Dose-Dependent Protective and Inductive Effects of Xanthohumol on Oxidative DNA Damage in Saccharomyces cerevisiae [PDF]
The effect of xanthohumol, a prenylflavonoid isolated from the hop plant (Humulus lupulus L.), on Saccharomyces cerevisiae DNA oxidative damage and viability was evaluated. Yeast cultures under oxidative stress, induced by H2O2, displayed stronger growth
Daniel O. Carvalho +3 more
doaj +5 more sources
Deciphering a novel RP-HPLC based bioanalytical method for Estimation of xanthohumol in rat plasma and postbiotic-based nanostructured lipid carriers [PDF]
The study aimed to establish an accurate, specific, linear, precise, and robust method for quantifying xanthohumol loaded in nanostructured lipid carriers using the liquid chromatography.
Bushra Bashir +11 more
doaj +2 more sources
Glycosylation of Xanthohumol by Fungi
A screening test on 29 microorganisms for transformation of xanthohumol led to the selection of twelve fungal strains. One of them, Beauveria bassiana AM278, converted xanthohumol into a glucosylated derivative. This product was identified as xanthohumol 4’-O-β-D-4’’’- methoxyglucopyranoside.
Agnieszka Bartmańska +2 more
exaly +3 more sources
Xanthohumol is the principal prenylated flavonoid of the female inflorescences of the hop plant. In recent years, various beneficial xanthohumol effects including anti-inflammatory, antioxidant, hypoglycemic activities, and anticancer effects have been ...
Ralf Weiskirchen +2 more
exaly +3 more sources
Proteomic antibacterial characterization of flavonoid xanthohumol and probiotic Clostridium butyricum on pathogenic Clostridioides difficile [PDF]
Background The management of dysbiotic gut microbiota in Clostridioides difficile infection has attracted increasing scholarly attention. The development of therapeutic agents with low toxicity, derived from both the flavonoid xanthohumol and the short ...
Shenkun Wei +9 more
doaj +2 more sources
Xanthohumol ameliorates diabetic kidney disease through suppression of renal fibrosis by regulating SNHG10/miR-378b [PDF]
ContentDiabetic kidney disease (DKD), commonly termed diabetic nephropathy (DN), is characterized by oxidative stress and renal tubular epithelial cells apoptosis driven by high glucose (HG).ObjectiveTo explore the protective effects and underlying ...
Jian Hao, Hui Li, Weimin Yu
doaj +2 more sources
Purification of Spent Hop Cone (Humulus lupulus L.) Extract with Xanthohumol Using Mesoporous Superparamagnetic Iron Oxide Nanoparticles [PDF]
(1) Background: Over 90% of hop crops are currently used in beer production, with a small part used in the cosmetics and pharmaceutical industries. Spent hops as a waste product contain one of the strongest antioxidants, xanthohumol. The aim of the study
Natalia Żuk +4 more
doaj +2 more sources
Effects of Natural Ingredient Xanthohumol on the Intestinal Microbiota, Metabolic Profiles and Disease Resistance to Streptococcus agalactiae in Tilapia Oreochromis niloticus [PDF]
Streptococcus agalactiae (SA) is a severe prevalent pathogen, resulting in high morbidity and mortality in the global tilapia industry. With increasing bacterial resistance to antibiotics, alternative strategies are urgently needed.
Aiguo Huang +7 more
doaj +2 more sources
Reversing metabolic dysregulation in farnesoid X receptor knockout mice via gut microbiota modulation. [PDF]
The farnesoid X receptor (FXR), expressed in the liver and in the small intestine, is a key regulator of glucose and lipid metabolism. Its pharmacological modulation is explored as a potential treatment for obesity-related metabolic impairments.
Ines Leila Paraiso +6 more
doaj +2 more sources
Hop constituents with estrogenic effects and their exploitation.
This review deals with a survey of hop substances with estrogenic effect, their structures, biosynthesis and their fate during brewing process.Main attention was done to 8-prenylnaringenin and its precursor - desmethylxanthohumol.
Michal KUŘEC +2 more
doaj +4 more sources

