Results 51 to 60 of about 2,552,713 (172)

The brain's functional connectome in young children with prenatal alcohol exposure

NeuroImage: Clinical, 2019
Prenatal alcohol exposure (PAE) can lead to altered brain function and structure, as well as lifelong cognitive, behavioral, and mental health difficulties.
Xiangyu Long, Preeti Kar, Ben Gibbard, Christina Tortorelli, Catherine Lebel   +4 more
doaj   +1 more source

Long‐Term Neurodevelopmental Outcome Following Three Randomized Controlled Trials of Choline in Fetal Alcohol Spectrum Disorder (FASD)

Alcohol, Clinical and Experimental Research, Volume 50, Issue 10, October 2026.
This manuscript describes a 5‐year longitudinal follow‐up study of children with Fetal Alcohol Spectrum Disorders (FASD) who took part in one of three randomized controlled trials of choline supplementation when they were 2.5–5.9 years old. Results demonstrate that early choline supplementation improves long‐term non‐verbal IQ and working memory and ...
Jeffrey R. Wozniak, Judith K. Eckerle, Blake A. Gimbel, Abigail M. Ernst, Mary E. Anthony, Kent A. Tuominen, Erik de Water, Alexandra L. Doughty, Steven H. Zeisel, Michael K. Georgieff   +9 more
wiley   +1 more source

Prenatal Alcohol Exposure and Congenital Heart Defects: Retinoic Acid Deficiency as a Potential Mechanism in Dextro-Type Transposition of the Great Arteries

Pathophysiology
Fetal alcohol spectrum disorder (FASD) is a preventable cause of developmental disabilities linked to prenatal alcohol exposure (PAE). Congenital heart defects (CHDs) are frequently observed in FASD, with a notable association between PAE and dextro-type
Roberto Paparella, Carolina Putotto, Marco Fiore, Fiorenza Colloridi, Paolo Versacci, Mauro Ceccanti, Bruno Marino, Luigi Tarani   +7 more
doaj   +1 more source

Prenatal alcohol exposure and early-life adversity: a translational perspective for dissecting compounding impacts.

, 2023
Commentary: Fetal alcohol spectrum disorder (FASD) describes the wide range of physical, physiological, cognitive, and neurobehavioral deficits associated with prenatal alcohol exposure (PAE; Caputo et al., 2016; Lunde et al., 2016; Mattson et al., 2019).
Holman, Parker J, Raineki, Charlis
core   +1 more source

Does a pint a day affect your child’s pay? The effect of prenatal alcohol exposure on adult outcomes [PDF]

This paper utilizes a Swedish alcohol policy experiment conducted in the late 1960s to identify the impact of prenatal alcohol exposure on educational attainments and labor market outcomes.
Nilsson, J Peter
core   +2 more sources

An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder

Scientific Reports, 2021
Prenatal alcohol exposure (PAE) causes permanent cognitive disability. The enteric microbiome generates microbial-dependent products (MDPs) that may contribute to disorders including autism, depression, and anxiety; it is unknown whether similar ...
Manjot S. Virdee, Nipun Saini, Colin D. Kay, Andrew P. Neilson, Sze Ting Cecilia Kwan, Kaylee K. Helfrich, Sandra M. Mooney, Susan M. Smith   +7 more
doaj   +1 more source

Knowledge as prevention: a cost-effective intervention to reduce prenatal alcohol exposure. [PDF]

BACKGROUND Prenatal alcohol exposure (PAE) remains high despite international guidelines recommending alcohol abstinence during pregnancy. This poses a significant public health concern, as PAE is known to have harmful effects on fetal development and is
O'Rourke, Suzanne, Kuenssberg, Renate, Keating, Orlagh, McDougall, Stewart, Brown, Ruth H   +4 more
core   +2 more sources

Effect of Postnatal Epigallocatechin-Gallate Treatment on Cardiac Function in Mice Prenatally Exposed to Alcohol

Antioxidants, 2023
Prenatal alcohol exposure affects the cardiovascular health of the offspring. Epigallocatechin-3-gallate (EGCG) may be a protective agent against it, but no data are available regarding its impact on cardiac dysfunction.
Vicente Andreu-Fernández, Mariona Serra-Delgado, Laura Almeida-Toledano, Àgueda García-Meseguer, Melina Vieiros, Anna Ramos-Triguero, Concha Muñoz-Lozano, Elisabet Navarro-Tapia, Leopoldo Martínez, Óscar García-Algar, María D. Gómez-Roig   +10 more
doaj   +1 more source

Fetal MRI based brain atlas analysis detects initial in utero effects of prenatal alcohol exposure

, 2023
Prenatal alcohol exposure (PAE) can change the normal trajectory of human fetal brain development and may lead to long-lasting neurodevelopmental changes in the form of fetal alcohol spectrum disorders.
Gregor Kasprian, Kasprian, Gregor Johannes, Elisabeth Krampl-Bettelheim, Langs, Georg, Lisa Bartha-Doering, Schmidbauer, Victor U., Victor U Schmidbauer, Mariana C Diogo, Seidl, Rainer, Rainer Seidl, Krampl-Bettelheim, Elisabeth, Prayer, Daniela, Birgit Pfeiler, Georg Langs, Glatter, Sarah, Taymourtash, Athena, Pfeiler, Birgit, Kienast, Patric, Bartha-Döring, Elisabeth, Stuempflen, Marlene, Sarah Glatter, Schwartz, Ernst, Patric Kienast, Diogo, Mariana C., Ernst Schwartz, Athena Taymourtash, Marlene Stuempflen, Daniela Prayer   +27 more
core   +1 more source

Fetal alcohol spectrum disorders: current issues in awareness, prevention and intervention [PDF]

, 2014
This paper reviews the research and current policy surrounding prenatal alcohol exposure and fetal alcohol spectrum disorders (FASD). Alcohol use during pregnancy is linked to a spectrum of adverse fetal outcomes.
Sara McLean, Stewart McDougall
core