Activation of proestrogens from hops by human intestinal bacteria: conversion of isoxanthohumol into the potent phytoestrogen 8-prenylnaringenin [PDF]
, 2007 Hop, an essential ingredient in beer, contains different prenylflavonoids, among which 8-prenylnaringenin (8-PN) would be the most potent phytoestrogen currently known.
Possemiers, Sam
core +1 more source
Effect of hops extract supplementation on cardiovascular risk markers in obese and diabetic postmenopausal women [PDF]
, 2022 [eng] Obesity and type 2 diabetes mellitus, often termed diabesity, are two of the most prevalent diseases worldwide, and are often deemed as the world’s largest epidemic.
March, Molly Anna
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Development of an Analytical Method for Quantification of Endocrine-Disrupting Phytoestrogenic Compounds in Estuarine Environment Using UHPLC-MS/MS [PDF]
, 2018 Endocrine disrupting compounds (EDCs) are nearly ubiquitous in the daily lives of individuals around the globe. Phytoestrogenic polyphenols (PEPPs, also known as phytoestrogens) represent a subgroup of EDCs.
Qi, Jingyi
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Engineering Escherichia coli towards the production of prenylflavonoids
, 2021 [Excerpt] Background Prenylflavonoids are flavonoid-derived compounds that are characterized by the presence of a lipophilic prenylated side-chain in the flavonoid skeleton. These compounds have several recognized biological activities, namely estrogenic, antioxidant, anti-inflammatory and anticancer.
Gomes, Daniela +2 more
openaire +1 more source
TRAIL-Sensitizing Effects of Flavonoids in Cancer. [PDF]
Int J Mol Sci, 2023 Luiz-Ferreira A +5 more
europepmc +1 more source
Nature’s brewery to bedtime: The Role of hops in GABAA receptor modulation and sleep promotion [PDF]
Insomnia, a prevalent health challenge, often requires pharmacological interventions to improve sleep onset, maintenance, and quality. Benzodiazepines and Z-drugs, like other positive modulators, enhance the inhibitory effects of gamma-aminobutyric acid (
Benkherouf, Ali Yasser
core
BIOACTIVE SUBSTANCES FROM HOPS – XANTHOHUMOL [PDF]
, 2009 Xanthohumol (3’-[3,3–dimetyl allyl]-2’,4’,4-trihydroxy-6’-methoxychalcone) is the principal prenylated flavonoid of the female inflorescences of the hop plant (‘ Humulus lupulus L.), an ingredient of beer.
Mudura, Elena
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A Novel Prenylflavonoid Icariside I Ameliorates Estrogen Deficiency-Induced Osteoporosis via Simultaneous Regulation of Osteoblast and Osteoclast Differentiation. [PDF]
ACS Pharmacol Transl Sci, 2023 Chen C +13 more
europepmc +1 more source
Investigation of molecular interactions of prenylflavonoids at GABAA receptor subtypes [PDF]
, 2019 Prenylated flavonoids derived from Hops (Humulus lupulus) activate the γ-aminobutyric acid (GABA) type A receptors through positive and negative modulation.
Somborac, Tamara
core
BREWER`S SPENT HOP POLYPHENOLS CHARACTERIZATION AND INDUSTRIAL EXPLOITATION [PDF]
, 2017 Beer industry generates important amounts of by-products. Last decade forced industrials to improve waste management and studies focused the exploitation of these by-products in ones with added value.
COLDEA, Teodora Emilia +5 more
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