Results 121 to 130 of about 23,948 (277)

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Panoramic voltage‐sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras

The Journal of Physiology, EarlyView.
Abstact figure legend A panoramic 3D optical mapping system was developed, enabling imaging of action potential waves across the entire strongly deforming ventricular surface of beating isolated hearts. The system comprises 12 high‐speed cameras and a soccerball‐shaped imaging chamber with 48 light‐emitting diodes (LEDs).
Shrey Chowdhary, Jan Lebert, Shai Dickman, Mason Manetta, Charles Gordon, Jan Christoph   +5 more
wiley   +1 more source

May Fever Trigger Ventricular Fibrillation? [PDF]

, 2005
The clinical precipitants of ventricular fibrillation (VF) remain poorly understood. Clinical factors such as hypoxemia, acidosis or electrolyte imbalance, drug-related toxicity, autonomic nervous system disorders as well as viral myocarditis have been ...
Pasquié, Jean Luc
core   +1 more source

Catheter Ablation of Ventricular Premature Contractions Originating From RVOT With Interruption of the Inferior Vena Cava—A Case Report

Annals of Noninvasive Electrocardiology
Ventricular premature contractions (VPC) originating from right ventricular outflow tract is the most common type of ventricular arrhythmias in clinic settings, which can be effectively cured by catheter ablation.
Liang Xiong, Jinzhu Hu, Dandan Wang, Juan Hua, Qi Chen   +4 more
doaj   +1 more source

Long QT Syndrome Type 5 With Coexisting KCNE1 and RYR2 Variants: A Diagnostic Ambiguity

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Long QT syndrome (LQTS) predisposes to syncope and sudden cardiac death. Type 5 LQTS, linked to KCNE1 variants, is rare. A teenage female presented with recurrent syncope. ECG showed QTc 485 ms. Genetic testing identified KCNE1 and RYR2 variants. Beta‐blockers and ICD prevented events.
Mohammad Hossein Nikoo, Hossein Fatemian, Amir Hossein Hassani, Mehrdad Rabiee Rad, Sara Mostafavi   +4 more
wiley   +1 more source

Resistant to Ablation, Responsive to Hydroquinidine: Precision Medicine Guides Recovery in MEPPC Syndrome Cardiomyopathy

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
We report a case of MEPPC syndrome presenting with severe dilated cardiomyopathy due to a pathogenic SCN5A p.Arg814Trp variant. Genetic diagnosis enabled precision pharmacotherapy with hydroquinidine, which suppressed multifocal Purkinje‐origin ectopy resistant to catheter ablation and led to marked improvement in left ventricular function.
Jonathan L. Ciofani, Hariharan Raju, Malcolm Anastasius   +2 more
wiley   +1 more source

Efficacy of Fixed Low‐Power Long‐Duration Radiofrequency Ablation of Ventricular Arrhythmias Originating From the Left Ventricular Summit

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
Efficacy and safety of a fixed low‐power, long‐duration radiofrequency catheter ablation of ventricular arrhythmias originating from the left ventricular summit. ABSTRACT Background Radiofrequency catheter ablation (RFCA) of ventricular arrhythmias originating from the left ventricular summit (LVS‐VAs) remains challenging.
Takuro Masuda, Koji Nakagawa, Satoshi Kawada, Tomofumi Mizuno, Akira Ueoka, Saori Asada, Masakazu Miyamoto, Nobuhiro Nishii, Kazufumi Nakamura, Hiroshi Morita, Shinsuke Yuasa   +10 more
wiley   +1 more source

Feasibility and Safety of High‐Power Settings for Electrical Isolation of the Superior Vena Cava Using a Catheter Capable of Local Impedance and Contact Force Monitoring

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
High‐power superior vena cava isolation using a contact force– and local impedance–sensing catheter achieved safe and consistent first‐pass isolation. Local impedance decreased more rapidly than generator impedance, accurately reflecting effective lesion formation and enabling reliable real‐time assessment in thin SVC myocardium.
Daisuke Kawano, Hitoshi Mori, Kei Matsumoto, Naomichi Tanaka, Tsukasa Naganuma, Wataru Sasaki, Masataka Narita, Kazuhisa Matsumoto, Yoshifumi Ikeda, Kazuo Matsumoto, Ritsushi Kato   +10 more
wiley   +1 more source

Electroconvulsive therapy in an older patient with recurrent major depressive disorder and a permanent pacemaker: A case report

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Abstract Background Electroconvulsive therapy (ECT) is highly effective for severe or treatment‐resistant major depressive disorder, including in older adults. In patients with permanent pacemakers, however, ECT may be avoided because of concern about device malfunction or arrhythmia.
Wataru Omori, Narumi Kodaka, Kenichi Oga, Yoshikazu Masuda, Go Okada   +4 more
wiley   +1 more source