Results 1 to 10 of about 221,234 (343)

ChAdOx1 nCoV-19 (AZD1222) vaccine candidate significantly reduces SARS-CoV-2 shedding in ferrets

npj Vaccines, 2021
Vaccines against SARS-CoV-2 are likely to be critical in the management of the ongoing pandemic. A number of candidates are in Phase III human clinical trials, including ChAdOx1 nCoV-19 (AZD1222), a replication-deficient chimpanzee adenovirus-vectored ...
Glenn A. Marsh, Alexander J. McAuley, Gough G. Au, Sarah Riddell, Daniel Layton, Nagendrakumar B. Singanallur, Rachel Layton, Jean Payne, Peter A. Durr, Hannah Bender, Jennifer A. Barr, John Bingham, Victoria Boyd, Sheree Brown, Matthew P. Bruce, Kathie Burkett, Teresa Eastwood, Sarah Edwards, Tamara Gough, Kim Halpin, Jenni Harper, Clare Holmes, William S. J. Horman, Petrus Jansen van Vuren, Suzanne Lowther, Kate Maynard, Kristen D. McAuley, Matthew J. Neave, Timothy Poole, Christina Rootes, Brenton Rowe, Elisha Soldani, Vittoria Stevens, Cameron R. Stewart, Willy W. Suen, Mary Tachedjian, Shawn Todd, Lee Trinidad, Duane Walter, Naomi Watson, Trevor W. Drew, Sarah C. Gilbert, Teresa Lambe, S. S. Vasan   +43 more
doaj   +1 more source

Strategic considerations on developing a CHIKV vaccine and ensuring equitable access for countries in need

npj Vaccines, 2023
Chikungunya is an arboviral disease caused by the chikungunya virus (CHIKV) afflicting tropical and sub-tropical countries worldwide. It has been identified as a priority pathogen by the Coalition for Epidemics Preparedness Innovations (CEPI) and as an ...
Neil Cherian, Alison Bettis, Arminder Deol, Arun Kumar, Jose Luis Di Fabio, Amol Chaudhari, Solomon Yimer, Raafat Fahim, Timothy Endy   +8 more
doaj   +1 more source

Framing the future of the COVID-19 response operations in 2022 in the WHO African region

Global Health Action, 2022
Background With the evolving epidemiological parameters of COVID-19 in Africa, the response actions and lessons learnt during the pandemic’s past two years, SARS-COV 2 will certainly continue to circulate in African countries in 2022 and beyond.
Thierno Balde, Boniface Oyugi, Humphrey Karamagi, Joseph Chukwudi Okeibunor, Ishata Nannie Conteh, Nonso Ephraim Ejiofor, Phionah Atuhebwe, Miriam Nanyunja, Amadou Bailo Diallo, Richard Mihigo, Zabulon Yoti, Fiona Braka, Abdou Salam Gueye   +12 more
doaj   +1 more source

Availability and use of Standards in vaccine development

npj Vaccines, 2023
Reference materials are critical in assay development for calibrating and assessing their suitability. The devasting nature of the COVID-19 pandemic and subsequent proliferation of vaccine platforms and technologies has meant that there is even a greater
Michael Selorm Avumegah, Giada Mattiuzzo, Anna Särnefält, Mark Page, Karen Makar, Janet Lathey, June Kim, Solomon Abebe Yimer, Danielle Craig, Ivana Knezevic, Valentina Bernasconi, Paul A. Kristiansen, Ingrid Kromann   +12 more
doaj   +1 more source

Characterisation and natural progression of SARS-CoV-2 infection in ferrets

Scientific Reports, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the infectious disease COVID-19, which has rapidly become an international pandemic with significant impact on healthcare systems and the global economy.
Gough G. Au, Glenn A. Marsh, Alexander J. McAuley, Suzanne Lowther, Lee Trinidad, Sarah Edwards, Shawn Todd, Jennifer Barr, Matthew P. Bruce, Timothy B. Poole, Sheree Brown, Rachel Layton, Sarah Riddell, Brenton Rowe, Elisha Soldani, Willy W. Suen, Jemma Bergfeld, John Bingham, Jean Payne, Peter A. Durr, Trevor W. Drew, Seshadri S. Vasan   +21 more
doaj   +1 more source

COVID-19 case management strategies: what are the options for Africa?

Infectious Diseases of Poverty, 2021
The ongoing coronavirus disease 2019 (COVID-19) pandemic has put a strain on health systems globally. Although Africa is the least affected region to date, it has the weakest health systems and an exponential rise in cases as has been observed in other ...
Joy Luba Lomole Waya, David Ameh, Joseph Lou K. Mogga, Joseph F. Wamala, Olushayo Oluseun Olu   +4 more
doaj   +1 more source

What did we learn from preparing for cross-border transmission of Ebola virus disease into a complex humanitarian setting – The Republic of South Sudan?

Infectious Diseases of Poverty, 2020
Background Following the West Africa Ebola virus disease (EVD) outbreak (2013–2016), WHO developed a preparedness checklist for its member states. This checklist is currently being applied for the first time on a large and systematic scale to prepare for
Olushayo Oluseun Olu, Richard Lako, Joseph Francis Wamala, Patrick Otim Ramadan, Caroline Ryan, Ifeanyi Udenweze, Kibebu Berta, Argata Guracha Guyo, Alex Sokemawu, Michael Tukuru, Henry John Gray, Alex Chimbaru   +11 more
doaj   +1 more source

In Vitro and In Vivo Characterization of a Pigeon Paramyxovirus Type 1 Isolated from Domestic Pigeons in Victoria, Australia 2011

Viruses, 2021
Significant mortalities of racing pigeons occurred in Australia in late 2011 associated with a pigeon paramyxovirus serotype 1 (PPMV-1) infection. The causative agent, designated APMV-1/pigeon/Australia/3/2011 (P/Aus/3/11), was isolated from diagnostic ...
Songhua Shan, Kerri Bruce, Vittoria Stevens, Frank Y. K. Wong, Jianning Wang, Dayna Johnson, Deborah Middleton, Kim O’Riley, Sam McCullough, David T. Williams, Jemma Bergfeld   +10 more
doaj   +1 more source

Coordination mechanisms for COVID-19 in the WHO Regional office for Africa

BMC Health Services Research, 2022
Aim This study describes the coordination mechanisms that have been used for management of the COVID 19 pandemic in the WHO AFRO region; relate the patterns of the disease (length of time between onset of coordination and first case; length of the wave ...
Nsenga Ngoy, Boniface Oyugi, Paul O. Ouma, Ishata Nannie Conteh, Solomon Fisseha Woldetsadik, Miriam Nanyunja, Joseph Chukwudi Okeibunor, Zabulon Yoti, Abdou Salam Gueye   +8 more
doaj   +1 more source

Moving from rhetoric to action: how Africa can use scientific evidence to halt the COVID-19 pandemic

Infectious Diseases of Poverty, 2020
The ongoing pandemic of the coronavirus disease 2019 has spread rapidly to all countries of the world. Africa is particularly predisposed to an escalation of the pandemic and its negative impact given its weak economy and health systems.
Olushayo Oluseun Olu, Joy Luba Lomole Waya, Sylvester Maleghemi, John Rumunu, David Ameh, Joseph Francis Wamala   +5 more
doaj   +1 more source