Results 31 to 40 of about 110,311 (309)

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Outcomes at school-age of children born extremely preterm or extremely low birth weight in Victoria, Australia: protocol for the 8–9 years follow-up of the prospective, longitudinal Victorian Infant Collaborative Study (VICS) 2016–2017 cohort

BMJ Open
Introduction Children born extremely preterm (EP; <28 weeks’ gestation) and/or extremely low birth weight (ELBW; <1000 g) are at increased risk of difficulties across a range of neurodevelopmental domains and respiratory outcomes long term.
Lex W Doyle, Jeanie L Y Cheong, Anjali Haikerwal, Peter Anderson, Rosemarie Boland, Margaret Charlton, Noni Davis, lex Doyle, Julianne Duff, Leah Hickey, Elisha Josev, Bronwyn Novella, Joy Olsen, Gehan Roberts, Alicia Spittle, Penelope Stevens, Anne-marie Turner, Alice Stewart, Emily Johnston, Julie Chen, Marissa Clark, Elizabeth Noble, Joy E Olsen, Evelyne Muggli, Niranjan Abraham, Rheanna Mainzer, Lauren Pigdon, Tugba Alarcon-Martinez, Rheanna M Mainzer, Lindsay Zhou, Tania Woods, Thi-Nhu-Ngoc Nguyen, Cassidy Du Berry, Luke Howlin, Samuel Axford, Micki Goh, Amanda Kwong, Dianne Malcolm, Kerry-Ann O’Connor, Sarah Ojiambo, Sarah Rostron   +40 more
doaj   +1 more source

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Classifying retinopathy of prematurity [PDF]

, 2017
Knowing how to classify retinopathy of prematurity is essential as it provides information on the prognosis and guides decision making about screening and ...
Subhadra Jalali, Dan Weaver, Andrea Molinari   +2 more
core  

Identification and characterisation of vaginal bacteria-glycan interactions implicated in reproductive tract health and pregnancy outcomes

Nature Communications
Lactobacillus displacement from the vaginal microbiome associates with adverse health outcomes and is linked to increased risk of preterm birth. Glycans mediate bacterial adhesion events involved in colonisation and infection.
Virginia Tajadura-Ortega, Wengang Chai, Lauren A. Roberts, Yibing Zhang, Antonio Di Maio, Alexiane C. Decout, Benedita A. Pinheiro, Angelina S. Palma, Gian De Nicola, Lucia Riaposova, Belen Gimeno-Molina, Yun S. Lee, Hongzhi Cao, Vladimir Piskarev, Yukie Akune, Tiago R. D. Costa, Himani Amin, Lynne Sykes, Phillip R. Bennett, Julian R. Marchesi, Ten Feizi, Yan Liu, David A. MacIntyre   +22 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Risk factors of preterm delivery in HIV infected pregnant women receiving zidovudine for the prevention of perinatal HIV

, 2009
Aim: Several studies have shown that preterm delivery, a primary cause of perinatal mortality and morbidity, is more frequent in HIV‐positive women. This study aimed to determine factors associated with prematurity in HIV‐infected women and identify ...
Pornkitprasarn, Witaya, Lallemant, Marc, Jungpichanvanich, Sivaporn, Mary, Jean-Yves, Wannapira, Wiroj, Traisathit, Patrinee, Matanasarawut, Wanmanee, Gomuthbutra, Vorapin, Le Coeur, Sophie, Tantanarat, Sudanee   +9 more
core   +1 more source

Astrocyte-derived vascular endothelial growth factor stabilizes vessels in the developing retinal vasculature [PDF]

, 2010
Vascular endothelial growth factor (VEGF) plays a critical role in normal development as well as retinal vasculature disease. During retinal vascularization, VEGF is most strongly expressed by not yet vascularized retinal astrocytes, but also by retinal ...
Michael B. Powner, Powner, MB, Scott, A., Clarkin, C., Gandhi, P, Scott, Andrew, David H Gutmann, Randall S Johnson, Fruttiger, Marcus, Gutmann, DH, Johnson, RS, David H. Gutmann, Gutmann David H., Gutmann, David H., Powner Michael B., Gandhi, P., Scott Andrew, Clarkin Claire, Ferrara, N., Gandhi Pranita, Napoleone Ferrara, Johnson Randall S., Clarkin, Claire, Scott, A, Pranita Gandhi, Ferrara, Napoleone, Michael B Powner, Fruttiger Marcus, Gandhi, Pranita, Powner, Michael B., Ferrara Napoleone, Andrew Scott, Powner, M. B., Connon, Che John, Ferrara, N, Claire Clarkin, Clarkin, C, Fruttiger, M., Johnson, R.S., Gutmann, D.H., Fruttiger, M, Randall S. Johnson, Johnson, Randall S., Marcus Fruttiger   +43 more
core   +3 more sources

Glycomics of cervicovaginal fluid from women at risk of preterm birth reveals immuno-regulatory epitopes that are hallmarks of cancer and viral glycosylation

Scientific Reports
During pregnancy the immune system needs to maintain immune tolerance of the foetus while also responding to infection, which can cause premature activation of the inflammatory pathways leading to the onset of labour and preterm birth.
Gang Wu, Paola Grassi, Belen Gimeno Molina, David A. MacIntyre, Lynne Sykes, Phillip R. Bennett, Anne Dell, Stuart M. Haslam   +7 more
doaj   +1 more source

The incidence of retinopathy of prematurity in a tertiary care center in Turkey

Beyoglu Eye Journal, 2018
INTRODUCTION[|]The objective of our study was to determine the incidence of retinopathy of prematurity in our hospital, which gives tertiary health services.[¤]METHODS[|]In this retrospective study, the medical files of the infants, who were born before ...
Dilbade Yıldız Ekinci, Sadik Etka Bayramoglu, Asli Deger Vural   +2 more
doaj   +1 more source