Results 161 to 170 of about 12,508 (203)
Reduced prepulse inhibition in unaffected siblings of schizophrenia patients
Psychophysiology, 2005 We investigated whether prepulse inhibition of the startle response is reduced in siblings of schizophrenia patients compared to age- and sex-matched healthy controls.
Veena Kumari +2 more
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Biological Psychiatry, 2006
Atypical antipsychotics have been assessed for normalization effects on deficient sensory gating as indexed by prepulse inhibition (PPI) in schizophrenics with generally positive, although somewhat conflicting, results.We tested the acute effect of clozapine on startle, PPI, and attention, working memory, and executive functioning in 28 healthy male ...
Franz X Vollenweider, Philipp A Csomor
exaly +3 more sources
Atypical antipsychotics have been assessed for normalization effects on deficient sensory gating as indexed by prepulse inhibition (PPI) in schizophrenics with generally positive, although somewhat conflicting, results.We tested the acute effect of clozapine on startle, PPI, and attention, working memory, and executive functioning in 28 healthy male ...
Franz X Vollenweider, Philipp A Csomor
exaly +3 more sources
Prepulse-elicited startle in prepulse inhibition
Biological Psychiatry, 2004Prepulse inhibition (PPI) has become a major experimental paradigm in the study of psychiatric disorders. In this study, a potential confound in measurement and interpretation of PPI, namely startle reactions to so-called "nonstartling" prepulses, was examined.Prepulses of 80, 85, and 90 dB(A) were presented on their own or followed by a pulse of 115 ...
Dahmen, Johannes C., Corr, Philip J.
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On the mechanism of prepulse inhibition☆
Physiology & Behavior, 1974Abstract Prepulse inhibition of the acoustic startle response in rats was studied in normal or sham-operated animals or animals with bilateral lesions in the frontal poles, dorsal hippocampus and overlying parietal cortex, parietal cortex alone, or bilateral electrolytic lesions in the motor nuclei of the fifth and seventh cranial nerves which ...
P M, Groves +3 more
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The effects of multiphasic prepulses on automatic and attention-modulated prepulse inhibition
Cognitive Processing, 2017Prepulse inhibition (PPI) is widely viewed as an operational measure of sensorimotor gating. Previous research has shown that sensorimotor gating can occur automatically and also can be influenced by selective attention. The present research investigated the relationship of the transient detection response (TDR) with automatic and attention-modulated ...
Albert B. Poje, Diane L. Filion
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Biological Psychiatry, 2006
Both prepulse inhibition (PPI) and prepulse facilitation (PPF) deficits have been reported in schizophrenia patients, but the use of different experimental parameters across laboratories makes direct comparisons of results difficult. We assessed the effects of different parameters on PPI and PPF in normal subjects.Eyeblink startle was measured in 14 ...
Ming H Hsieh, Neal R Swerdlow
exaly +3 more sources
Both prepulse inhibition (PPI) and prepulse facilitation (PPF) deficits have been reported in schizophrenia patients, but the use of different experimental parameters across laboratories makes direct comparisons of results difficult. We assessed the effects of different parameters on PPI and PPF in normal subjects.Eyeblink startle was measured in 14 ...
Ming H Hsieh, Neal R Swerdlow
exaly +3 more sources
Biological Psychiatry, 2004
Deficits in schizophrenia patients and their first-degree relatives have been reported in prepulse inhibition (PPI), a phenomenon that measures an early stage of information processing (sensorimotor gating). It is less clear whether these information processing deficits extend to prepulse facilitation (PPF), which measures a later stage of generalized ...
Jonathan K, Wynn +5 more
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Deficits in schizophrenia patients and their first-degree relatives have been reported in prepulse inhibition (PPI), a phenomenon that measures an early stage of information processing (sensorimotor gating). It is less clear whether these information processing deficits extend to prepulse facilitation (PPF), which measures a later stage of generalized ...
Jonathan K, Wynn +5 more
openaire +2 more sources
Reflexes Inhibited by a Prepulse
Perceptual and Motor Skills, 2016Prepulse inhibition refers to the inhibition of the startle reflexes by a weak stimulus (prepulse) that precedes a strong startle stimulus (pulse). Previous findings suggest that prepulse intensity affects prepulse inhibition amplitude and that prepulse inhibition amplitudes vary across onset intervals between the prepulse and pulse.
Ryoji, Nishiyama, Hiroyuki, Iso
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