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Comparison of Defined versus Recommended versus Prescribed Daily Doses for Measuring Hospital Antibiotic Consumption

Infection, 2009
Hospital antibiotic use is usually measured by calculating the volume as the number of daily doses defined by the World Health Organization/Anatomical Therapeutic Chemical (WHO/ATC) index (DDDs) divided by a denominator indicating clinical activity, such as the number of occupied bed days.
W V Kern
exaly   +4 more sources

Effects of Once-Daily and Twice-Daily Dosing on Adherence With Prescribed Glipizide Oral Therapy for Type 2 Diabetes

Southern Medical Journal, 2002
We evaluated differences in adherence and persistence with prescribed therapy of once-daily (OD) dosing compared with twice-daily (BID) dosing of glipizide in patients with type 2 diabetes.The study cohort was derived from a pharmacy benefit manager claims database.
Christopher M, Dezii   +2 more
openaire   +2 more sources

High-dose antipsychotic therapy and reflective prescribing: development of an online tool for rapid, easy calculation of antipsychotic total daily dose

Australasian Psychiatry, 2020
Objective: Safe and effective antipsychotic prescribing is a fundamental skill in psychiatric practice; however, antipsychotic medications are not without risk. These risks are increased when antipsychotics are prescribed in high doses, with or without polypharmacy.
Korinne Northwood   +3 more
openaire   +5 more sources

Trends in Antibiotic Use at a University Hospital: Defined or Prescribed Daily Doses? Patient Days or Admissions as Denominator?

Infection, 2006
Hospital antibiotic use can be measured by calculating daily doses as defined by the WHO/ATC index (DDD) divided by the number of patient or occupied bed days. We wondered whether changes in antibiotic use density over time at a university hospital using this data format are similar in order of magnitude when compared with a different, alternative dose
W V Kern, P Kern
exaly   +4 more sources

[Is it preferable to prescribe 1 or 2 daily doses of sodium valproate?].

La Nouvelle presse medicale, 1983
Enteric-coated tablets containing 1 500 mg of sodium valproate (VPA) were administered in a randomized fashion either once or three times a day for 7 days to 6 healthy adult volunteers. Plasma total VPA levels and unbound fractions of the drug were determined 2-hourly on the last day of each treatment.
P, Loiseau   +4 more
openaire   +1 more source

Definition of patients treated with evidence based drugs in absence of prescribed daily doses: the example of acute myocardial infarction

Pharmacoepidemiology and Drug Safety, 2010
AbstractPurposeDefine patients treated with evidence‐based drugs in a cohort discharged after acute myocardial infarction (AMI) in absence of prescribed daily doses (PDD). To compare different drug use measures and analyze their impact on the effect estimate of risk factors related to drug use.MethodsAMI patients discharged in Rome during 2006–2007 ...
Valeria, Belleudi   +8 more
openaire   +2 more sources

Effect of computer-generated prompts on physician prescribing of multiple daily doses.

The Canadian journal of hospital pharmacy, 1987
Cost containment of health care costs and computerization of pharmacy services are two trends that have become evident in recent years. The work described here was an attempt to reduce the prescribing of multiple daily doses of medications that could be prescribed once or twice daily by utilizing a pharmacy computer system. Ten drugs were identified as
V, Atkinson, J D, Andrews
openaire   +1 more source

A drug utilisation study investigating prescribed daily doses of hypolipidaemic agents

2017
Objectives: To estimate average prescribed daily doses (PODs) for selected hypolipidaemic agents available on the South African market. Comparison of the estimated PODs with established ODDs (defined daily doses) and international dosage ranges. To investigate the age and gender of the users of the different hypolipidaemic drugs and drug groups. Design:
Truter, I, van W. Kotze, TJ
openaire   +1 more source

[Comparison of prescribed and defined daily doses (DDD) of selected antihypertensives--problems and conclusions].

Die Pharmazie, 1988
The comparison of prescribed and defined daily doses of 21 antihypertensive drugs showed minor to major differences, which have an impact on how to assess future drug demand and how to evaluate the therapeutic equivalence of various drugs. Relating problems concerning prescribing habits of drugs and research in drug demand are being discussed.
M, Schaefer, H, Audien
openaire   +1 more source

Discrepancies between Prescribed and Defined Daily Doses of Four-Pillar Therapy in Congestive Heart Failure Patients

Current Drug Therapy
introduction: The Defined Daily Dose (DDD) is a statistical metric for quantifying drug utilization that does not always align with the Prescribed Daily Dose (PDD). This study aimed to identify the discrepancies between prescribed daily dose (PDD) and defined daily dose (DDD) among congestive heart failure (CHF)
Nikita Pal   +3 more
openaire   +1 more source

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