Results 31 to 40 of about 3,145,963 (201)

Histone methyltransferase SETD2: An epigenetic driver in clear cell renal cell carcinoma

Frontiers in Oncology, 2023
SET domain-containing 2 (SETD2) is a lysine methyltransferase that catalyzes histone H3 lysine36 trimethylation (H3K36me3) and has been revealed to play important roles in the regulation of transcriptional elongation, RNA splicing, and DNA damage repair.
Mengxue Yu, Kaiyu Qian, Gang Wang, Gang Wang, Yu Xiao, Yu Xiao, Yuan Zhu, Lingao Ju, Lingao Ju   +8 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

ZmAGA1 enhances seed germination through raffinose hydrolysis and ZmSnRK1α-mediated starch mobilization in maize

Genome Biology
Background Raffinose family oligosaccharides are key endogenous factors influencing seed germination, with raffinose as the sole member in maize. However, the mechanisms by which raffinose regulates germination remain largely unexplored.
Wenyan Li, Wenjie Huang, Min Jin, Mingyang Ye, Zekai Zheng, Zhaofu Chen, Zhongjian Chen, Wenyang Zhang, Yuanyuan Chen, Jianbing Yan, Alisdair R. Fernie, Shijuan Yan   +11 more
doaj   +1 more source

Protein QID74 protects the cell wall of Trichoderma from degradation caused by its own chitinase, which lacks a carbohydrate-binding module

mBio
The fungal cell wall, formed by a chitin backbone, is critical for cellular integrity and environmental fitness. Mycoparasitic fungi of the genus Trichoderma deploy an arsenal of potent chitinases to dismantle the cell walls of prey fungi.
Jun-Jin Deng, Zhao-Fu Chen, Ming-Shu Zhang, Jing Liu, Zhi-Lin Wang, Jia-Zhou Li, Shaowen Wu, Xiao-Chun Luo   +7 more
doaj   +1 more source

Metabolomics analysis revealed biochemical changes in hepatopancreas and ovary of Litopenaeus vannamei during ovarian maturation

Aquaculture Reports, 2022
Pacific white shrimp (Litopenaeus vannamei) is one of the most prevalent crustacean species, understanding the metabolomics during gonad maturation in female L. vannamei is important to understand the regulatory mechanism of reproductive process.
De-Wei Ji, Fang Li, Li-Hua Hu, Kui Luo, Jiong-Ming Zhang, Mao-Cang Yan, Min Zhang   +6 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom, Dorella Scarponi, Giulia Zucchetti, Teresa Perillo, Maria Montanaro, Elisa Marconi, Chiara Rutigliano, Paolo Colavero, Paola Quarello, Marina Bertolotti, Monica Cellini, Carlo Clerici, Maurizio Mascarin, Francesca Bomben, Andrea Ferrari, the expert workgroup   +15 more
wiley   +1 more source

Research Progress on the Regulation of Important Agronomic Traits in Crops by Non-coding Genetic Resources

Guangdong nongye kexue
In traditional crop genetics research, protein-coding genes have always been the primary focus. However, recent scientific advances have revealed the critical role of non-coding genetic resources in regulating key agronomic traits such as crop yield ...
Yang YU, Qingfeng ZHU, Jiao XUE, Pei CHEN, Yanzhao FENG   +4 more
doaj   +1 more source

Gene Mining and Flavour Metabolism Analyses of Wickerhamomyces anomalus Y-1 Isolated From a Chinese Liquor Fermentation Starter

Frontiers in Microbiology, 2022
Luzhou-flavoured liquor is one of Chinese most popular distilled liquors. Hundreds of flavoured components have been detected from this liquor, with esters as its primary flavouring substance.
Xin Shi, Xin Wang, Xin Wang, Xiaoge Hou, Xiaoge Hou, Qing Tian, Ming Hui, Ming Hui   +7 more
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source