Results 51 to 60 of about 638,879 (312)

DNA Methylation-Based Panel Predicts Survival of Patients With Clear Cell Renal Cell Carcinoma and Its Correlations With Genomic Metrics and Tumor Immune Cell Infiltration

open access: yesFrontiers in Cell and Developmental Biology, 2020
DNA methylation based prognostic factor for patients with clear cell renal cell carcinoma (ccRCC) remains unclear. In the present study, we identified survival-related DNA methylation sites based on the differentially methylated DNA CpG sites between ...
Xiao-Ping Liu   +8 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Progress in Protein Interactomics Technologies and Their Applications to Plants Research

open access: yesGuangdong nongye kexue, 2022
Protein interactomics is a cutting-edge technology to identify and quantify the interaction of proteins with other metabolites or molecules like proteins, which has been an important part of plant systems biology and multi-omics research. In recent years,
Wenyang ZHANG   +3 more
doaj   +1 more source

Actively decaying or just poorly preserved? Can we tell when plant and invertebrate remains in urban archaeological deposits decayed? [PDF]

open access: yes, 2004
We have recendy argued that poorly preserved delicate macrofossil remains of plants and invertebrates in near-surface deposits in York are in active decay, rather than being preserved in stasis, part-way down the decay trajectory.
Hall, A., Kenward, H.
core  

Biodynamic Agriculture: The Journey from Koberwitz to the World, 1924-1938 [PDF]

open access: yes, 2011
In the last year of his life, the Austrian philosopher Rudolf Steiner challenged the direction and practice of contemporary agriculture. This was an early response to the proliferation of chemical agriculture.
Paull, John
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

What\u27s Working in Family-Based Services--or, What\u27s Left to Believe in During a Time of Such Doubt? [PDF]

open access: yes, 1997
This article is a qualitative, personal report from the field, designed to highlight current developments in family-based theory and practice that bring hopefulness to workers and clients.
Friedman, Roger
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The bioarchaeology of Anglo-Saxon Yorkshire: present and future perspectives [PDF]

open access: yes, 2000
The Anglo-Saxon period in Yorkshire - in terms of our knowledge of those questions which bioarchaeological studies are conventionally used to address - remains very much an unknown quantity, We can hardly claim even to know whether these questions are ...
Dobney, K., Hall, A., Kenward, H.
core  

Home - About - Disclaimer - Privacy