Results 41 to 50 of about 617,401 (307)

Considerații în legătură cu unele termene din cadrul procedurii prealabile sesizării instanței de contencios administrativ

Revista Transilvană de Ştiinţe Administrative, 1999
Legea nr. 29/19901 reglementează o procedură prealabilă sesizării instanţei, care este formată din două etape distincte: prima dintre ele, recursul graţios la autoritatea administrativ emitentă a actului atacat este obligatorie, fiind o condiţie necesară
Dacian DRAGOŞ
doaj  

Improving the Patient Colonoscopy Prep Experience [PDF]

, 2017
AIM: To improve patient prep compliance, prep quality, and an overall better experience by designing a prep specific website that will address the most common prep questions and concerns Once launched, the website address will be placed on printed ...
Cohen, MD, Robert, Cosgrove, MD, Natalie, Dargan, MD, Andrew, Dhanekula, MD, Raja K., Francis, MD, Gloria, Gandhi, MD, Komal, Kistler, MD, Andrew, Malamood, MD, Mark, Moleski, MD, Stephanie M., Niu, MD, Bolin, Prieto, MD, Jorge, Reddy, MD, Sheela S., Shah, MD, Apeksha, Tofani, MD, Christina, Zabolotsky, MD, Andrew   +14 more
core   +1 more source

The utility of efavirenz-based prophylaxis against HIV infection. A systems pharmacological analysis [PDF]

, 2019
Pre-exposure prophylaxis (PrEP) is considered one of the five “pillars” by UNAIDS to reduce HIV transmission. Moreover, it is a tool for female self-protection against HIV, making it highly relevant to sub-Saharan regions, where women have the highest ...
Dickinson, Laura, Duwal, Sulav, Khoo, Saye, Kleist, Max von, Seeler, Daniel   +4 more
core   +4 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Despre rezistența la schimbare

Revista Transilvană de Ştiinţe Administrative, 1999
“Bolnavii care suferă de sindromul Down nu pot învăţa să scrie sau să citească niciodată.” Toată lumea crede (mai bine spus, credea) că această afirmaţie este un adevăr indiscutabil. Până când unul dintre persoanele suferind de acest sindrom, neştiind că
Ciprian TRIPON, Călin GHIOLȚAN
doaj  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Current Perspectives on the Impact of Pre-Exposure Prophylaxis Stigma Regarding Men Who Have Sex with Men in the United States

HIV/AIDS: Research and Palliative Care, 2020
Patrick D Herron Department of Family and Social Medicine, Albert Einstein College of Medicine, Bronx, NY, USACorrespondence: Patrick D Herron Email patrick.herron@einsteinmed.orgAbstract: Pre-exposure prophylaxis or PrEP is a Food and Drug ...
Herron PD
doaj  

Facilitators and Barriers to Prescribing PreExposure Prophylaxis (PrEP) for the Prevention of HIV [PDF]

, 2016
Background: What is PrEP and who gets it? PrEP is the use of medication by individuals to prevent HIV contraction, approved in 2012 after demonstrating safety and efficacy in the iPrEx study and Partners PrEP2 trials.
Flanagan, Theresa B., Graham, Margaret M., Huynh, Tihn T., Jacobsen, Peter, Larrabee, Jerry, Luzim, Derek L., Miller, Alexandra K., Nguyen, David M., Shen, Yueyue   +8 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source