Results 51 to 60 of about 5,333 (223)

Xanthohumol improved cognitive flexibility in young mice [PDF]

open access: yesBehavioural Brain Research, 2014
The protein palmitoylation cycle has been shown to be important for protein signaling and synaptic plasticity. Data from our lab showed a change in the palmitoylation status of certain proteins with age. A greater percentage of the NMDA receptor subunits GluN2A and GluN2B, along with Fyn and PSD95 proteins, were palmitoylated in the old mice.
Daniel R, Zamzow   +5 more
openaire   +2 more sources

Simultaneous determination of prenylflavonoids and isoflavonoids in hops and beer by HPLC-DAD method: Study of green hops homogenate application in the brewing process.

open access: yesKvasný průmysl, 2013
Polyphenolic substances belonging to prenylflavonoids and isoflavonoids groups have health-promoting effects and protecting effects against many civilization diseases . They act as antioxidants, have anti-cancer, anti-microbial, anti-inflammatory effects,
Marie JURKOVÁ   +3 more
doaj   +1 more source

Buck Wheat: Nutritional, Bioactive Characteristics, Health Benefits, and Side Effects

open access: yesFuture Postharvest and Food, EarlyView.
ABSTRACT Micronutrient deficits have resulted from an over‐reliance on a small number of cereal crops for food security. The agricultural sector faces severe sustainability issues due to the rapid growth of the world's population and sudden climatic changes.
Momina Farooq   +2 more
wiley   +1 more source

Beyond “you are what you eat”: Unlocking gut microbiota‐mediated biotransformation of dietary phytochemicals

open access: yesiMetaOmics, EarlyView.
The “efficacy paradox” of phytochemicals, low bioavailability yet significant health benefits, is associated with gut microbiota, which biotransforms dietary precursors into bioactive metabolites, enabling systemic effects. Thus, health outcomes of diet depend not just on intake “the rainbow”, but on gut microbial metabolism, redefining “you are what ...
Peng Yang, Ren‐You Gan
wiley   +1 more source

Xanthohumol alleviates oxidative stress and impaired autophagy in experimental severe acute pancreatitis through inhibition of AKT/mTOR

open access: yesFrontiers in Pharmacology, 2023
Severe acute pancreatitis (SAP) is a lethal gastrointestinal disorder, yet no specific and effective treatment is available. Its pathogenesis involves inflammatory cascade, oxidative stress, and autophagy dysfunction.
Yaru Huangfu   +13 more
doaj   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

open access: yesPhytochemical Analysis, EarlyView.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek   +3 more
wiley   +1 more source

Interaction and structure-activity relationship characterization of hop-derived α-acid/xanthohumol and protein Z

open access: yesShipin yu jixie
ObjectiveTo investigate the interaction mechanism and structure-activity relationship between two hop-derived small molecules different in structure (α-acid and xanthohumol) and barley protein Z.Methodsα-acid and protein Z with high purity are prepared ...
WANG Limin   +3 more
doaj   +1 more source

Investigation of properties of biologically active substances and their content in cones of ukrainian hop varieties

open access: yesAgricultural Science and Practice, 2018
Introduction. According to the data of foreign studies, prenyl fl avonoids and bitter substances of hop have signifi cant antioxidant, antiviral, antimicrobial, anti-infl ammatory and anti-carcinogenic properties. Methods.
L. Protsenko   +4 more
doaj   +1 more source

Xanthohumol Attenuated Inflammation and ECM Degradation by Mediating HO-1/C/EBPβ Pathway in Osteoarthritis Chondrocytes

open access: yesFrontiers in Pharmacology, 2021
Osteoarthritis (OA) is the most frequent and disabling disease in developed countries. The progressive degeneration of articular cartilage characterized as thinner and erosive. Inflammation is well-known to be involved in OA development.
Ming Zhang   +6 more
doaj   +1 more source

Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa. [PDF]

open access: yes, 2009
RNA isolated from the glands of a Delta(9)-tetrahydrocannabinolic acid (THCA)-producing strain of Cannabis sativa was used to generate a cDNA library containing over 100 000 expressed sequence tags (ESTs).
Dixon, Richard A   +8 more
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