Results 11 to 20 of about 609,293 (383)

Prostaglandin F2α requires activation of calcium-dependent signalling to trigger inflammation in human myometrium

Frontiers in Endocrinology, 2023
IntroductionPreterm birth is one of the major causes of neonatal morbidity and mortality across the world. Both term and preterm labour are preceded by inflammatory activation in uterine tissues.
Lucia Riaposova, Lucia Riaposova, Sung Hye Kim, Sung Hye Kim, Aylin C. Hanyaloglu, Lynne Sykes, Lynne Sykes, Lynne Sykes, David A. MacIntyre, David A. MacIntyre, Phillip R. Bennett, Phillip R. Bennett, Vasso Terzidou, Vasso Terzidou, Vasso Terzidou   +14 more
doaj   +1 more source

Direct on-swab metabolic profiling of vaginal microbiome host interactions during pregnancy and preterm birth

Nature Communications, 2021
Here, the authors apply DESI-MS, a sample preparation-free, direct on-swab mass spectrometry analytical tool, to profile the cervicovaginal metabolome of two independent cohorts of pregnant women and, combined with matched metataxonomic and immuno ...
Pamela Pruski, Gonçalo D. S. Correia, Holly V. Lewis, Katia Capuccini, Paolo Inglese, Denise Chan, Richard G. Brown, Lindsay Kindinger, Yun S. Lee, Ann Smith, Julian Marchesi, Julie A. K. McDonald, Simon Cameron, Kate Alexander-Hardiman, Anna L. David, Sarah J. Stock, Jane E. Norman, Vasso Terzidou, T. G. Teoh, Lynne Sykes, Phillip R. Bennett, Zoltan Takats, David A. MacIntyre   +22 more
doaj   +1 more source

Vaginal Microbiota, Genital Inflammation and Extracellular Matrix Remodelling Collagenase: MMP-9 in Pregnant Women With HIV, a Potential Preterm Birth Mechanism Warranting Further Exploration

Frontiers in Cellular and Infection Microbiology, 2021
BackgroundPregnant women living with HIV infection (PWLWH) have elevated rates of preterm birth (PTB) in which HIV and cART are implicated. PWLWH also have a high prevalence of adverse vaginal microbiota, which associate with genital tract inflammation ...
Charlotte-Eve S. Short, Charlotte-Eve S. Short, Rachael A. Quinlan, Rachael A. Quinlan, Xuan Wang, Veronica Georgiana Preda, Veronica Georgiana Preda, Ann Smith, Ann Smith, Julian R. Marchesi, Julian R. Marchesi, Yooni S. Lee, Yooni S. Lee, David A. MacIntyre, David A. MacIntyre, Phillip R. Bennett, Phillip R. Bennett, Graham P. Taylor, Graham P. Taylor   +18 more
doaj   +1 more source

15-Deoxy-Delta-12,14-prostaglandin J2 modulates pro-labour and pro-inflammatory responses in human myocytes, vaginal and amnion epithelial cells

Frontiers in Endocrinology, 2022
BackgroundPrematurity is the leading cause of childhood death under the age of five. The aetiology of preterm birth is multifactorial; however, inflammation and infection are the most common causal factors, supporting a potential role for ...
Zahirrah BM. Rasheed, Zahirrah BM. Rasheed, Yun S. Lee, Yun S. Lee, Sung H. Kim, Sung H. Kim, Tg Teoh, Tg Teoh, Tg Teoh, David A. MacIntyre, David A. MacIntyre, Phillip R. Bennett, Phillip R. Bennett, Lynne Sykes, Lynne Sykes, Lynne Sykes   +15 more
doaj   +1 more source

Qualitative Assessment of the Quality of Care for Preterm, Low Birth Weight, and Sick Newborns in Ethiopia

Health Services Insights, 2021
This study assesses the quality of care for preterm, low birth weight (LBW), and sick newborns across the public health care system levels in 3 regions of Ethiopia.
Solomie Jebessa, James A Litch, Kirsten Senturia, Tedros Hailu, Amaha Kahsay, Kemal A Kuti, Eskinder Wolka, Alula M Teklu, Wendemaghen Gezahegn   +8 more
doaj   +1 more source

Long-term consequences of prematurity

Cleveland Clinic journal of medicine, 2020
Due to a shortened period of in utero organ development, premature infants are at higher risk of chronic respiratory, cardiac, renal, and endocrine system disorders later in life.
Cristina I. Pravia, M. Benny
semanticscholar   +1 more source

Referral systems for preterm, low birth weight, and sick newborns in Ethiopia: a qualitative assessment

BMC Pediatrics, 2020
Background A responsive and well-functioning newborn referral system is a cornerstone to the continuum of child health care; however, health system and client-related barriers negatively impact the referral system.
Alula M. Teklu, James A. Litch, Alemu Tesfahun, Eskinder Wolka, Berhe Dessalegn Tuamay, Hagos Gidey, Wondimye Ashenafi Cheru, Kirsten Senturia, Wendemaghen Gezahegn, And the Every Preemie–SCALE Ethiopia Implementation Research Collaboration Group   +9 more
doaj   +1 more source

Lactobacillus-Depleted Vaginal Microbiota in Pregnant Women Living With HIV-1 Infection Are Associated With Increased Local Inflammation and Preterm Birth

Frontiers in Cellular and Infection Microbiology, 2021
BackgroundPregnant women living with HIV-1 infection (PWLWH) have an elevated risk of preterm birth (PTB) of unknown aetiology, which remains after successful suppression of HIV.
Charlotte-Eve S. Short, Charlotte-Eve S. Short, Charlotte-Eve S. Short, Richard G. Brown, Richard G. Brown, Rachael Quinlan, Rachael Quinlan, Rachael Quinlan, Yun S. Lee, Ann Smith, Julian R. Marchesi, Julian R. Marchesi, Julian R. Marchesi, Robin Shattock, Phillip R. Bennett, Phillip R. Bennett, Graham P. Taylor, Graham P. Taylor, Graham P. Taylor, David A. MacIntyre   +19 more
doaj   +1 more source

Microcephaly and macrocephaly. A study on anthropometric and clinical data from 308 subjects [PDF]

, 2019
Head circumference is the auxological parameter that most correlates with developmental anomalies in childhood. Head circumference (HC) two standard deviations (SD) below or above the mean defines microcephaly and macrocephaly, respectively.
Corsello G., Mancuso G., Martorana C., Montante C., Notarbartolo V., Piro E., Schierz I. A. M., Vanella V.   +7 more
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Neonatal Cortical Auditory Evoked Potentials Are Affected by Clinical Conditions Occurring in Early Prematurity [PDF]

, 2015
Purpose: Cortical auditory evoked potentials may serve as an early indicator of developmental problems in the auditory cortex. The aim of the study was to determine the effect on neonatal cortical auditory processing of clinical conditions occurring in ...
Bisiacchi, Patrizia, Cainelli, Elisa, Cappellari, Ambra, Ermani, Mario, Sartori, Stefano, Suppiej, Agnese   +5 more
core   +1 more source