Results 151 to 160 of about 51,527 (295)

Pegvaliase Treatment for Adolescents With Phenylketonuria: A Multi‐Site Study

JIMD Reports, Volume 67, Issue 2, March 2026.
ABSTRACT Phenylketonuria (PKU) is an inherited metabolic disorder causing elevated phenylalanine (Phe) levels and neurocognitive impairment if left untreated. While dietary therapy remains the treatment standard, adherence declines during adolescence. Pegvaliase, an injectable enzyme therapy approved for adults > 18 years in the United States, lowers ...
Suzanne Hollander, Briana Valli, Erika Vucko, Melissa Lah, Amarilis Sanchez‐Valle, Brittany M. Murray, Amy Kritzer, Stephanie Sacharow   +7 more
wiley   +1 more source

THE EFFECT OF HIGH DOSE AND LOW DOSE PREGABALIN AS PREMEDICATION ON PREOPERATIVE ANXIETY AND SEDATION LEVELS

, 2021
Ayman Zafar, Kulsoom Farhat, Mobasher Ahmed Saeed, Waqar Aslam Khan, Shabana Ali, Nausheen Ata   +5 more
openalex   +2 more sources

Efficacy and Safety of DNV3 (a Lymphocyte‐activation Gene 3–blocking Antibody) Combined With Toripalimab and Chemotherapy in Advanced Melanoma: An Open‐label, Single‐arm Clinical Trial

MedComm, Volume 7, Issue 3, March 2026.
This investigator‐initiated trial demonstrates that LAG‐3/PD‐1 dual blockade (DNV3 + toripalimab) combined with chemotherapy achieves a 44.4% overall response rate (ORR) in advanced melanoma, showing particular efficacy in anti‐PD‐(L)1‐resistant patients (42.9% ORR, 7.36‐month median PFS), treatment‐naïve mucosal melanoma (50.0% ORR), and those with ...
Jing Lin, Lizhu Chen, Ling Chen, Dingyi Wang, Yuping Lu, Huishan Zhang, Ping Chen, Wei Yan, Zuoxiang Xiao, Yu Chen   +9 more
wiley   +1 more source

A STUDY OF INFLUENCE OF DEXMEDETOMIDINE PREMEDICATION ON CHANGES IN INTRAOCULAR PRESSURE FOLLOWING ADMINISTRATION OF SUCCINYLCHOLINE AND ENDOTRACHEAL INTUBATION

, 2018
Payaswinee Payaswinee, Deepesh Gupta, Saubhagya Agarwal   +2 more
openalex   +1 more source

UK Paramedic Rapid Sequence Intubation...Is it viable? [PDF]

This report details the indications and drug requirements of Rapid Sequence Intubation (RSI), then proceeds to discuss the literature and evidence surrounding RSI with a view to answering the question: Can UK Paramedics perform RSI? And more importantly,
Gubbins, Karen
core  

Evaluation of Laryngeal Mask Airway Use in Pediatric Bronchoscopy: A 10‐Year Retrospective Study

Pediatric Pulmonology, Volume 61, Issue 3, March 2026.
ABSTRACT Background The effectiveness and safety of laryngeal mask airway (LMA) use in pediatric flexible bronchoscopy remains insufficiently documented, particularly regarding age‐specific outcomes. This study aimed to evaluate LMA compared to mask ventilation during pediatric flexible bronchoscopy, focusing on oxygenation parameters and complications
Yasar Gokhan Gul, Sedat Oktem, Pelin Karaaslan, Tumay Uludag Yanaral   +3 more
wiley   +1 more source

Effect of oral pregabalin premedication on perioperative haemodynamic response and post operative analgesic requirement for patients undergoing laparoscopic cholecystectomy

, 2018
A S Sandhya, H Sahajananda, Vikyath Jain
openalex   +1 more source

Premedication with intranasal dexmedetomidine decreases barbiturate requirement in pediatric patients sedated for magnetic resonance imaging: a retrospective study [PDF]

, 2018
Panu Uusalo, Mirjam Lehtinen, Eliisa Löyttyniemi, Tuula Manner, Mika Scheinin, Teijo I. Saari   +5 more
openalex   +1 more source

Novel Combined Approach for Vision‐Preserving Iridociliary Tumour Excision in a Small‐Breed Dog: Contralateral Iris Excision With En‐Bloc Scleral Resection

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
• A 2.8 mm corneal paracentesis positioned opposite to the tumour location enabled fine iris scissors insertion for precise excision of tumour‐bearing iris tissue under miotic guidance with pilocarpine 2%. • A fornix‐based conjunctival peritomy 5 mm from the limbus and stepped scleral flap approach allowed circumferential deep scleral incision with 2–3 
Jae‐Ik Kang, Jeong‐Eun Yeom, Kyung‐Mee Park   +2 more
wiley   +1 more source

Linking Canine Teeth Eruption, Testicular Histology and Testosterone Levels as Indicators of Pubertal Maturation in Male Dogs

Anatomia, Histologia, Embryologia, Volume 55, Issue 2, March 2026.
ABSTRACT Puberty in male dogs marks the transition to sexual maturity, characterised by rising testosterone and testicular maturation. While often estimated at 6 months, the absence of birth records frequently complicates age determination. This study evaluated whether permanent canine tooth eruption serves as a reliable, complementary marker for ...
Raúl Rebolledo‐Martínez, Rodrigo López‐Mora, María de la Paz Palacios‐Arellano, Miriam Barradas‐Moctezuma, Deissy Herrera‐Covarrubias, Pedro Paredes‐Ramos, Jorge Manzo, Genaro Alfonso Coria‐Avila   +7 more
wiley   +1 more source