Results 141 to 150 of about 7,510,132 (348)
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Candida Contamination in Kidney and Liver Organ Preservation Solution: Does It Matter? [PDF]
J Clin Med, 2021 Stern S +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Graft Preservation Solution DuraGraft® Alleviates Vascular Dysfunction Following In Vitro Ischemia/Reperfusion Injury in Rats. [PDF]
Pharmaceuticals (Basel), 2021 Korkmaz-Icöz S +9 more
europepmc +1 more source
FEBS Open Bio, Volume 15, Issue 4, Page 542-550, April 2025.Co‐crystallization crystallizes a protein with its ligand, resulting in protein–ligand complex crystals. In contrast, soaking introduces a ligand into preformed protein crystals, allowing it to bind. Both methods produce crystals for X‐ray diffraction, which generates diffraction patterns that are analyzed to determine the three‐dimensional structure ...
Barbora Kaščáková +4 more
wiley +1 more source
Second-order invariant-domain preserving approximation to the multi-species Euler equations [PDF]
arXivThis work is concerned with constructing a second-order, invariant-domain preserving approximation of the compressible multi-species Euler equations where each species is modeled by an ideal gas equation of state. We give the full solution to the Riemann problem and derive its maximum wave speed.
arxiv
Protein crystallization and structure determination at room temperature in the CrystalChip
FEBS Open Bio, Volume 15, Issue 4, Page 532-541, April 2025.This protocol describes the implementation of a simple and user‐friendly microfluidic device called CrystalChip that allows the production of crystals by the counter‐diffusion method and their in situ analysis by serial crystallography. As an illustration, it is applied to determine the 3D structure of three proteins from data collected at room ...
Petr Pachl +9 more
wiley +1 more source
Effect of cold preservation/reperfusion on glycogen content of liver. Concise review
Annals of Hepatology, 2005 Livers cold preserved during variable periods of ischemia suffer functional, morphological and hemodynamic alteration, which are exacerbated when they are reperfused. One important injury is glycogen depletion during cold ischemia/ reperfusion. How liver
Alejandra B. Quintana +2 more
doaj
${\cal N}=(4,4)$ supersymmetric AdS$_3$ solutions in $d=11$ [PDF]
arXivWe derive necessary and sufficient conditions for AdS$_3$ solutions of $d=11$ supergravity to preserve ${\cal N}=(1,1)$ supersymmetry in terms of G-structures. Such solutions necessarily support an SU(3)-structure on the internal 8-manifold M$_8$, in terms of which we phrase the conditions for supersymmetry preservation. We use this to derive the local
arxiv