Results 81 to 90 of about 3,199,743 (304)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Accurate identification of high-quality seeds is crucial for maintaining superior crop traits. Lettuce is widely consumed vegetable with diverse varieties, however, the traditionally identification methods are both time-consuming and labor-intensive ...
Jinpeng Wei +7 more
doaj +1 more source
International Internet Preservation Consortium Quarterly highlight report: November - December 2010
This report summarizes the activities of the International Internet Preservation Consortium Preservation Working Group from the fourth quarter of ...
International Internet Preservation Consortium. Preservation Working Group
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Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The water content of cut flowers is a significant factor in their post-harvest quality. In this study, we examine the efficacy of silver nanoparticles (NS) on the longevity of cut gladiolus, with a focus on water state and distribution. We used Low-field
Xiumei Li +7 more
doaj +1 more source
Our study's goal was to screen novel biomarkers that could accurately predict the progression and prognosis of bladder cancer (BC). Firstly, we used the Gene Expression Omnibus (GEO) dataset GSE37815 to screen differentially expressed genes (DEGs ...
Yejinpeng Wang +15 more
doaj +1 more source
Archived Webinar: Media Preservation
Archived webinar.Content is available at the link in the URI fieldMade available in DSpace on 2013-05-08T20:58:48Z (GMT). No. of bitstreams: 1 license.txt: 4923 bytes, checksum: 3568ab34bde24044ec8ea05b1192aa03 (MD5) Previous issue date:Institute of ...
Illinois Collections Preservation Network
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The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
IIPC Preservation Working Group Report to IIPC Steering Committee
This report summarizes the formation of the Preservation Workgroup and its work conducted between June to December ...
International Internet Preservation Consortium. Preservation Working Group
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