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Discrepancies between prescribed daily doses and WHO defined daily doses of antibacterials at a university hospital [PDF]
British Journal of Clinical Pharmacology, 2006 Aims The defined daily doses (DDD) defined by the WHO are widely used as an indicator to measure antibiotic use in the hospital setting. However, discrepancies exist between countries in terms of antibiotic dosage. The aim of the present study was to compare, for each antibacterial agent available at our university hospital, the prescribed daily doses (
Xavier Bertrand +2 more
exaly +5 more sources
Association between opioid-related deaths and prescribed opioid dose and psychotropic medicines in England: a case-crossover study [PDF]
British Journal of Anaesthesia, 2021 BackgroundOpioid-overdose deaths are associated with poisoning with prescription and illicit opioids in the USA. In contrast, opioid-related deaths (ORDs) in the UK often involve drugs and substances of misuse, and may not be associated with a high dose ...
Li-Chia Chen +2 more
exaly +2 more sources
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Hospital statistics for antibiotics: defined versus prescribed daily dose
Infection, 2014Defined daily doses (DDD) are widely used as a unit to measure drug use in hospital and community settings. However, discrepancies exist between DDD and actual prescribed daily dose (PDD). The present study aims at estimating an alternative PDD (PDD-proxy) to calculate rates of systemic antibiotic consumption and to compare these results with those ...
Enrico Ricchizzi, Carlo Gagliotti
exaly +3 more sources
Saudi Pharmaceutical Journal, 2023 This study aimed to investigate the prescribing pattern of antipsychotic medications for schizophrenia using the British National Formulary total daily dose (TDD) online tool. We analysed data from the electronic medical records at King Khalid University Hospital (KKUH) of 272 patients diagnosed with schizophrenia who were prescribed both typical and ...
Haya Almalag, Jawza F Alsabhan
exaly +4 more sources
Epilepsia Open, 2023 AbstractObjectivesTo investigate the antiseizure medication (ASM) doses required to achieve seizure freedom and their correlation with the World Health Organization's defined daily doses (DDDs) in patients aged 16 years or older with newly diagnosed epilepsy.MethodsThe study included 459 patients with a validated diagnosis of new‐onset epilepsy ...
Jani Raitanen +2 more
exaly +6 more sources
International Journal of Clinical Pharmacy, 2017
Background Although defined daily doses (DDD) for antiepileptic drugs (AED) have been assigned only in combination therapy, based on the literature, most patients take them in monotherapy. Furthermore, discrepancies between DDD and prescribed daily dose (PDD) were observed.
Klára Fekete +2 more
exaly +3 more sources
Background Although defined daily doses (DDD) for antiepileptic drugs (AED) have been assigned only in combination therapy, based on the literature, most patients take them in monotherapy. Furthermore, discrepancies between DDD and prescribed daily dose (PDD) were observed.
Klára Fekete +2 more
exaly +3 more sources
Int. Journal of Clinical Pharmacology and Therapeutics, 2006
Prescribed daily doses (PDDs) of antiepileptics (N03A ATC group) were recorded for drugs used in monotherapy or in combination therapy in the University Hospital in Ostrava, Czechia. Plasma levels were used as an indicator of the quality of treatment.Request and reply forms for therapeutic drug monitoring (TDM) were used as a source of PDDs and plasma ...
B. Koristkova +4 more
openaire +2 more sources
Prescribed daily doses (PDDs) of antiepileptics (N03A ATC group) were recorded for drugs used in monotherapy or in combination therapy in the University Hospital in Ostrava, Czechia. Plasma levels were used as an indicator of the quality of treatment.Request and reply forms for therapeutic drug monitoring (TDM) were used as a source of PDDs and plasma ...
B. Koristkova +4 more
openaire +2 more sources
European Journal of Hospital Pharmacy, 2012
Background Different measurements to assess antibacterial use in hospitals have been described, many of them based on the WHO Defined Daily Dose (DDD) assignments. Although WHO accepts the update of DDDs, ‘changes of DDDs should be kept to a minimum and avoided as far as possible’.
J.F. Rodrigues +5 more
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Background Different measurements to assess antibacterial use in hospitals have been described, many of them based on the WHO Defined Daily Dose (DDD) assignments. Although WHO accepts the update of DDDs, ‘changes of DDDs should be kept to a minimum and avoided as far as possible’.
J.F. Rodrigues +5 more
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Prescribed daily doses and ‘risk factors’ associated with the use of benzodiazepines in primary care
Pharmacoepidemiology and Drug Safety, 1999To assess the extent, characteristics and determinants of benzodiazepine prescription in outpatient Primary Health Care.A clinical audit of a stratified random sample of Primary Health Care Centres in the seven islands and 1.6 million inhabitants region of 'Canarias' in Spain was carried out. From those centres, a random sample of 1045 clinical records
C, de las Cuevas +4 more
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Verschillen tussen WHO ‘Defined Daily Doses’ en ‘Prescribed Daily Doses’ van antibiotica
Medisch-Farmaceutische Mededelingen, 2006Op Europees niveau wordt veel onderzoek gedaan naar antibioticagebruik, zowel extra- als intramuraal 1,2. Voor het uitdrukken van blootstelling aan antibiotica wordt in het algemeen de ATC/DDD-methodologie van de WHO gebruikt. Hierbij wordt het aantal ‘defined daily doses’ (DDD’s) gedefinieerd als ‘de aangenomen gemiddelde onderhoudsdosering per dag ...
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