Results 191 to 200 of about 647,081 (351)

HIV Preexposure Prophylaxis Utilization and Reasons for Never Using Preexposure Prophylaxis Among Transfeminine Persons in the United States: Findings From the Transgender Women's Internet Survey and Testing (TWIST) Study. [PDF]

Open Forum Infect Dis
Islek D, Sanchez T, Baral S, Caldwell JA, Glick JL, Lucas I, Sarkar S, Ragone L, de Ruiter A, Valentine-Graves M, Winter S, Vannappagari V.   +11 more
europepmc   +1 more source

Genome‐Wide Association Study Reveals Insect Genetics and Microbial Symbiont Effects on Susceptibility of Diaphorina citri to the Citrus Greening Pathogen, Candidatus Liberibacter Asiaticus

Advanced Science, EarlyView.
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu, Qingcui He, Zeyue Lin, Shixuan Huang, Zichun Zhong, Pingyang Zhu, Mengge Gao, Luyao Zhao, Han Jin, Guiting Wu, Gurr M. Geoff, Qunxin Han, Rui Pang   +12 more
wiley   +1 more source

Oral preexposure prophylaxis use and the risk of bacterial sexually transmitted infections and HIV among African women: A prospective observational cohort study. [PDF]

PLoS Med
Mukasa D, Kinuthia J, Meisner A, Matemo D, Schaafsma T, Morton J, Wandera C, Budiawan E, Kemuto V, Irine C, Odhiambo S, Bii M, Oduor B, Achieng E, Oyombra T, Ukah UV, Mugwanya KK, FP Plus Project Team.   +17 more
europepmc   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Pre-exposure prophylaxis against HIV infection among male population under perceived risk of sexually transmitted infections in Vojvodina, Serbia: a cross-sectional study on knowledge and attitudes. [PDF]

Front Reprod Health
Vuković V, Ilić S, Ristić M, Bassioni-Stamenić F, Zobenica R, Rajčević S, Cvetićanin R, Stanišić O, Medić T, Jandrić Kočić J, Bohucki N, Popov S, Simić D, Milosavljević Z, Brkić S, Marić D.   +15 more
europepmc   +1 more source

Understanding Demand for PrEP and Early Experiences of PrEP Use Among Young Adults in Rural Kenya and Uganda: A Qualitative Study

Aids and Behavior, 2020
C. Camlin, Catherine A Koss, Monica Getahun, Lawrence Owino, Harriet Itiakorit, Cecilia Akatukwasa, Irene Maeri, Robert Bakanoma, Anjeline Onyango, Frederick Atwine, J. Ayieko, J. Kabami, F. Mwangwa, Mucunguzi Atukunda, A. Owaraganise, D. Kwarisiima, N. Sang, E. Bukusi, M. Kamya, M. Petersen, C. Cohen, E. Charlebois, D. Havlir   +22 more
semanticscholar   +1 more source

BCR::ABL1‐Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B‐ALL Cells to Enhancer‐Targeting Drugs

Advanced Science, EarlyView.
Ng et al. show that the BCR::ABL1 kinase that drives the lymphoid leukemia Ph+B‐ALL modulates enhancer function by coopting signaling‐inducible transcription factors such as MYC, STAT5, and ETV5. BCR::ABL1 thereby promotes the transcriptional program driving and defining this leukemia and renders Ph+B‐ALL cells hypersensitive to enhancer‐inhibiting ...
Han Leng Ng, Trudy Lee Glaser, Jintao Zhu, Mark E. Robinson, Kadriye N. Cosgun, Valeriya Malysheva, Ozgen Deniz, Nicholas T. Crump, Kaiyue Helian, Andrew J. Innes, Richard Burt, Li Sun, George John, Haibin Zhou, Atsunori Kaneshige, Longchuan Bai, Shaomeng Wang, Mikhail Spivakov, Markus Müschen, Niklas Feldhahn   +19 more
wiley   +1 more source

Implementación de la Profilaxis pre-exposición al VIH en Colombia

Interdisciplinary Journal of Epidemiology and Public Health, 2023
Hector Fabio Mueses-Marín, Ximena Galindo-Orrego, Beatriz Eugenia Alvarado-Llano, María Camila Bolívar-Rocha, Marcela Arrivillaga-Quintero, Pilar Camargo-Plazas, Julián Andrés Torres-Isasiga, Sheila Andrea Gómez-Peñalosa, Ernesto Martínez-Buitrago, Jorge Luis Martínez-Cajas   +9 more
doaj   +1 more source

Re-evaluating the Potential Impact of Preexposure Prophylaxis (PrEP) in Achieving HIV Elimination in the United States: Insights From Modeling. [PDF]

Open Forum Infect Dis
Baron J, Tchelidze T, Parkin N, Robinson N, La Brot B, Hazra A, Mayer KH.   +6 more
europepmc   +1 more source

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source