Results 61 to 70 of about 172,066 (333)

Predictors of loss due to pharmaceutical fraud: evidence from the U.S.

open access: yesCost Effectiveness and Resource Allocation, 2022
Background Globally and in the U.S. in particular, pharmaceutical fraud account for a large number out of all crimes in health care, which result into severe costs to the society.
Yuriy Timofeyev   +2 more
doaj   +1 more source

A narrative review of global perspective on illicit drug utilization and substance use disorders

open access: yesArchives of Medicine and Health Sciences, 2022
Drug addiction and abuse are major public health issues across the globe that impact millions of people. Substance abuse and dependence seem to have been relatively high among university students and laborers and comparatively low among school students ...
Paila Bhanujirao   +3 more
doaj   +1 more source

Assessing the 2004-2018 fentanyl misusing issues reported to an international range of adverse reporting systems [PDF]

open access: yes, 2019
© 2019 Schifano, Chiappini, Corkery and Guirguis. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Chiappini, Stephania   +3 more
core   +4 more sources

Psychoactive prescription drug use and misuse in patients on opioid agonist treatment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro   +5 more
wiley   +1 more source

UNODC youth initiative: discussion guide. Draft. [PDF]

open access: yes, 2011
Contents: Section 1: Perceptions about Drug Use Section 2: What is Vulnerability? Section 3: The Direct Effects of Using Drugs Section 4: Abuse of Prescription Drug Section 5: Consequences and Risks Associated with Drug Use Section 6: Prevention ...

core  

Hypnotic doses of fazamorexant induced less impairment on balance and cognition than zolpidem in healthy younger and elderly individualse

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia   +3 more
wiley   +1 more source

Identifying Early Warning Signs: Addressing Youth Substance Use [PDF]

open access: yes, 2015
Of high school students 35 percent indicate they are current drinkers, 20 percent are binge drinkers, and 24 percent use marijuana. By the time they are seniors more than 20 percent will have used a prescription drug for a nonmedical purpose.

core  

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko   +9 more
wiley   +1 more source

Trends and variation in the use of andexanet alfa for the reversal of direct oral anticoagulants in NHS trusts in England

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Andexanet alfa was recommended by the National Institute for Health and Clinical Excellence (NICE) as an option in the management of life‐threatening gastrointestinal bleeding in patients taking apixaban or rivaroxaban in May 2021. A recent UK‐wide survey of local hospital protocols for the use of andexanet alfa suggested that practice ...
Louis Fisher   +11 more
wiley   +1 more source

Impact of Prior Therapeutic Opioid Use by Emergency Department Providers on Opioid Prescribing Decisions

open access: yesWestern Journal of Emergency Medicine, 2016
INTRODUCTION: Our study sought to examine the opioid analgesic (OA) prescribing decisions of emergency department (ED) providers who have themselves used OA therapeutically and those who have not.
Adam C Pomerleau   +5 more
doaj   +1 more source

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