Results 21 to 30 of about 744 (163)

Prenylflavonoids from Flourensia fiebrigii

Phytochemistry, 2007
Three compounds: (2S)-8-(3''-methylbut-2''-enyl)-7,3',4'-trihydroxyflavanone, (2S)-8-(3''-methyl-4''-hydroxy-but-2''-enyl)-7,3',4'-trihydroxyflavanone and (2S)-8-(3''-methyl-4''-hydroxy-but-2''-enyl)-5,3',4'-trihydroxy-7-methoxyflavanone, along with five previously known compounds, were isolated from the aerial parts of Flourensia fiebrigii.
Uriburu Monasterio, Maria Laura, Gil, Roberto Ricardo, Sosa, Virginia Estela, de la Fuente, Juana Rosa   +3 more
openaire   +3 more sources

Icaritin, an inhibitor of beta-site amyloid cleaving enzyme-1, inhibits secretion of amyloid precursor protein in APP-PS1-HEK293 cells by impeding the amyloidogenic pathway [PDF]

PeerJ, 2019
Background Icaritin (ICT) is a prenylflavonoid derivative from Epimedium brevicornum Maxim. ICT has been shown to have neuroprotective effects. We investigate how ICT affects secretion of amyloid precursor protein (APP). Methods We exposed APP-PS1-HEK293
Fei Feng, Yuanyuan Li, Nanqu Huang, Yong Luo   +3 more
doaj   +2 more sources

Icaritin Induces Anti-tumor Immune Responses in Hepatocellular Carcinoma by Inhibiting Splenic Myeloid-Derived Suppressor Cell Generation

Frontiers in Immunology, 2021
Recent studies have demonstrated that splenic extramedullary hematopoiesis (EMH) is an important mechanism for the accumulation of myeloid-derived suppressor cells (MDSCs) in tumor tissues, and thus contributes to disease progression.
Huimin Tao, Huimin Tao, Mingyu Liu, Mingyu Liu, Yuan Wang, Shufeng Luo, Yongquan Xu, Bin Ye, Limin Zheng, Kun Meng, Lian Li   +10 more
doaj   +1 more source

Detecting beer intake by unique metabolite patterns [PDF]

, 2016
Evaluation of the health related effects of beer intake is hampered by the lack of accurate tools for assessing intakes (biomarkers). Therefore, we identified plasma and urine metabolites associated with recent beer intake by untargeted metabolomics and ...
Bech, Lene, Dragsted, Lars Ove, Gürdeniz, Gözde, Jensen, Morten Georg, Lund, Erik, Meier, Sebastian   +5 more
core   +2 more sources

Prenylflavonoids counteract ovariectomy-induced disturbances in rats

Journal of Functional Foods, 2021
The aim of the study was to investigate in animal model the influence of hops prenylflavonoids on hot flashes and bone loss. Xanthohumol (XN) and hop prenylflavonoids extract (HOP) restored twenty-four-hour variability of tail skin temperature in ovariectomized rats.
Beata Nowak, Agnieszka Matuszewska, Jarosław Popłoński, Anna Nikodem, Jarosław Filipiak, Magdalena Tomanik, Wojciech Dziewiszek, Maciej Danielewski, Kinga Belowska-Bień, Marek Kłobucki, Sandra Sordon, Diana Jędrzejuk, Ireneusz Ceremuga, Małgorzata Trocha, Tomasz Sozański, Tomasz Piasecki, Marek Bolanowski, Ewa Huszcza, Adam Szeląg   +18 more
openaire   +3 more sources

Revaluation of Waste Yeast from Beer Production [PDF]

, 2013
Brewing yeast is an important waste product from beer production. The valorification of slurry yeast mainly consists of separation of vitamins and important nitrogen compounds.
Coldea, Teodora, Mudura, Elena, Socaci, Sonia, Suruceanu, Nicoleta   +3 more
core   +5 more sources

Antispasmodic Activity of Prenylated Phenolic Compounds from the Root Bark of Morus nigra

Molecules, 2019
Black mulberry is a widely acknowledged ancient traditional medicine. Its extract and constituents have been reported to exert various bioactivities including antimicrobial, hypotensive, analgesic etc. effects.
Zoofishan Zoofishan, Norbert Kúsz, Attila Csorba, Gábor Tóth, Judit Hajagos-Tóth, Anna Kothencz, Róbert Gáspár, Attila Hunyadi   +7 more
doaj   +1 more source

The HMI™ module: a new tool to study the host-microbiota interaction in the human gastrointestinal tract in vitro [PDF]

, 2014
Background: Recent scientific developments have shed more light on the importance of the host-microbe interaction, particularly in the gut. However, the mechanistic study of the host-microbe interplay is complicated by the intrinsic limitations in ...
Bracke, Marc, De Ryck, Tine, Derycke, Lara, Harmsen, Hermie, Hennebel, Tom, Marzorati, Massimo, Pieters, Jan, Pinheiro, Iris, Possemiers, Sam, Sadaghian Sadabad, Mehdi, Van De Wiele, Tom, Van den Abbeele, Pieter, Vanhoecke, Barbara, Verstraete, Willy   +13 more
core   +5 more sources

Arsenic thiolation and the role of sulfate-reducing bacteria from the human intestinal tract [PDF]

, 2014
BACKGROUND: Arsenic (As) toxicity is primarily based on its chemical speciation. Although inorganic and methylated As species are well characterized in terms of metabolism and formation in the human body, the origin of thiolated methylarsenicals is still
Alava, Pradeep, Cornejo Rubin De Celis, Sergio, Du Laing, Gijs, Van de Wiele, Tom, Zekker, Ivar   +4 more
core   +3 more sources

Disposition of hop prenylflavonoids in human breast tissue [PDF]

Molecular Nutrition & Food Research, 2010
AbstractHop‐derived products may contain xanthohumol (XN), isoxanthohumol (IX), and the potent phytoestrogen 8‐prenylnaringenin (8‐PN). To evaluate the potential health effects of these prenylflavonoids on breast tissue, their concentration, nature of metabolites, and biodistribution were assessed and compared with 17β‐estradiol (E2) exposure.
Selin, Bolca, Jinghu, Li, Dejan, Nikolic, Nathalie, Roche, Phillip, Blondeel, Sam, Possemiers, Denis, De Keukeleire, Marc, Bracke, Arne, Heyerick, Richard B, van Breemen, Herman, Depypere   +10 more
openaire   +2 more sources