Results 51 to 60 of about 101,131 (312)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Retinopathy of Prematurity [PDF]

open access: yes, 2014
Retinopathy of prematurity is one of the most significant reasons of the childhood blindness in developing countries due to the rising numbers of preterm deliveries and improved neonatal care.
Kadir Kırboğa   +2 more
core  

Optical Coherence Tomography and Wide-Field Fluorescein Angiography in Retinopathy of Prematurity

open access: yes, 2017
The advent and adaptation of many imaging modalities promise to revolutionize our understanding of retinopathy of prematurity (ROP) by improving the detection, diagnosis, and monitoring of response to treatment of this disease.
Cynthia A. Toth   +7 more
core   +1 more source

Automated diagnosis of plus disease in retinopathy of prematurity using quantification of vessels characteristics

open access: yesScientific Reports
The condition known as Plus disease is distinguished by atypical alterations in the retinal vasculature of neonates born prematurely. It has been demonstrated that the diagnosis of Plus disease is subjective and qualitative in nature.
Sayed Mehran Sharafi   +5 more
doaj   +1 more source

Retinopathy of prematurity and its association with neonatal factors

open access: yesBangabandhu Sheikh Mujib Medical University Journal, 2017
Retinopathy of prematurity is considered as an important cause of blindness. This prospective study was undertaken to document the frequency and the associated factors of retinopathy of prematurity among 97 preterm newborn weighing
Mohammod Shahidullah   +6 more
doaj   +1 more source

A data-driven health index for neonatal morbidities

open access: yesiScience, 2022
Summary: Whereas prematurity is a major cause of neonatal mortality, morbidity, and lifelong impairment, the degree of prematurity is usually defined by the gestational age (GA) at delivery rather than by neonatal morbidity.
Davide De Francesco   +20 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Caffeine is a risk factor for osteopenia of prematurity in preterm infants: a cohort study

open access: yesBMC Pediatrics, 2018
Background Caffeine, the most commonly used medication in Neonatal Intensive Care Units, has calciuric and osteoclastogenic effects. Methods To examine the association between the cumulative dose and duration of therapy of caffeine and osteopenia of ...
Ebtihal Ali   +5 more
doaj   +1 more source

Assessment of Neonatal Care Standard by the Predictive Model for Retinopathy of Prematurity Based on Weight Gain

open access: yesActa Clinica Croatica, 2023
Care of extremely premature infants is in constant need for evaluation and progress. WINROP, a predictive model based on weight gain, has been developed to reduce the number of stressful examinations for retinopathy for prematurity.
Ana Čolić   +2 more
doaj   +1 more source

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