Results 41 to 50 of about 5,333 (223)

Adipocyte effects of xanthohumol

The FASEB Journal, 2008
Adipocyte hypertrophy may constitute an initiating factor in the inflammatory state that occurs in obesity. Adipocyte size is largely determined by the rate of proliferation and differentiation of adipocytes. The aim of this work was to study the effects of xanthohumol (XN), a flavonoid from hops ( Humulus ...
Vanda Mendes, Rosário Monteiro, Conceição Calhau, Isabel Azevedo   +3 more
openaire   +1 more source

Strong Antimicrobial Effects of Xanthohumol and Beta-Acids from Hops against Clostridioides difficile Infection In Vivo

Antibiotics, 2021
Clostridioides (C.) difficile is an important causative pathogen of nosocomial gastrointestinal infections in humans with an increasing incidence, morbidity, and mortality. The available treatment options against this pathogen are limited.
Radek Sleha, Vera Radochova, Alexander Mikyska, Milan Houska, Radka Bolehovska, Sylva Janovska, Jaroslav Pejchal, Lubica Muckova, Pavel Cermak, Pavel Bostik   +9 more
doaj   +1 more source

Fundamentals and Health Benefits of Xanthohumol, a Natural Product Derived from Hops and Beer

Natural Product Communications, 2009
In recent years, there has been a growing interest in phenolic compounds and their presumed role in the prevention of various degenerative diseases, such as cancer and cardiovascular diseases.
Paulo J. Magalhães, Daniel O. Carvalho, José M. Cruz, Luís F. Guido, Aquiles A. Barros   +4 more
doaj   +1 more source

Synthesis and Antiproliferative Activity of Minor Hops Prenylflavonoids and New Insights on Prenyl Group Cyclization

Molecules, 2018
Synthesis of minor prenylflavonoids found in hops and their non-natural derivatives were performed. The antiproliferative activity of the obtained compounds against some human cancer cell lines was investigated. Using xanthohumol isolated from spent hops
Jarosław Popłoński, Eliza Turlej, Sandra Sordon, Tomasz Tronina, Agnieszka Bartmańska, Joanna Wietrzyk, Ewa Huszcza   +6 more
doaj   +1 more source

GABA_A Receptor-Mediated Sleep-Promoting Effect of Saaz–Saphir Hops Mixture Containing Xanthohumol and Humulone

Molecules, 2021
Hops contain flavonoids that have sedative and sleep-promoting activities such as α-acid, β-acid, and xanthohumol. In this study, the sleep-enhancing activity of a Saaz–Saphir hops mixture was measured.
Byungjick Min, Yejin Ahn, Hyeok-Jun Cho, Woong-Kwon Kwak, Hyung Joo Suh, Kyungae Jo   +5 more
doaj   +1 more source

Emerging role of nuclear factor erythroid 2-related factor 2 in the mechanism of action and resistance to anticancer therapies [PDF]

, 2019
Nuclear factor E2-related factor 2 (NRF2), a transcription factor, is a master regulator of an array of genes related to oxidative and electrophilic stress that promote and maintain redox homeostasis. NRF2 function is well studied in in vitro, animal and
Deeni, Yusuf Y., Kankia, Ibrahim H., Langdon, Simon P., Paramasivan, Poornima   +3 more
core   +3 more sources

Hopfeninhaltsstoffe für die Neuroregeneration

Julius-Kühn-Archiv, 2023
Humulus lupulus L. - Hopfen - ist eine seit langem verwendete Arzneipflanze. Die traditionelle Anwendung bei Schlaflosigkeit hängt mit den Bittersäuren zusammen, welche den Hopfen auch für die Brauindustrie wertvoll machen.
Urmann, Corinna, Bieler, Lara, Able, Theresa, Huber, Veronika, Kirchinger, Michael, Aigner, Ludwig, Couillard-Despres, Sebastien, Riepl, Herbert   +7 more
doaj   +1 more source

The integrative bioinformatics approaches to predict the xanthohumol as anti-breast cancer molecule: Targeting cancer cells signaling PI3K and AKT kinase pathway

Frontiers in Oncology, 2022
BackgroundBreast cancer is the most common type of cancer in women, and vast research is being conducted throughout the world for the treatment of this malignancy by natural products using various computational approaches.
Kartikey Kumar Gupta, Kamal Kant Sharma, Harish Chandra, Himalaya Panwar, Nitin Bhardwaj, Najla A. Altwaijry, Aisha A. Alsfouk, Zodwa Dlamini, Obaid Afzal, Abdulmalik S. A. Altamimi, Shahanavaj Khan, Shahanavaj Khan, Shahanavaj Khan, Abhay Prakash Mishra   +13 more
doaj   +1 more source

Chalcones and Dihydrochalcones Augment TRAIL-Mediated Apoptosis in Prostate Cancer Cells [PDF]

, 2010
Chalcones and dihydrochalcones exhibit chemopreventive and antitumor activity. TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) is a natural endogenous anticancer agent.
Almasan, Andrzej Paradysz, Bogdan Mazur, Dicarlo, Dimmock, D’Archivio, Ewelina Szliszka, Ferguson, Go, Han, Horinaka, Hsu, Lee, Shankar, Szliszka, Szliszka, Szliszka, Szliszka, Szliszka, Tang, Wojciech Krol, Wu, Yoshida, Zenon P. Czuba, Zhang   +24 more
core   +2 more sources

Application of diffusion-edited and solvent suppression 1H NMR to the direct analysis of markers in valerian-hop liquid herbal products [PDF]

, 2016
This is the peer reviewed version of the following article: Jose M. Prieto, Maria Mellinas-Gomez, Mire Zloh, ‘Application of diffusion-edited and solvent suppression 1H-NMR to the direct analysis of markers in valerian-hop liquid herbal products ...
American Herbal Pharmacopoeia, Barjat, Booker, European Directorate for the Quality of Medicines and HealthCare, Gilard, Goppel, Hoek, Houghton, Khatib, Lazarowych, Nilsson, Otto, Politi, Politi, Viel   +14 more
core   +1 more source