Results 101 to 110 of about 614,591 (385)

ABO blood group antigens influence host–microbe interactions and risk of early spontaneous preterm birth

npj Biofilms and Microbiomes
The mechanisms by which vaginal microbiota shape spontaneous preterm birth (sPTB) risk remain poorly defined. Using electronic clinical records data from 74,913 maternities in conjunction with metaxanomic (n = 596) and immune profiling (n = 314) data, we
Katherine E. Mountain, David A. MacIntyre, Yun S. Lee, Virginia Tajadura-Ortega, Anne Dell, Stuart M. Haslam, Gang Wu, Paola Grassi, Ten Feizi, Yan Liu, Wengang Chai, Julian R. Marchesi, Lauren A. Roberts, Denise Chan, Belen Gimeno-Molina, Richard G. Brown, Holly V. Lewis, Alice K. C. Hyde, James Pasint-Magyar, Anna Green, Anna L. David, Jane E. Norman, Sarah J. Stock, Samit Kundu, Sherrianne Ng, Ben Glampson, Erik Mayer, TG Teoh, Vasso Terzidou, Phillip R. Bennett, Lynne Sykes   +30 more
doaj   +1 more source

Community health worker-led household screening and management of neonatal hyperbilirubinemia in rural Bangladesh: a cluster randomized control trial protocol [version 2; peer review: 1 approved, 2 approved with reservations]

Gates Open Research
Background Extreme hyperbilirubinemia leading to neurologic disability and death is disproportionately higher in low- and middle-income countries (LMIC) such as Bangladesh, and is largely preventable through timely treatment.
Mohammod Shahidullah, Md. Mahbubul Hoque, Muhammad Shariful Islam, Vinod K Bhutani, Eric M. Foote, Gary L Darmstadt, Mahbubur Rahman, Farjana Jahan, Tasnim Ahmed, Sarker Masood Parvez, Farzana Yeasmin, Rezaul Hasan, Sk Masum Billah, Shams El Arifeen   +13 more
doaj   +1 more source

Retinopathy of prematurity – etiopathogenesis and treatment

Pediatria i Medycyna Rodzinna, 2017
Retinopathy of prematurity belongs to the group of proliferative retinopathies. It affects preterm infants with very low birth weight, treated with high concentrations of oxygen.
Barbara Rybus-Kalinowska, Sławomir Kwiatkowski, Katarzyna Chojnacka, Jerzy Jochem   +3 more
doaj   +1 more source

Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy. [PDF]

, 2019
MotivationMultiple biological clocks govern a healthy pregnancy. These biological mechanisms produce immunologic, metabolomic, proteomic, genomic and microbiomic adaptations during the course of pregnancy.
Agard, Bruno, Aghaeepour, Nima, Ando, Kazuo, Angst, Martin S, Callahan, Benjamin, Contrepois, Kévin, Culos, Anthony, Darmstadt, Gary L, DiGiulio, Daniel B, Druzin, Maurice L, Ganio, Edward, Gaudilliere, Brice, Gaudilliere, Dyani, Ghaemi, Mohammad Sajjad, Gibbs, Ronald, Han, Xiaoyuan, Lee-McMullen, Brittany, Lehallier, Benoit, Lewis, David B, Maric, Ivana, Mcilwain, David, McNeil, Leslie, Ngo, Thuy TM, Nolan, Garry, Partovi Nia, Vahid, Quaintance, Cecele, Quake, Stephen R, Relman, David A, Robaczewska, Anna, Rosenberg-Hasson, Yael, Shaw, Gary M, Sirota, Marina, Snyder, Michael P, Stanley, Natalie, Stevenson, David K, Tanada, Athena, Tibshirani, Robert, Tingle, Martha, Tsai, Amy, Winn, Virginia D, Wise, Paul, Wong, Ronald J, Wyss-Coray, Tony   +42 more
core   +3 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

SmartPlus: a computer-based image analysis method to predict continuous-valued vascular abnormality index in Retinopathy of Prematurity

International Journal of Retina and Vitreous
Plus disease is characterized by abnormal changes in retinal vasculature of premature infants. Presence of Plus disease is an important criterion for identifying treatment-requiring cases in Retinopathy of Prematurity (ROP).
Sayed Mehran Sharafi, Nazanin Ebrahimiadib, Ramak Roohipourmoallai, Afsar Dastjani Farahani, Marjan Imani Fooladi, Golnaz Gharehbaghi, Elias Khalili Pour   +6 more
doaj   +1 more source

Factors associated with delayed vascular maturation in infants with retinopathy of prematurity not requiring treatment

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2016
Purpose: The aim of this study is to determine risk factors associated with delayed regression of retinopathy of prematurity and prolonged vascular completion in patients not requiring treatment.
Ebru Esen, Selcuk Sizmaz, Hacer Yapicioglu, Ferda Ozlu, Kemal Yar, Ilker Unal, Nihal Demircan   +6 more
doaj   +1 more source

Poor attention rather than hyperactivity/impulsivity predicts academic achievement in very preterm and full-term adolescents [PDF]

, 2013
Background: Very preterm (VP) children are at particular risk for attention deficit/hyperactivity disorder (ADHD) of the inattentive subtype. It is unknown whether the neurodevelopmental pathways to academic underachievement are the same as in the ...
Achenbach, D. Wolke, Esser, Grissemann, J. Jaekel, Jaekel, Johnson, Kaufman, Melchers, Müller, P. Bartmann, Riegel, Rutter, Schubert, Stigler, Wolke, Wolke   +16 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Emerging biomarkers for the diagnosis of severe neonatal infections applicable to low-resource settings [PDF]

Journal of Global Health, 2011
More than 500 000 children die each year in low resource settings due to serious neonatal infections. Better diagnostics that can be utilized in these settings to identify infected infants has the potential to significantly reduce neonatal deaths and ...
Thor A. Wagner , Courtney A. Gravett , Sara Healy , Viju Soma , Janna C. Patterson , Michael G. Gravett , Craig E. Rubens   +6 more
doaj