Results 71 to 80 of about 638,879 (312)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
These notes derive a number of technical results on nonlinear contraction theory, a comparatively recent tool for system stability analysis. In particular, they provide new results on the preservation of contraction through system combinations, a ...
Slotine, Jean-Jacques, Tabareau, Nicolas
core +3 more sources
Bioethics: Reincarnation of Natural Philosophy in Modern Science [PDF]
The theory of evolution of complex and comprising of human systems and algorithm for its constructing are the synthesis of evolutionary epistemology, philosophical anthropology and concrete scientific empirical basis in ...
Cheshko, Valentin Teodorovich +2 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
On Species Preservation and Non-Cooperative Exploiters [PDF]
Game-theoretic fisheries models typically consider cases where some players harvest a single common fish stock. It is, however, the case that these types of models do not capture many real world mixed fisheries, where species are bio-logical independent ...
Lone Grønbæk Kronbak, Marko Lindroos
core +1 more source
Setting people in their environment: plant and animal remains from Anglo-Scandinavian York [PDF]
INTRODUCTION: For the past millennium, the inhabitants of the centre of York have, whether hey knew it or not, been living on top of a compost heap in which are preserved all kinds of remains of Anglo-Scandinavian and early post-conquest life.
Hall, A., Kenward, H.
core
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Retention of Mercurial Preservatives in Desiccated Biological Products [PDF]
A variety of bacterins, vaccines, and antisera retained greater than 90% of their original level of mercurial preservative after lyophilization, and this might influence certain uses of these products.
openaire +2 more sources
Deliberate Extinction: Whether to Destroy the Last Smallpox Virus [PDF]
The target problem to be examined is smallpox. Specifically, what should we (the United States and the entire world) now do with the last known residual samples of the virus that causes this uniquely horrific disease?
Koplow, David A.
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

