Editorial:Spotlight on Japan - chemical sciences 2023 [PDF]
Yuji Nishiuchi, Yuji Nishiuchi
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Therapeutic Potential of Extracts from Macaranga tanarius (MTE) in Diabetic Nephropathy [PDF]
Diabetic nephropathy is a complication of diabetes that leads to end-stage kidney disease and is a major health burden worldwide. Prenylflavonoid compounds extracted from Macaranga tanarius (MTE) exhibit anti-inflammation, anti-oxidant, and anti ...
Yung-Chien Hsu +5 more
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Dose-Dependent Protective and Inductive Effects of Xanthohumol on Oxidative DNA Damage in Saccharomyces cerevisiae [PDF]
The effect of xanthohumol, a prenylflavonoid isolated from the hop plant (Humulus lupulus L.), on Saccharomyces cerevisiae DNA oxidative damage and viability was evaluated. Yeast cultures under oxidative stress, induced by H2O2, displayed stronger growth
Daniel O. Carvalho +3 more
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Prenylflavonoids isolated from Epimedii Herba show inhibition activity against advanced glycation end-products [PDF]
Introduction: As inhibitors of advanced glycation end products (AGEs), such as pyridoxamine, significantly inhibit the development of retinopathy and neuropathy in rats with streptozotocin-induced diabetes, treatment with AGE inhibitors is believed to be
Keisuke Nakashima +5 more
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Phytochemical characterization and pharmacological evaluation of aerial and root parts of Dalea pazensis Rusby [Fabaceae] [PDF]
BackgroundThe Dalea genus [Fabaceae] is rich in bioactive flavonoids and contains underexplored species, such as Dalea pazensis Rusby, with potential for antifungal and dermatological applications.PurposeConsidering the limited knowledge available on D ...
Mariana Andrea Peralta +9 more
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A Combination of Polymethoxyflavones from Citrus sinensis and Prenylflavonoids from Humulus lupulus Counteracts IL-1β-Induced Differentiated Caco-2 Cells Dysfunction via a Modulation of NF-κB/Nrf2 Activation [PDF]
We here investigated the anti-inflammatory activity of a polymethoxylated flavone-containing fraction (PMFF) from Citrus sinensis and of a prenylflavonoid-containing one (PFF) from Humulus lupulus, either alone or in combination (MIX). To this end, an in
Ignazio Restivo +17 more
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Craft Beer Produced by Immobilized Yeast Cells with the Addition of Grape Pomace Seed Powder: Physico-Chemical Characterization and Antioxidant Properties [PDF]
The aim of this study was to produce and to characterize craft beer fermented by immobilized yeast cells with the addition of Prokupac grape pomace seed powder (2.5% and 5%), to obtain a beer enriched with phenolic compounds and improved sensory ...
Danijel D. Milinčić +9 more
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Morusin as a drug candidate: opportunities, limitations, and the path toward clinical translation [PDF]
Prenylflavonoids are widespread in plants, which are considered valuable sources of natural polyphenolic compounds with isoprenyl groups, including flavones, flavanones, chalcones and aurones. Among the notable prenylated flavonoids, morusin-a prenylated
Hany N. Azzam +11 more
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Induction of ROS and DNA damage-dependent senescence by icaritin contributes to its antitumor activity in hepatocellular carcinoma cells [PDF]
Context: Icaritin (ICT), a prenylflavonoid derivative extracted from the Epimedium (Berberidaceae) genus, has been identified to exhibit antitumor effect in hepatocellular carcinoma (HCC) cells by inducing apoptosis.
Shikang Wang +7 more
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Macaranga tanarius (MT) and Syzygium jambos (SJ) are pharmacologically reported to have anti-oxidant, anti-inflammatory, and anti-diabetic effects, and can be neuroprotective agents.
Mira Syahfriena Amir Rawa +4 more
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