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Technology of Data: Collection, Communication, Access and Preservation - IASSIST 2008

open access: yesIASSIST Quarterly, 2008
Technology of Data: Collection, Communication, Access and Preservation - IASSIST ...
Editors
doaj   +1 more source

Data-driven approach for modeling Reynolds stress tensor with invariance preservation [PDF]

open access: green, 2023
Xuepeng Fu   +4 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Privacy preservation in self-governing openness of data

open access: yes大数据, 2018
The openness of data is very important for improving the application value of data resource.However,due to the consideration of privacy preservation,data should be open under supervision.That is,data should be in the mode of selfgoverning openness.For ...
Zhihui WANG, Xuchen ZHOU, Yun ZHU
doaj  

Ensuring Topological Data-Structure Preservation under Autoencoder Compression due to Latent Space Regularization in Gauss--Legendre nodes [PDF]

open access: green, 2023
Chethan Krishnamurthy Ramanaik   +5 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Appraisal Guidance for the Preservation of Research Data

open access: green, 2022
Jonathan Dorey   +2 more
openalex   +1 more source

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