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Разработка и регистрация лекарственных средств, 2022 Introduction. An increasing number of studies conducted in various countries in the field of biopharmacy convincingly show the differences in the physiological effects on the human body of stereoisomers of pharmaceutical substances. As a rule, one of the
V. N. Tsarev +2 more
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Chiral Separations in Preparative Scale: A Medicinal Chemistry Point of View
Molecules, 2020 Enantiomeric separation is a key step in the development of a new chiral drug. Preparative liquid chromatography (LC) continues to be the technique of choice either during the drug discovery process, to achieve a few milligrams, or to a scale-up during ...
Madalena M.M. Pinto +2 more
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ISOLASI LISOZIM ALBUMIN TELUR AYAM RAS DENGAN METODE KROMATOGRAFI PENUKAR ION
Jurnal Teknologi dan Industri Pangan, 2018 Lysozyme is one of the proteins found in hen egg albumin. Besides known as antimicrobial agents, lysozyme hydrolysis products can also function as antioxidants and as angiotensin converting enzyme (ACE) inhibitors.
Zakiah Wulandari +4 more
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Fast preparative isoelectric focusing of phycocyanin subunits in layers of granulated gels [PDF]
, 1987 A new method is presented for the fast preparative separation of the light-harvesting photosynthetic pigment C-phycocanin into its and subunits, which is based on isoelectric focusing in layers of granutaled gels containing 7 M urea. The method has been
Fischer, Richard +5 more
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Separations, 2019 In the countercurrent chromatography and centrifugal partition chromatography, separation method transfer and scale-up is often described as an easy and straightforward procedure.
Simon Roehrer, Mirjana Minceva
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Optimization of mobile phase composition for preparative separation of profens enantiomers by chiral liquid chromatography [PDF]
, 2008 In this paper it will be presented and discussed the experimental and simulation results obtained for the preparative separation of ketoprofen and flurbiprofen enantiomers by chiral liquid chromatography.
Berger, Guido +8 more
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Optimization of Automatic Synthesis and Separation of [18F] AV-45 and Quality Control
Frontiers in Chemistry, 2022 Objective: Based on the Tracerlab FXF-N platform, a synthesis program and preparative high-performance liquid chromatography (HPLC) purification program edited by us can stably and repeatedly produce [18F] AV-45 without changing the process. The [18F] AV-
Qi-Zhou Zhang +5 more
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Plants, 2021 We previously reported that Lepechinia meyenii (Walp.) Epling has antioxidant and aldose reductase (AR) inhibitory activities. In this study, L. meyenii was extracted in a 50% MeOH and CH2Cl2/MeOH system.
Guanglei Zuo +7 more
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Efficient Biocatalytic Synthesis of Dihalogenated Purine Nucleoside Analogues Applying Thermodynamic Calculations [PDF]
, 2020 The enzymatic synthesis of nucleoside analogues has been shown to be a sustainable and efficient alternative to chemical synthesis routes. In this study, dihalogenated nucleoside analogues were produced by thermostable nucleoside phosphorylases in ...
Giessmann, Robert T. +9 more
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Influence of electrostatic interactions in electrophoretic membrane contactors [PDF]
, 2002 In electrophoretic separators, a porous membrane is used to put into contact two flowing liquids between which an electrically driven mass transfer takes place. As far as charged solutes are concerned, the mass transfer can be affected by electrostatic
Galier, Sylvain +1 more
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