Results 11 to 20 of about 225,404 (337)

Proteome-wide prediction of bacterial carbohydrate-binding proteins as a tool for understanding commensal and pathogen colonisation of the vaginal microbiome

npj Biofilms and Microbiomes, 2021
Bacteria use carbohydrate-binding proteins (CBPs), such as lectins and carbohydrate-binding modules (CBMs), to anchor to specific sugars on host surfaces.
François Bonnardel , Stuart M. Haslam, Anne Dell, Ten Feizi, Yan Liu, Virginia Tajadura-Ortega, Yukie Akune, Lynne Sykes, Phillip R. Bennett, David A. MacIntyre, Frédérique Lisacek, Anne Imberty   +11 more
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N-glycosylation of cervicovaginal fluid reflects microbial community, immune activity, and pregnancy status

Scientific Reports, 2022
Human cervicovaginal fluid (CVF) is a complex, functionally important and glycan rich biological fluid, fundamental in mediating physiological events associated with reproductive health. Using a comprehensive glycomic strategy we reveal an extremely rich
Gang Wu, Paola Grassi, David A. MacIntyre, Belen Gimeno Molina, Lynne Sykes, Samit Kundu, Cheng-Te Hsiao, Kay-Hooi Khoo, Phillip R. Bennett, Anne Dell, Stuart M. Haslam   +10 more
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Assessment of feasibility and acceptability of family-centered care implemented at a neonatal intensive care unit in India

BMC Pediatrics, 2021
Background A family-centered care (FCC) parent participation program that ensures an infant is not separated from parents against their will was developed for the caring of their small or sick newborn at a neonatal intensive care unit (NICU) in Delhi ...
Arti Maria, James A. Litch, Maria Stepanchak, Enisha Sarin, Rashmi Wadhwa, Harish Kumar   +5 more
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Very Preterm Children Gut Microbiota Comparison at the Neonatal Period of 1 Month and 3.5 Years of Life

Frontiers in Microbiology, 2022
Prematurity is a risk factor for dysbiosis of the gut microbiota due to particular birth conditions and frequent prolonged hospitalization of neonates.
Gaël Toubon, Gaël Toubon, Gaël Toubon, Marie-José Butel, Marie-José Butel, Jean-Christophe Rozé, Patricia Lepage, Johanne Delannoy, Johanne Delannoy, Pierre-Yves Ancel, Pierre-Yves Ancel, Marie-Aline Charles, Julio Aires, Julio Aires, for the EPIFLORE Study Group, Clotilde Rousseau, Joel Dore, Ziad Al Nabhani, Karine Le Roux, Celine Monot, Laetitia MartinMarchand, Melanie Durox, Alexandre Lapillonne, Jean-Charles Picaud, Farid Boudred, Delphine Mitanchez, Valerie Biran, Laurent Storme, Olivier Claris, Gilles Cambonie, Cyril Flamant, Anne Sauret, Odile Dicky, Geraldine Favrais, Jean-Michel Hascoet, Geraldine Gascoin, Gerard Thiriez, Luc Desfrere, Xavier Durrmeyer, Clement Chollat   +39 more
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Separation of Maternal and Newborn Care in US Hospitals: A Systemic Threat to Survival, Health and Well-Being

Health Systems & Reform, 2023
Through greater understanding of past social, cultural, economic, political, scientific and technological forces which shaped our current health systems to separate mothers and newborn infants, we can begin to devise effective approaches to reshape these
Kavya I. Anjur, Gary L. Darmstadt
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15-Deoxy-Delta-12,14-prostaglandin J2 modulates pro-labour and pro-inflammatory responses in human myocytes, vaginal and amnion epithelial cells

Frontiers in Endocrinology, 2022
BackgroundPrematurity is the leading cause of childhood death under the age of five. The aetiology of preterm birth is multifactorial; however, inflammation and infection are the most common causal factors, supporting a potential role for ...
Zahirrah BM. Rasheed, Zahirrah BM. Rasheed, Yun S. Lee, Yun S. Lee, Sung H. Kim, Sung H. Kim, Tg Teoh, Tg Teoh, Tg Teoh, David A. MacIntyre, David A. MacIntyre, Phillip R. Bennett, Phillip R. Bennett, Lynne Sykes, Lynne Sykes, Lynne Sykes   +15 more
doaj   +1 more source

Direct on-swab metabolic profiling of vaginal microbiome host interactions during pregnancy and preterm birth

Nature Communications, 2021
Here, the authors apply DESI-MS, a sample preparation-free, direct on-swab mass spectrometry analytical tool, to profile the cervicovaginal metabolome of two independent cohorts of pregnant women and, combined with matched metataxonomic and immuno ...
Pamela Pruski, Gonçalo D. S. Correia, Holly V. Lewis, Katia Capuccini, Paolo Inglese, Denise Chan, Richard G. Brown, Lindsay Kindinger, Yun S. Lee, Ann Smith, Julian Marchesi, Julie A. K. McDonald, Simon Cameron, Kate Alexander-Hardiman, Anna L. David, Sarah J. Stock, Jane E. Norman, Vasso Terzidou, T. G. Teoh, Lynne Sykes, Phillip R. Bennett, Zoltan Takats, David A. MacIntyre   +22 more
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Prostaglandin F2α requires activation of calcium-dependent signalling to trigger inflammation in human myometrium

Frontiers in Endocrinology, 2023
IntroductionPreterm birth is one of the major causes of neonatal morbidity and mortality across the world. Both term and preterm labour are preceded by inflammatory activation in uterine tissues.
Lucia Riaposova, Lucia Riaposova, Sung Hye Kim, Sung Hye Kim, Aylin C. Hanyaloglu, Lynne Sykes, Lynne Sykes, Lynne Sykes, David A. MacIntyre, David A. MacIntyre, Phillip R. Bennett, Phillip R. Bennett, Vasso Terzidou, Vasso Terzidou, Vasso Terzidou   +14 more
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Qualitative Assessment of the Quality of Care for Preterm, Low Birth Weight, and Sick Newborns in Ethiopia

Health Services Insights, 2021
This study assesses the quality of care for preterm, low birth weight (LBW), and sick newborns across the public health care system levels in 3 regions of Ethiopia.
Solomie Jebessa, James A Litch, Kirsten Senturia, Tedros Hailu, Amaha Kahsay, Kemal A Kuti, Eskinder Wolka, Alula M Teklu, Wendemaghen Gezahegn   +8 more
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Vaginal Microbiota, Genital Inflammation and Extracellular Matrix Remodelling Collagenase: MMP-9 in Pregnant Women With HIV, a Potential Preterm Birth Mechanism Warranting Further Exploration

Frontiers in Cellular and Infection Microbiology, 2021
BackgroundPregnant women living with HIV infection (PWLWH) have elevated rates of preterm birth (PTB) in which HIV and cART are implicated. PWLWH also have a high prevalence of adverse vaginal microbiota, which associate with genital tract inflammation ...
Charlotte-Eve S. Short, Charlotte-Eve S. Short, Rachael A. Quinlan, Rachael A. Quinlan, Xuan Wang, Veronica Georgiana Preda, Veronica Georgiana Preda, Ann Smith, Ann Smith, Julian R. Marchesi, Julian R. Marchesi, Yooni S. Lee, Yooni S. Lee, David A. MacIntyre, David A. MacIntyre, Phillip R. Bennett, Phillip R. Bennett, Graham P. Taylor, Graham P. Taylor   +18 more
doaj   +1 more source