Results 51 to 60 of about 35,813,844 (294)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Sample preparation process.

, 2021
Sample preparation process.
Lu Gao (44114), Binfeng Qin (11873756), Mingkun Pang (11873753), Tianjun Zhang (4840680)   +3 more
core   +1 more source

The Impact of Process Safety on Productivity and the Bottom Line [PDF]

, 1998
PresentationHow does process safety impact productivity and the bottom-line? A total safety process. Kvaerner utilizes aspects of Process Safety Management to control the safety quality of its process design. PSM also drives many aspects of construction,
Gaylon Fortune
core   +1 more source

Microneedle delivery systems for vaccines and immunotherapy

Smart Molecules
Microneedles (MNs) offer a precise and minimally invasive platform for delivering vaccines and therapeutic agents directly into the skin, leveraging the abundance of tissue‐resident immune cells to elicit robust and durable immune responses.
Haiyao Jia, Jinyuan Liu, Mengqian Shi, Manzar Abbas, Ruirui Xing, Xuehai Yan   +5 more
doaj   +1 more source

Study on Preparation Method of Terminal Blend Rubberized Asphalt Binder

Frontiers in Materials, 2020
Terminal Blend (TB) asphalt rubber is prepared by being sheared with high speed for a long time a high temperature and has good low temperature performance and anti-fatigue performance.
Juan Xie, Juan Xie, Yongning Zhang, Yueming Yang   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Preference of negatively charged membranes in magnesium and lithium separation by nanofiltration

Nature Communications
Despite the traditional co-ion competition theory suggesting that positively charged nanofiltration (NF) membranes are best for Li⁺/Mg²⁺ separation, practical applications predominantly utilize negatively charged membranes.
Lulu Liu, Shihong Lin, Xinyi Xu, Yinhua Wan, Weijie Song, Jianquan Luo   +5 more
doaj   +1 more source

Optimization of Ultra-High-Pressure Extraction and Comparative Evaluation of Antioxidant Activity and Flavonoid Composition in Guanxiang Leaves

Separations
This paper aimed to optimize the ultra-high-pressure extraction process of flavonoids from guanxiang leaves, evaluate their antioxidant capacity, and identify the flavonoids. Methods: Guanxiang leaves were used as the raw material. The extraction process
Jinyan Zhang, Jiyao Kang, Haoqian Yan, Yang Zhang, Zhenhu Guo, Lihui Liu, Guifeng Zhang, Yu Zhang   +7 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source