Results 41 to 50 of about 101,131 (312)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Risk factors of preterm delivery in HIV infected pregnant women receiving zidovudine for the prevention of perinatal HIV

, 2009
Aim: Several studies have shown that preterm delivery, a primary cause of perinatal mortality and morbidity, is more frequent in HIV‐positive women. This study aimed to determine factors associated with prematurity in HIV‐infected women and identify ...
Pornkitprasarn, Witaya, Lallemant, Marc, Jungpichanvanich, Sivaporn, Mary, Jean-Yves, Wannapira, Wiroj, Traisathit, Patrinee, Matanasarawut, Wanmanee, Gomuthbutra, Vorapin, Le Coeur, Sophie, Tantanarat, Sudanee   +9 more
core   +1 more source

Glycomics of cervicovaginal fluid from women at risk of preterm birth reveals immuno-regulatory epitopes that are hallmarks of cancer and viral glycosylation

Scientific Reports
During pregnancy the immune system needs to maintain immune tolerance of the foetus while also responding to infection, which can cause premature activation of the inflammatory pathways leading to the onset of labour and preterm birth.
Gang Wu, Paola Grassi, Belen Gimeno Molina, David A. MacIntyre, Lynne Sykes, Phillip R. Bennett, Anne Dell, Stuart M. Haslam   +7 more
doaj   +1 more source

Association among gestational diabetes mellitus, periodontitis and prematurity: a cross-sectional study

Archives of Endocrinology and Metabolism, 2022
Objective: Gestational diabetes mellitus (GDM) causes maternal and infant morbidity. Periodontitis is associated with adverse pregnancy outcomes. The aim of this study was to evaluate periodontal status, prematurity and associated factors in pregnant ...
Carla Andreotti Damante, Gerson Aparecido Foratori Junior, Paula de Oliveira Cunha, Carlos Antonio Negrato, Silvia Helena Carvalho Sales-Peres, Mariana Schutzer Ragghianti Zangrando, Adriana Campos Passanezi Sant’Ana   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Premature ejaculation

Indian Journal of Urology, 2007
Premature ejaculation (PE) is a common male sexual disorder. Recent normative data suggests that men with an intravaginal ejaculatory latency time (IELT) of less than 1 minute have "definite" PE, while men with IELTs between 1 and 1.5 minutes have "probable" PE.
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Retinopathy of Prematurity [PDF]

Journal of the Royal Army Medical Corps, 1987
This paper briefly reviews Retinopathy of Prematurity. It outlines the present incidence and risk factors, summarises the ophthalmic pathology and suggests a scheme of ophthalmic examination and management.
openaire   +4 more sources

Does field of view matter? Assessing its impact on Plus disease diagnosis in retinopathy of prematurity

International Journal of Retina and Vitreous
Purpose This study investigates the impact of field of view (FOV) on the diagnosis of Plus disease in retinopathy of prematurity (ROP), focusing on how different FOVs influence expert assessments.
Sayed Mehran Sharafi, Mobina Amanollahi, Nazanin Ebrahimiadib, Mohammad Hossein Nowroozzadeh, Marjan Imani Fooladi, Fatemeh Bazvand, Nader Mohammadi, Mohammad Bagher Rajabi, Hamid Riazi-Esfahani, Elias Khalili Pour   +9 more
doaj   +1 more source

Expanding vaginal microbiome pangenomes via a custom MIDAS database reveals Lactobacillus crispatus accessory genes associated with cervical dysplasia

mSystems
The vaginal microbiome plays a central role in reproductive health. Vaginal microbiome dysbiosis is associated with many adverse reproductive health outcomes, but most studies have focused on associations at the species level.
Claire A. Dubin, Chunyu Zhao, Katherine S. Pollard, Tomiko Oskotsky, Jonathan L. Golob, Marina Sirota   +5 more
doaj   +1 more source