ABSTRACT Background Lifestyle interventions targeting metabolic health may influence chronic kidney disease (CKD) risk, particularly among adults with type 2 diabetes and obesity. We evaluated real‐world associations between a telehealth‐delivered, individualized nutrition therapy program (VINT) and CKD incidence and progression compared with usual ...
Shaminie J. Athinarayanan +7 more
wiley +1 more source
Comparison of preprints and their corresponding peer-reviewed publications in the health field: a scoping review. [PDF]
Zoghbi MS +6 more
europepmc +1 more source
Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini +4 more
wiley +1 more source
Cross-Disorder Pruning-Plasticity-Aging Architecture in Substance Use Disorders and Anxiety: Transcriptome-Wide Association Insights and Mechanistic Synthesis. [PDF]
Cheung N.
europepmc +1 more source
Combating ageing beyond the cell: Emerging roles of extracellular proteostasis
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh +7 more
wiley +1 more source
The Story behind the Science: Preprints of pandemic potential-how bioRxiv and medRxiv brought preprints to the life sciences. [PDF]
Sever R.
europepmc +1 more source
A guide to laser microdissection‐based proteomics
This review takes researchers through the full laser microdissection proteomics workflow—from tissue preparation and image analysis to sample processing and mass spectrometry—offering practical solutions to common challenges at each step. Real‐world examples from across the field illustrate how the technology is being applied to disease tissue, making ...
Cheng Shen +3 more
wiley +1 more source
Abstract Introduction Hypertension is a major cardiovascular risk factor and has increased among people living with HIV. However, evidence on its association with HIV status remains inconsistent. This systematic review aimed to assess the association between HIV status and hypertension and to examine, through subgroup analyses, whether this association
Mariene Garcia Gomes +5 more
wiley +1 more source
To Be or Not to Be a Worker: Legal Uncertainty and Precarious Employment in the European Union
Abstract Precarious employment has gradually moved onto the European Union (EU) policy agenda, so far culminating in the proclamation of the European Pillar of Social Rights (the Pillar). However, the effectiveness of these renewed social ambitions is challenged by legal uncertainty and entangled in ongoing political and legal disputes over the ...
Dorte Sindbjerg Martinsen +2 more
wiley +1 more source
Use of ambient AI scribe in physicians' clinical documentation: a protocol for a systematic review on effectiveness, efficiency, and satisfaction. [PDF]
Garcia Sanchez C +6 more
europepmc +1 more source

