Results 121 to 130 of about 7,510,132 (348)

Convexity preserving properties for Hamilton-Jacobi equations in geodesic spaces [PDF]

arXiv, 2017
We study the convexity preserving property for a class of time-dependent Hamilton-Jacobi equations in a complete geodesic space. Assuming that the Hamiltonian is nondecreasing, we show that in a Busemann space the unique metric viscosity solution preserves the geodesic convexity of the initial value at any time.
arxiv  

Flexible preservation and access solutions

, 2016
Short talk at the Preservation and Archiving special Interest Group (PASIG) meeting hosted at the New York Museum of Modern Art, Oct 2016. This talk looks at how data lifecycle models and capability maturity models can provide a structure when looking at what an organisation needs in a preservation and access solution.
openaire   +2 more sources

Tips for optimizing organ preservation solutions

Acta Biochimica Polonica, 2018
Organ injury during ischemia is one of the clinical problems of today's transplantation. It occurs during warm ischemia time (WIT) when the blood flow is cut off and during cold ischemia when a graft is chilled in situ until the circulation is restored to the recipient organism.
Barbara Dolińska, Aneta Ostróżka-Cieślik, Florian Ryszka   +2 more
openaire   +4 more sources

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

ET-Kyoto Solution plus Dibutyryl Cyclic Adenosine Monophosphate is Superior to University of Wisconsin Solution in Rat Liver Preservation

Cell Transplantation, 2008
ET-Kyoto solution (ET-K) is an extracellular-type organ preservation solution containing the cytoprotective disaccharide, trehalose. A previous study reported the supplement of dibutyryl cyclic adenosine monophosphate (db-cAMP) in conventional ET-K to ...
Xiangdong Zhao, Takaaki Koshiba DR., Takayuki Nakamura, Tatsuaki Tsuruyama, Ying Li, Toru Bando, Hiromi Wada, Koichi Tanaka   +7 more
doaj   +1 more source

Effect of preservation solution and distension pressure on saphenous vein's endothelium. [PDF]

Interact Cardiovasc Thorac Surg, 2022
Pimentel MD, Lobo Filho JG, Lobo Filho HG, de Castro Miguel E, Pinheiro Paiva SK, Silva Matos JI, Mesquita Fernandes MA, Fechine Jamacaru FV.   +7 more
europepmc   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Is a Preservation Solution for Living Donor Liver Transplantation Needed? Adding a New Chapter in LDLT! [PDF]

Transplant Direct, 2022
Dogar AW, Ullah K, Shams-Ud-Din, Abbas SH, Hussain A, Ghaffar A, Bilal H, Siraj-Ud-Din, Shoaib A, Ahmed B, Raza H, Hamza A, Hafeez Bhatti AB, Gupta S, Black SM, Mumtaz K.   +15 more
europepmc   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Concentration and Chain Length of Polyethylene Glycol in Islet Isolation Solution: Evaluation in a Pancreatic Islet Transplantation Model

Cell Transplantation, 2012
To improve graft preservation and consequently reduce conservation injuries, the composition of preservation solution is of outmost importance. It was demonstrated that the colloid polyethylene glycol (PEG), used in SCOT solution, has protective effects ...
S. Giraud, D. Bon, Y. Neuzillet, R. Thuillier, M. Eugene, T. Hauet, B. Barrou   +6 more
doaj   +1 more source