Results 101 to 110 of about 9,221,826 (337)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Engineered microbial platform confers resistance against heavy metals via phosphomelanin biosynthesis

open access: yesNature Communications
Environmental concerns are increasingly fueling interest in engineered living materials derived from microbial sources. Melanin biosynthesis in microbes, particularly facilitated by recombinant tyrosinase expression, offers sustainable protection for the
Xiaokang Ren   +7 more
doaj   +1 more source

Indexing, screening, coding and cataloging of earth resources aircraft mission data [PDF]

open access: yes
Tasks completed are as follows: (1) preparation of large Area Crop Inventory experiment for data base entry;(2) preparation of Earth Observations Aircraft Flight summary reports for publication; (3) updating of the aircraft mission index coverage map and

core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Process for preparing sterile solid propellants Patent [PDF]

open access: yes, 1967
Using ethylene oxide in preparation of sterilized solid rocket propellants and encapsulating ...
Montgomery, L. C., Morelli, F. A.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The preparation of crystalline lactic acid [PDF]

open access: yes, 1933
On account of its importance in intermediary metabolism, lactic acid was among the first compounds chosen in our plan, which we have described in a previous communication (1), to augment the available data on the free energies of formation of substances ...
Borsook, Henry   +2 more
core  

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Momordicae Semen: A Review of Phytochemistry, Pharmacology, Toxicology, Herbal Processing, Clinical Applications, and Q-Markers Prediction

open access: yesDrug Design, Development and Therapy
Xin Deng,1 Yanmei Liu,1 Xiaoli Zhu,1 Hui Zhu,1 Cheng Huang,1 Yan Hong,1,2 Deling Wu,2 Yanquan Han1– 3 1Grade Three-Level Laboratory of TCM Preparation, State Administration of Traditional Chinese Medicine, The First Affiliated Hospital of Anhui ...
Deng X   +7 more
doaj  

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