Results 31 to 40 of about 12,404 (141)

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

open access: yesObesity Reviews, EarlyView.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye   +6 more
wiley   +1 more source

Interplay of early-life nutritional programming on obesity, inflammation and epigenetic outcomes [PDF]

open access: yes, 2012
The huge health burden accompanying obesity is not only attributable to inadequate dietary and sedentary lifestyle habits, since a predisposing genetic make-up and other putative determinants concerning easier weight gain and fat deposition have been ...
Campión-Zabalza, J. (Javier)   +3 more
core  

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

open access: yesExperimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

The Impact of External Factors on the Epigenome: In Utero and over Lifetime [PDF]

open access: yes, 2016
Epigenetic marks change during fetal development, adult life, and aging. Some changes play an important role in the establishment and regulation of gene programs, but others seem to occur without any apparent physiological role.
Fernández Fernández, Agustín   +4 more
core   +3 more sources

Impaired angiogenesis in gestational diabetes is linked to succinate/SUCNR1 axis dysregulation in late gestation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Gestational Diabetes Mellitus (GDM) impacts on succinate metabolism and angiogenesis in the umbilical cord endothelium. (Left Panel) Succinate levels increase in both maternal and fetal circulation at delivery, with higher concentrations observed in GDM pregnancies compared to controls during late gestation.
Sergiy Klid   +13 more
wiley   +1 more source

Genotype‐By‐Environment Interaction for Scrotal Circumference in Young Nellore Bulls Under Pasture and Feedlot Conditions and Its Correlation With Days to Calving

open access: yesAnimal Genetics, Volume 57, Issue 2, April 2026.
ABSTRACT Scrotal circumference (SC) is a key reproductive indicator in beef cattle and an important predictor of male puberty and correlated female fertility. In this study, we evaluated young Nellore bulls raised under combinations of pasture and feedlot environments and modeled SC using a “double” reaction norm model. Additive genetic variance for SC
Christiane A. Silva   +4 more
wiley   +1 more source

Causal Relationship Between Neurotrophins and Normal Pressure Hydrocephalus: Insights From a Bidirectional Two‐Sample Mendelian Randomization Study

open access: yesBrain and Behavior, Volume 16, Issue 4, April 2026.
This Mendelian randomization study reveals that normal pressure hydrocephalus (NPH) causally leads to lower levels of the neurotrophins CNTF and GDNF. This finding provides new genetic evidence for the role of neurotrophic factors in NPH, suggesting potential avenues for further research into prevention and treatment strategies.
Tao Xu   +4 more
wiley   +1 more source

Testing the Integrated Theory of Health Behaviour Change for Postpartum Weight Management [PDF]

open access: yes, 2011
Aim.  This is a report of a correlational study to test the Integrated Theory of Health Behaviour Change within the context of postpartum weight self‐management including the impact of race/ethnicity and weight classification. Background.
Brondino, Michael J   +3 more
core   +2 more sources

Heat‐Induced Toxicants: Sensory Appeal Distracts Consumers' Attention From Potential Toxicological Risks of Thermally Processed Foods

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
The central paradox of thermal processing of foods. (A) The application of heat (e.g., frying, baking, grilling) to food initiates complex chemical reactions, most notably the Maillard reaction and thermal degradation of protein, lipids, and carbohydrate. (B) These reactions create a desirable sensory experience characterized by enticing aromas, golden‐
Joachim Dotto Matondo   +1 more
wiley   +1 more source

A common cause for a common phenotype : the gatekeeper hypothesis in fetal programming [PDF]

open access: yes, 2011
Copyright © 2011 Elsevier Ltd.
Gambling, L   +5 more
core   +1 more source

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