Results 91 to 100 of about 3,145,963 (201)

Assembly and analysis of the complete mitochondrial genome of Leonurus japonicus (Lamiaceae)

Scientific Reports
Leonurus japonicus Houtt. (L. japonicus), as an important plant resource with both ornamental and medicinal value, has now spread worldwide and is widely studied.
Qun Hu, Qing Li, Yin Mao, Yongjian Luo, Zhijun Deng, Wenhu Zhang   +5 more
doaj   +1 more source

International Internet Preservation Consortium 2011 General Assembly, May 9-13, 2011

, 2011
Programme for the 2011 International Internet Preservation Consortium General ...
International Internet Preservation Consortium
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

IIPC Preservation Working Group Report to IIPC Steering Committee

, 2007
This report summarizes the formation of the Preservation Workgroup and its work conducted between June to December ...
International Internet Preservation Consortium. Preservation Working Group
core  

Preservation in Perspective

The ‘Preservation in Perspective’ conference, held in 2021 to mark the 10th anniversary of the Coordination Office for the Preservation of Written Cultural Heritage (KEK), provided an opportunity to discuss the present and future of original preservation.

core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Wheat Embryo Albumin and Its Peptide Alleviate Acute Exercise Fatigue as Energy Supplement

Foods
Wheat embryo albumin (WEA), rich in amino acids with a good balanced proportion, demonstrates plentiful biological activities. The effects of WEA and its peptide with the best antioxidant ability (F3) as a post-workout and pre-workout energy supplement ...
Aimei Liao, Xiaoxiao Li, Yanbing Wang, Zhirui Ding, Long Pan, Yinchen Hou, Quanping Liu, Jianzheng Li, Menghui Shang, Jihong Huang   +9 more
doaj   +1 more source

IIPC Preservation Working Group Table of Threats and Potential Solutions

, 2007
This text contains a table outlining threats to long-term preservation efforts, and potential standards, tools, or approaches to address these ...
International Internet Preservation Consortium. Preservation Working Group
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source