Results 101 to 110 of about 498,894 (298)

Study of pharmaceutical industrial problems [PDF]

The growth of a human colon carcinoma cell line (SK-CO-1) and its production of carcinoembryonic antigen (CEA) in monolayer culture and on single layers of glass beads in unit gravity were evaluated.
Pincus, J. H.
core   +1 more source

Kuhn on discovery and the case of Penicillin [PDF]

, 2006
Book description: Nowadays, philosophy and methodology of science appear as a combination of novelty and continuity. This blend is clear both in the general approaches to science (those thought of as any science) and in the specific perspectives on ...
Gillies, D.
core  

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Preparation of contemporary dishes and a functional drink using Japan's heirloom vegetable, Katsura-uri

Journal of Ethnic Foods, 2018
Background: The fruit of Katsura-uri, traditionally used in the preparation of pickles in Japan, is facing an extinction crisis. In addition to the traditional dishes prepared from Katsura-uri, alternative dishes using the fruit should be devised to ...
Azusa Sasaki, Yasushi Nakamura, Yukiko Kobayashi, Wataru Aoi, Takako Nakamura, Koji Shirota, Noboru Suetome, Michiaki Fukui, Tomoaki Matsuo, Shigehisa Okamoto, Yuri Tashiro, Eun Y. Park, Kenji Sato   +12 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

The Cooking Characteristics of Diacylglycerol rich Cooking Oil When Preparing Dishes

Journal for the Integrated Study of Dietary Habits, 2001
生活習慣病, 肥満防止などが可能と考えられる体に脂肪が蓄積しにくいジアシルグリセロールを主成分とする油 (市販, 健康エコナクッキングオイル: 花王株式会社製, DAG-O) の調理性について, 同一原料から採油したトリアシルグリセロールを主成分とする油 (TAG-O) を対照に, 油の使用量が多い揚げ物 (素揚げ, から揚げ, パン粉揚げ, てんぷら), 妙め物, サラダ (ドレッシング) を調製し, 検討して以下の知見が得られた.1. 官能評価法による評価の結果, DAG-Oで揚げ物, 妙め物, サラダを調理したところ, 調理直後においてはTAG-Oで調理した場合とほぼ同じ評価を得, てんぷらにおいてはテクスチャー項目でTAG-Oに比べてむしろ高い評価を得た.2 ...
Hisae OGAWA, Sachiko OKUSHIMA, Hiromi KODAMA   +2 more
openaire   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Unlocking the Power of Quercetin‐Encapsulated Mesoporous Bioactive Glass Nanoparticles: A Multifunctional Approach to Bone Regeneration

Advanced Engineering Materials, EarlyView.
Mesoporous bioactive glass nanoparticles (MBGNs) are investigated for bone regeneration given their remarkable structural and functional properties. MBGNs are functionalized with Mn and Cu and incorporated with quercetin, a natural flavonoid exhibiting antioxidant, anti‐inflammatory, and antimicrobial properties.
Giovanni Lo Bello, Qaisar Nawaz, Pier Francesco Ferrari, Laura Pastorino, Roberto Raiteri, Aldo R. Boccaccini   +5 more
wiley   +1 more source

Effects of Oil Types on the Taste and Flavor Quality of Prepared Stir-fried Rice

Shipin gongye ke-ji
Oil was one of the essential components in prepared stir-fried rice. In this study, the effects of oil types on the taste and sensory quality of prepared stir-fried rice were evaluated, considering moisture content, texture, color, and lipid oxidation ...
Shuyi LI, Ya SU, Jieru ZHANG, Yanzhen LONG, Yiping CHEN, Min ZHANG   +5 more
doaj   +1 more source