic performance, they require task‐specific training and remain limited in ...
Kazuhisa Matsumoto, Yuya Fujisaki, Syunta Higuchi, Masataka Narita, Wataru Sasaki, Tsukasa Naganuma, Naomichi Tanaka, Daisuke Kawano, Kei Matsumoto, Wataru Yoshino, Yoshifumi Ikeda, Ritsushi Kato, Hitoshi Mori   +12 more
wiley   +1 more source

A Review: Detection of Premature Ventricular Contraction Beat of ECG [PDF]

, 2020
: ECG signal is a periodic signal that gives information about the heart activity. A lot of information about normal and abnormality about the heart can be obtained from the ECG signal. Premature ventricular contractions (PVCs) are the ectopic beats that
Geeta Kanwar, Kiran Dewangan, Naveen Kumar Dewangan   +2 more
core  

First United States Experience With Focal Pulsed‐Field Ablation Using the FARAPOINT Catheter for Refractory Ventricular Tachycardia

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Drug‐refractory ventricular tachycardia (VT) after failed radiofrequency (RF) ablation remains a clinical challenge. Pulsed‐field ablation (PFA) is expanding to ventricular applications, but United States experience with focal pulsed‐field‐only catheters in VT is sparse, and pulsed‐field platforms are not equivalent across ...
Jorge L. Reyes, Rezwan Munshi, Collin Goebel, Venkat Tholakanahalli   +3 more
wiley   +1 more source

The Significance of Premature Ventricular Contractions in the Normal Heart.

The incidence of premature ventricular contractions (PVCs) in a structurally normal heart can result in clinically significant consequences, including PVC-induced cardiomyopathy.
Mihatov, N., Peterson, S.J., Parikh, M.A., Frishman, W.H., Raizada, A.   +4 more
core   +1 more source

Feasibility, Safety, and Efficacy of Pulsed Field Ablation for Ventricular Arrhythmias: Insights From a Large Health System Registry in the United States

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Pulsed field ablation (PFA) is an emerging non‐thermal ablation modality with proven safety in atrial arrhythmia ablation. However, data on its performance for ventricular arrhythmias (VA) remain limited. Objective To evaluate the feasibility, safety, and efficacy of PFA for complex VA in a multicenter real‐world US registry ...
Narut Prasitlumkum, Juan F. Rodriguez‐Riascos, Hema Vemulapalli, Aakash Somappa, Camilo A. Estrada‐Vargas, Olubadewa A. Fatunde, Carlos A. Rojas, Poojan Prajapati, Keerthika Vijayakumar, Suraj Kapa, Duy Nguyen, Samuel Asirvatham, Malini Madhavan, Christopher McLeod, Hicham Z. El Masry, Abhishek J. Deshmukh, Danesh K. Kella, Ammar M. Killu, Siva K. Mulpuru, Mayank Sardana, Luis R. Scott, Alan M. Sugrue, Komandoor Srivathsan   +22 more
wiley   +1 more source

Giants in the cold: Morphological evidence for vascular heat retention in the viscera but not the skeletal muscle of the basking shark (Cetorhinus maximus)

Journal of Fish Biology, EarlyView.
Abstract Fewer than 50 of the over 30,000 extant species of fishes have developed anatomical specializations facilitating endothermy in specific body regions. The plankton‐feeding basking shark (Cetorhinus maximus), traditionally classified as an ectotherm, was recently shown to have regionally endothermic traits such as centralized red muscle (RM ...
C. Antonia Klöcker, Axel Schlindwein, Martin C. Arostegui, Ingrid M. Bruvold, Joel V. Wernström, Montserrat Martin‐Armas, David W. Sims, Nicolas Straube, Andreas Altenburger, Claudia Junge   +9 more
wiley   +1 more source

Recognizing Pathogenic PVCs in Children: A Case of Multifocal Ectopic Purkinje-Related Premature Contractions

Case Reports in Pediatrics
Premature ventricular contractions (PVCs) are a common and benign arrhythmia in children, but they can infrequently be a sign of an underlying cardiac issue that may predispose patients to heart failure and/or sudden cardiac death (SCD).
Lane McLendon, Akash Patel, Peter Aziz, Jeffrey Bennett, Mina K. Chung, Lauren Mientkiewicz, Iqbal El-Assaad   +6 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source