Results 51 to 60 of about 153,808 (291)

Retinopathy of prematurity and its association with neonatal factors

Bangabandhu Sheikh Mujib Medical University Journal, 2017
Retinopathy of prematurity is considered as an important cause of blindness. This prospective study was undertaken to document the frequency and the associated factors of retinopathy of prematurity among 97 preterm newborn weighing
Mohammod Shahidullah, Arjun Chandra Dey, Firoz Ahmed, Ismat Jahan, Sanjoy Kumer Dey, Nuzhat Choudhury, M. A. Mannan   +6 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Automated diagnosis of plus disease in retinopathy of prematurity using quantification of vessels characteristics

Scientific Reports
The condition known as Plus disease is distinguished by atypical alterations in the retinal vasculature of neonates born prematurely. It has been demonstrated that the diagnosis of Plus disease is subjective and qualitative in nature.
Sayed Mehran Sharafi, Nazanin Ebrahimiadib, Ramak Roohipourmoallai, Afsar Dastjani Farahani, Marjan Imani Fooladi, Elias Khalili Pour   +5 more
doaj   +1 more source

A data-driven health index for neonatal morbidities

iScience, 2022
Summary: Whereas prematurity is a major cause of neonatal mortality, morbidity, and lifelong impairment, the degree of prematurity is usually defined by the gestational age (GA) at delivery rather than by neonatal morbidity.
Davide De Francesco, Yair J. Blumenfeld, Ivana Marić, Jonathan A. Mayo, Alan L. Chang, Ramin Fallahzadeh, Thanaphong Phongpreecha, Alex J. Butwick, Maria Xenochristou, Ciaran S. Phibbs, Neda H. Bidoki, Martin Becker, Anthony Culos, Camilo Espinosa, Qun Liu, Karl G. Sylvester, Brice Gaudilliere, Martin S. Angst, David K. Stevenson, Gary M. Shaw, Nima Aghaeepour   +20 more
doaj   +1 more source

Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial [PDF]

, 2019
Background Infections acquired in hospital are an important cause of morbidity and mortality in very preterm infants. Several small trials have suggested that supplementing the enteral diet of very preterm infants with lactoferrin, an antimicrobial ...
Ainsworth, S, Bartle, D, Batra, D, Baum, A, Berrington, J, Bowler, U, Boyle, E, Bradburn, M, Clarke, P, Cooke, R, Craig, S, Dorling, J, ELFINTI Grp, Ellis, S, Embleton, N, Ewer, A, Garg, S, Geethanath, R, Gibson, D, Gowda, G, Griffiths, J, Gupta, R, Halliday, H, Heath, P, Hellier, J, Holder, G, Hutchison, F, Janakiraman, S, Jenkins, P, Johnson, K, Johnson, M, Juszczak, E, Kennea, N, King, A, Kumar, Y, Ledwidge, M, Linsell, L, Mactier, H, Manjunatha, CM, Mannix, P, Matthes, J, McGuire, W, Millar, M, Murray, D, Oddie, S, Ohadike, P, Partlett, C, Patel, M, Peters, C, Piling, E, Quine, D, Reynolds, P, Roehr, C, Scorrer, T, Story, I, Subhedar, N, Vailcutz, R, Vargova, M, Vasu, V, Yates, H   +59 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Caffeine is a risk factor for osteopenia of prematurity in preterm infants: a cohort study

BMC Pediatrics, 2018
Background Caffeine, the most commonly used medication in Neonatal Intensive Care Units, has calciuric and osteoclastogenic effects. Methods To examine the association between the cumulative dose and duration of therapy of caffeine and osteopenia of ...
Ebtihal Ali, Cheryl Rockman-Greenberg, Michael Moffatt, Michael Narvey, Martin Reed, Depeng Jiang   +5 more
doaj   +1 more source

Assessment of Neonatal Care Standard by the Predictive Model for Retinopathy of Prematurity Based on Weight Gain

Acta Clinica Croatica, 2023
Care of extremely premature infants is in constant need for evaluation and progress. WINROP, a predictive model based on weight gain, has been developed to reduce the number of stressful examinations for retinopathy for prematurity.
Ana Čolić, Nenad Vukojević, Sonja Anić Jurica   +2 more
doaj   +1 more source

Attention and regional gray matter development in very preterm children at age 12 years [PDF]

, 2017
Objectives: This study examines the selective, sustained, and executive attention abilities of very preterm (VPT) born children in relation to concurrent structural magnetic resonance imaging (MRI) measures of regional gray matter development at age 12 ...
Bora, Samudragupta, Lean, Rachel E, Melzer, Tracy R, Watts, Richard, Woodward, Lianne J   +4 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source